Artificial cells, blood substitutes, nanomedicine, regenerative medicine, cell encapsulation, gene therapy, enzyme therapy, cell therapy, tissue engineering, adult stem cells, bioencapsulation, nanocapsules, nanotechnology, nanobiotechnology, microcapsules, drug delivery, liver support,

Professor T.M.S. Chang ,OC,MD,CM,PhD,FRCP[C],FRS[C], 

Director, Artificial Cells & Organs Research Centre,   

Departments of Physiology, Medicine & Biomedical Engineering, 

Faculty of Medicine,  McGill University, 

Montreal,P.Q.,Canada   (artcell.med@mcgill.ca)

WHAT? WHEN? WHY? HOW? (brief description)
Artificial Cells, blood substitutes, microencapsulation and related areas

READING AND VIDEO FOR GENERAL AUDIENCE
(1)The Red Blood Cell Man by Andre Picard (Artificial Cells & blood substitutes) (in English) 

(2) Inventor and 50 years of Artificial Cells (in Chinese) with permission from Ming Poa News  (NEW)

(3) Video interview on artificial cells and blood substitutes (needs high speed internet and a few minutes for downloading) 

(4) Inventing Artificial Cells (in Chinese) with permission from Sept Days News http://www.medicine.mcgill.ca/artcell/1SeptDays.pdf   (NEW)

SCIENTIFIC REVIEWS 
(1) Detailed review on "Artificial Cells" from 2005 Nature Review Drug Discovery  
(2) "Nanobiotechnology based blood substitutes" from 2006 Trends in Biotechnology

(3) "Nanobiotechnological modification of hemoglobin and enzymes"  from 2008 Biochimica et Biophysica Acta: proteins & Proteomics 1784:1435-144 (NEW)

(4) "Nanobiotechnology for hemoglobin based blood substitutes" Preprint from 2009 Critical Care Clinics  http://www.medicine.mcgill.ca/artcell/criticalcare.pdf    (NEW) 
 

BOOKS (MONOGRAPHS for online access) 
(1) ARTIFICIALCELLS:biotechnology,nanotechnology,regenerative medicine,blood substitutes, bioencapsulation and cell/stem cell therapy. a 2007 454 page monograph by Chang. Click for content and free access to Chapter 1 on 50th anniversary of artificial cells.  

To read the rest of book  click here and then select "preveiw this book" (NEW)

(2)"BLOOD SUBSTITUTES: principles,methods,products & clinical trials" Monograph by Chang (1997) pdf format (posted with copyright permission)

(3) "ARTIFICIAL CELLS" Monograph by Chang(1972) pdf format.(posted with Copyright permission)

PUBLIC ISSUES ON BLOOD SUBSTITUTES
(1) Krever commission's Report on Blood Suply in Canada implemented by Quebec  
(2) Is there a priority to include blood substitutes in national blood supply policies?
(3) Is there a role for first generation blood substitutes in hemorrhagic shock?  
(4) Is there a need for blood substitutes in the new millennium and what should we expect in the way of safety and efficacy?by Chang,Greenburg,Chen,Feola & Simoni,Tsuchida,Biro,Yang,Alayash,Bucci,Hsia. 

(5) Safety of red blood cell substitutes as compared to stored donor red blood cells (NEW)

(4) Memorials for editorial board members:DeBakey,Kolff & Winslow (NEW) http://www.artcell.mcgill.ca/memorial.pdf 

XI ISBS; XII ISBS;XIII ISBS; 1st Congress International Academia of Nanomedicine;    Bioencapsulation Workshop;  others.  (UPDATED) 

TEACHING MATERIAL(For McGill students only)
Artificial Cells

RELATED WEBSITES:    CLICK HERE

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