Laboratory of Cellular and Molecular Neuroscience

Research Interests

The Bowie Lab uses a combination of techniques to study ionotropic glutamate receptors (iGluRs), GABA-A receptors and more recently, Na+ channels. All ion-channel families are widespread in the vertebrate brain and fulfill many important roles in healthy individuals as well as being implicated in disease states associated with postnatal development (e.g. Autism, Schizophrenia), cerebral insult (e.g. Stroke, Epilepsy) and aging disorders (e.g. Alzheimer's disease, Parkinsonism). We are looking at iGluRs, GABA-A receptors and Na+ channels at two inter-related levels. In molecular terms, we are examining the events that occur when each ion-channel family is activated with the aim of developing novel therapeutic compounds. At the cellular level, we are studying the role that iGluRs, GABA-A receptors and Na+ channels fulfill in shaping the behaviour of neuronal circuits and how these processes may be corrected in disease states.

More About Us...

Lab news

May 2017 - Bowie lab members are involved in the organizing of the "Beautiful Minds" Pint of Science 2017 event, which will take place on May 15-17th, 2017 in Montreal. See poster!

April 2017 - Dr. Bowie recently visited Northwestern University in downtown Chicago where he caught up with some old friends and colleagues from the neuroscience community. See photo.

April 2017 - MNG has been cancelled for this Wednesday. See link on the left.

April 2017 - Congratulations to Erik and Ryan for receiving a GREAT Travel Award from the IPN!

April 2017 - Congratulations to Ryan for receiving a Graduate Research Mobility Award from the Faculty of Medicine!

April 2017 - Congrats to graduate student, Adamo Mancino, and incoming graduate student, Amanda Perozzo from the University of Ottawa, who were each awarded the prestigious NSERC Masters student award. Adamo is currently working on voltage-gated sodium channels and Amanda will be working on ionotropic glutamate receptors.

Join the lab

We currently have positions available for graduate students and/or post-doctoral fellows. Click the link above for more information!

Find out more about us by looking us up on the NeuroTree