Ryan Alexander

PhD Student

ryan.alexander@mail.mcgill.ca

Ryan Alexander is originally from Edmonton, Alberta where he completed his BSc in Biological Sciences and Psychology at the University of Alberta. He then earned his MSc Neuroscience at the Ludwig-Maximilians-Universität in Munich, Germany working in Arthur Konnerth's lab supervised by Jana Hartmann. This work focused on the role of STIM proteins in mGluR-dependent signaling in cerebellar Purkinje neurons. He joined the Bowie Lab in January 2014 to pursue a growing interest in the inhibitory circuitry of the cerebellum, with a particular focus on firing dynamics of stellate cells and regulation of voltage-gated sodium channel properties.

Scholarships and Awards

2018

PRD Life Sciences Prize ($100)

2017

GREAT Award ($500)

2017

Faculty of Medicine Graduate Mobility Award ($2000)

2016

NSERC CGS-D Doctoral Fellowship ($70000)

2015

Savoy Foundation Studentship ($15000)

2014

Faculty of Medicine Internal Studentship ($12000)

2014

GEPROM Bourses de prestige ($9000)

2014

GREAT Travel Award ($500)

2014

Graduate Research Mobility Award in Medicine ($1400)

2010

Women and Children's Health Research Institute Summer Studentship ($5200)

2009

University of Alberta Undergraduate Excellence Scholarship ($750)

2009

Jason Lang Scholarship ($1000)

Publications

Alexander RPD, Mitry JSareen VKhadra A. Cerebellar stellate cell excitability is coordinated by shifts in the gating behavior of voltage-gated Na+ and A-type K+ channels. eNeuro. 2019 May 20; doi: https://doi.org/10.1523/ENEURO.0126-19.2019

Dawe GB, Kadir MF, Venskutonytė R, Perozzo AM, Yan Y, Alexander RPD, Navarrete C, Santander EA, Arsenault M, Fuentes C, Aurousseau MRP, Frydenvang K, Barrera NP, Kastrup JS, Edwardson JM, Bowie D. Nanoscale Mobility of the Apo State and TARP Stoichiometry Dictate the Gating Behavior of Alternatively Spliced AMPA Receptors. Neuron. 2019 Apr 30.

Alexander RPD, Concha L, Snyder TJ, Beaulieu C, Gross DW. Correlations between limbic white matter and cognitive function in temporal lobe epilepsy, preliminary findings. Front. Aging Neurosci. 2014 June;6:142. doi: 10.3389/fnagi.2014.00142

Hartmann J, Karl RM, Alexander RPD, Adelsberger H, Brill MS, Rühlmann C, Ansel A, Sakimura K, Baba Y, Kurosaki T, Misgeld T, Konnerth A. STIM1 controls neuronal Ca2+ signaling, mGluR1-dependent synaptic transmission and cerebellar motor behavior. Neuron. 2014 May 7;82(3):635-44.

Gong G, Alexander RPD, Shi F, Beaulieu C, Gross DW. Isolated febrile seizures are not associated with structural abnormalities of the limbic system. Epilepsy Res. 2012 Dec;102(3):216-20.