Published proceedings:

  1. L. Mackay, A. Sherman, S.S. Stojilkovic and A. Khadra. Deciphering the Kinetic and Gating Properties of Purinergic P2X7 Receptor Channels. Athens Journal of Natural & Formal Sciences, Proceedings of the 1st Annual International Conference on Physics & Chemistry, Athens, Greece, 43-55.

Refereed Journal Articles:

  1. J.K. Lyda, Z.L. Tan, A. Rajah, A. Momi, L. Mackay, C.M. Brown and A. Khadra. Rac Activation is Key to Cell Motility and Directionality: An Experimental and Modelling Investigation. Computational and Structural Biotechnology Journal, in press, 2019.

  2. S. Farjami, R.P.D. Alexander, D. Bowie and A. Khadra. Switching in Cerebellar Stellate Cell Excitability in Response to a Pair of Inhibitory/Excitatory Pre-synaptic Inputs: A Dynamical System Perspective. Neural Computation, in press, 2019.

  3. J. Mitry, R.P.D. Alexander, S. Farjami, D. Bowie and A. Khadra. Modeling Excitability in Cerebellar Stellate Cells: Temporal Changes in Threshold, Latency and Frequency of Firing. Communications in Nonlinear Science and Numerical Simulation, 82, 105014, 2020.

  4. L. Mackay and A. Khadra. Dynamics of Mechanosensitive Nascent Adhesion Formation. Biophysical Journal, 117, 1057-1073, 2019.

  5. R.P.D. Alexander, J. Mitry, V. Sareen, A. Khadra and D. Bowie. Cerebellar Stellate Cell Excitability Is Coordinated by Shifts in the Gating Behavior of Voltage-Gated Na+ and A-Type K+ Channels.. eNeuro, 6(3) ENEURO.0126-19.2019.

  6. J. Lehnert and A. Khadra. How Pulsatile Kisspeptin Stimulation and GnRH Autocrine Feedback Can Drive GnRH Secretion: A Modeling Investigation. Endocrinology, 160, 1289-1306, 2019.

  7. K. Tang, C.G. Boudreau, C.M. Brown and A. Khadra. Paxillin Phosphorylation at Serine 273 and its Effects on Rac, Rho and Adhesion Dynamics. PLoS Computational Biology, 14, e1006303, 2018.

  8. S. Singha, K. Shao, Y. Yang, X. Clemente-Casares, P. Solé, A. Clemente, J. Blanco, Q. Dai, F. Song, S.W. Liu, J. Yamanouchi, C.S. Umeshappa, R.H. Nanjundappa, P. Detampel, M. Amrein, C. Fandos, R. Tanguay, S. Newbigging, P. Serra, A. Khadra, W.C.W Chan and P. Santamaria. Peptide-MHC-Based Nanomedicines for Autoimmunity Function as T-Cell Receptor Microclustering Devices. Nature Nanotechnology, 12, 701-710, 2017.

  9. L. Mackay, H. Zemkova, S.S. Stojilkovic, A. Sherman, A. Khadra. Deciphering the Regulation of P2X4 Receptor Channel Gating by Ivermectin Using Markov Models. PLoS Computational Biology, 13, e1005643, 2017.

  10. T.M. Mitre, M. Pietropaolo and A. Khadra. The Dual Role of Autoimmune Regulator in Maintaining Normal Expression Level of Tissue-Restricted Autoantigen in the Thymus: A Modeling Investigation. Mathematical Biosciences, 287, 12-23, 2017.

  11. L. Mackay, N. Mikolajewicz, S.V. Komarova and A. Khadra. Systematic Characterization of Dynamic Parameters of Intracellular Calcium Signals. Frontier in Physiology, 7, 525, 2016. Link to the software associated with the manuscript.

  12. T.M. Mitre, M.C. Mackey and A. Khadra. Mathematical Model of Galactose Regulation and Metabolic Consumption in Yeast. Journal of Theoretical Biology, 407, 238-258, 2016.

  13. S. Moran, S.M. Moenter and A. Khadra. A Unified Model for Two Modes of Bursting in GnRH Neurons. Journal of Computational Neuroscience, 40, 297-315, 2016.

  14. M. Jaberi-Douraki, M. Pietropaolo and A. Khadra. Continuum Model of T-Cell Avidity: Understanding Autoreactive and Regulatory T-Cell Responses in Type 1 Diabetes. Journal of Theoretical Biology, 383, 93-105, 2015.

  15. A. Khadra and S. Schnell. Development, Growth and Maintenance of Beta-Cell Mass: Models are also Part of the Story. Molecular Aspects of Medicine, Special Issue: Recent Advances in Pancreatic Beta Cell Failure and Diabetes, 42, 42-60, 2015.

  16. M.P. Morran, A. Vonberg A. Khadra and M. Pietropaolo. Immunogenetics of Type 1 Diabetes Mellitus. Molecular Aspects of Medicine, Special Issue: Recent Advances in Pancreatic Beta Cell Failure and Diabetes, 42, 78-90, 2015.

  17. A. Michels, L. Zhang, A. Khadra, J.A. Kushner, M.J. Redondo and M. Pietropaolo. Prediction and Prevention of Type 1 Diabetes: Update on Success of Prediction and Struggles at Prevention. Pediatric Diabetes, 16, 465-484, 2015.

  18. M. Jaberi-Douraki, S. Schnell, M. Pietropaolo and A. Khadra. Unraveling the Contribution of Pancreatic Beta-Cell Suicide in Autoimmune Type 1 Diabetes. Journal of Theoretical Biology, 375, 77-87, 2015.

