Laboratory of Cellular and Molecular Neuroscience
The Bowie Lab uses a combination of techniques to study ionotropic glutamate receptors (iGluRs), GABA-A receptors and more recently, Na+ channels. All ion-channel families are widespread in the vertebrate brain and fulfill many important roles in healthy individuals as well as being implicated in disease states associated with postnatal development (e.g. Autism, Schizophrenia), cerebral insult (e.g. Stroke, Epilepsy) and aging disorders (e.g. Alzheimer's disease, Parkinsonism). We are looking at iGluRs, GABA-A receptors and Na+ channels at two inter-related levels. In molecular terms, we are examining the events that occur when each ion-channel family is activated with the aim of developing novel therapeutic compounds. At the cellular level, we are studying the role that iGluRs, GABA-A receptors and Na+ channels fulfill in shaping the behaviour of neuronal circuits and how these processes may be corrected in disease states.
More About Us...
August 2017 - Photo of some of the attendees at the 2017 GEPROM Summer Student Symposium, including Amanda Perozzo, that was held at McGill on August 18th. See photo.
August 2017 - Some members of the Bowie lab travelled to Yale University for the 5th Annual iGluRetreat. The Retreat this year was particularly special as many of the speakers were brought from across the World to reflect upon and celebrate the career of Dr. James Howe, a Yale researcher who has made many seminal contributions to the study of inotropic glutamate receptors. See photo.
August 2017 - Dr. Bowie recently visited Rio de Janeiro as an invited speaker at the 38th International Union of Physiological Sciences (IUPS) conference. See photo.
June 2017 - Check out this interview of Loïs Miraucourt with Charles Tisseyre, talking about night vision!