G protein-coupled signal transduction systems

Hébert Lab, Department of Pharmacology and Therapeutics, McGill University


PEOPLE

Darlaine Pétrin
MSc-Research Associate


Education:

M.Sc. Immunology, Université de Sherbrooke, Sherbrooke
B.Sc. Microbiology and Immunology, McGill University, Montréal

Research:

Being a research assistant in Terry’s lab provides the opportunity to work on a variety of projects related to G protein-coupled receptors (GPCR) and G protein complex assembly, trafficking and signalling. My involvement in the laboratory also involves some participation in general laboratory maintenance, and I occasionally act as a molecular biology resource.  

Selected Publications:

Richer M, David M, Villeneuve LR, Trieu P, Ethier N, Pétrin D, Mamarbachi AM, Hébert TE. GABA-B(1) Receptors are Coupled to the ERK1/2 MAP Kinase Pathway in the Absence of GABA-B(2) Subunits. J Mol Neurosci. 2008 Dec 4. [Epub ahead of print]  PubMed

Rebois R.V., Robitaille M, Pétrin D, Zylbergold P, Trieu P, Hébert TE. Combining protein complementation assays with resonance energy transfer to detect multipartner protein complexes in living cells. Methods (2008) Jul;45(3):214-8.

Guo H, Pétrin D, Zhang Y, Bergeron C, Goodyer CG, LeBlanc AC. Caspase-1 activation of caspase-6 in human apoptotic neurons. Cell Death Differ. (2006) 13 (2): 285-292.

Pétrin D, Turcotte S, Gilbert AK, Rola-Pleszczynski M, Stankova J. The anti-apoptotic effect of leukotriene B4 in neutrophils: a role for phosphatidylinositol 3-kinase, extracellular signal-regulated kinase and Mcl-1. Cell. Signalling (2006) 18 (4): 479-487.