  19. H. Zemkova, A. Khadra, M.B. Rokic, V. Tvrdonova, A. Sherman and S.S. Stojilkovic. Allosteric Regulation of the P2X4 Receptor Channel Pore Dilation. Pflügers Archiv - European Journal of Physiology, 467, 713-726, 2015.

  20. M. Jaberi-Douraki, S.W. Liu, M. Pietropaolo and A. Khadra. Autoimmune Responses in T1DM: Quantitative Methods to Understand Onset, Progression and Prevention of Disease. Pediatric Diabetes, 15, 162-174, 2014.

  21. M. Jaberi-Douraki, M. Pietropaolo and A. Khadra. Predictive Models of Type 1 Diabetes Progression: Understanding T-Cell Cycles and their Implications on Autoantibody Release. PLoS ONE, 9, e93326, 2014.

  22. J. Sugarman, S. Tsai, P. Santamaria and A. Khadra. Quantifying the Importance of pMHC Valency, Total pMHC Dose and Frequency on Nanoparticle Therapeutic Efficacy. Immunology and Cell Biology, 91, 350-359, 2013.

  23. A. Khadra, M. Tomic, Z. Yan, H. Zemkova, A. Sherman and S.S. Stojilkovic. Dual Gating Mechanism and Function of P2X7 Receptor Channels. Biophysical Journal, 104, 2612-2621, 2013.

  24. A. Khadra, Z. Yan, C. Coddou, M. Tomic, A. Sherman and S.S. Stojilkovic. Gating Properties of the P2X2a and P2X2b Receptor Channels: Experiments and Mathematical Modeling. Journal of General Physiology, 139, 333-348, 2012.

  25. A. Khadra, M. Pietropaolo, G.T. Nepom and A. Sherman. Investigating the Role of T-Cell Avidity and Killing Efficacy in Relation to Type 1 Diabetes Prediction. PLoS ONE, 6, e14796, 2011.

  26. Z. Yan, A. Khadra, A. Sherman and S.S. Stojilkovic. Calcium-Dependent Block of P2X7 Receptor Channel Function is Allosteric. Journal of General Physiology, 138, 437-452, 2011.

  27. Z. Yan*, A. Khadra*, S. Li, M. Tomic, A. Sherman and S.S. Stojilkovic. Experimental Characterization and Mathematical Modeling of the P2X7 Receptor Channel Gating. Journal of Neuroscience, 30, 14213-14224, 2010. (*These authors contributed equally to this work.)

  28. A. Khadra, S. Tsai, P. Santamaria and L. Edelstein-Keshet. On How Monospecific Memory-Like Autoregulatory CD8+ T Cells Can Blunt Diabetogenic Autoimmunity: A Computational Approach. Journal of Immunology, 185, 5962-5972, 2010.

  29. A. Khadra, P. Santamaria and L. Edelstein-Keshet. The Pathogenicity of Self-Antigen Decreases at High Levels of Autoantigenicity: A Computational Approach. International Immunology, 22, 571-582, 2010.

  30. X. Zhang, A. Khadra, D. Yang and D. Li. Unified Impulsive Fuzzy-Model-Based Controllers for Chaotic Systems with Parameter Uncertainties via LMI. Communications in Nonlinear Science and Numerical Simulations, 15, 105-114, 2010.

  31. A. Khadra, P. Santamaria and L. Edelstein-Keshet. The Role of Low Avidity T Cells in the Protection Against Type 1 Diabetes: A Modeling Investigation. Journal of Theoretical Biology, 256, 126-141, 2009.

  32. A. Khadra. Synchrony Due to Parametric Averaging in Neurons Coupled by a Shared Signal. Physica D, 238, 771-781, 2009.

  33. A. Khadra, X.Z. Liu and X. Shen. Robustness Analysis of Impulsive Synchronization of Chaotic Systems with Delayed Impulses. IEEE Transactions on Automatic Control, 54(4), 923-928, 2009.

  34. X. Zhang, A. Khadra, D. Yang and D. Li. Analysis and Design for Unified Exponential Stability of Three Different Impulsive T-S Fuzzy Systems. Chaos, Solitons & Fractals, 42, 1559-1566, 2009.

  35. X. Zhang, A. Khadra, D. Li and D. Yang. Impulsive Stability of Chaotic Systems Represented by T-S Model. Chaos, Solitons & Fractals, 41, 1863-1869, 2009.

  36. Y.X. Li and A. Khadra. Robust Synchrony and Rhythmogenesis in Endocrine Neurons Via Autocrine Regulations in Vitro and in Vivo. Bulletin of Mathematical Biology, 70, 2103-2125, 2008.

  37. A. Khadra and Y.X. Li. A model for the Pulsatile Secretion of Gonadotropin-Releasing Hormone from Synchronized Hypothalamic Neurons. Biophysical Journal, 91, 74-83, 2006.

  38. A. Khadra, X.Z. Liu and X. Shen. Impulsive Control and Synchronization of Spatiotemporal Chaos. Chaos, Solitons & Fractals, 26(2), 615-636, 2005.

  39. A. Khadra, X.Z. Liu and X. Shen. Impulsively Synchronizing Chaotic Systems with Delay and Applications to Secure Communication. IFAC Automatica, 41(9), 1491-1502, 2005.

  40. A. Khadra, X.Z. Liu and X. Shen. Application of Impulsive Synchronization to Communication Security. IEEE Transactions on Circuits and Systems-I: Fundamental Theory and Applications, 50(3), 341- 351, 2003.

  41. A. Khadra, X.Z. Liu and X. Shen. Robust Impulsive Synchronization and Application to Communication Security. Dynamics of Continuous, Discrete and Impulsive Systems, Series B, Applications & Algorithms, 10b(3), 403-417, 2003.