G protein-coupled signal transduction systems

Hébert Lab, Department of Pharmacology and Therapeutics, McGill University


PEOPLE

Etienne Billard
Postdoctoral Researcher


After a B.Sc. in Chemistry/Biology and a M.Sc. in Drug Sciences at Université Blaise Pascal, (Clermont-Ferrand II, France), I  did a PhD in Biology under the supervision of Dr. David Chatenet (INRS, Laval), undertaking the synthesis and pharmacological characterisation of allosteric modulators of the urotensinergic system, using techniques such as peptide synthesis, binding, BRET-based biosensors and ex-vivo aortic contraction experiments. After my graduation in 2018, I worked with Dr. Jean-François Masson (UdeM, Montreal) on the development of a Surface-Enhanced Raman Spectroscopy (SERS)-based instrument to determine the composition of street-drug samples for harm-reduction purposes. I started postdoctoral research under Terry’s lab in early 2020, focusing on the mechanisms of action of LSD, a psychoactive substance with therapeutic value regarding the treatment of major depression and anxiety disorders. My research investigates potential interaction/hetero-oligomerization between AMPA and 5-HT2A, the receptor that mediates hallucinogenic effects of LSD.