Lawrence Joseph
Bayesian statistics
Professor
E-mail: lawrence.joseph@mcgill.ca
Telephone: +1 (514) 934-1934 ext: 44713
FAX: (514) 934-8293
Complete CV
Division of Clinical Epidemiology
McGill University Health Centre
Royal Victoria Hospital
687 Pine Avenue West
V Building, Room V2.10
Montreal, Quebec
Canada, H3A 1A1
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Bayesian Sample Size Change-point methods and applications Diagnostic testing
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Diagnostic testing in Genetics

We offer free technical support for each software package listed on this page.
Please do not hesitate to contact us.


ExposureAssessment
Exposure Assessment from continuous data in the absence of a gold standard test
Version 1.7, November 2012
A software package for estimating exposure probabilities in a series of subjects where one or more continuous test measurements relating to the exposure of interest are available for each subject
This package is an implementation of the methods presented in
Bayesian estimation of the probability of asbestos exposure from lung fiber counts
Weichenthal S, Joseph L, Bélisle P, Dufresne A
Biometrics 2010;66(2):603-612
Instructions
InstructionManual.pdf
Files
ExposureAssessment.zip
Install instructions
  1. ensure that you have Microsoft .Net Framework 1.1 installed (especially Windows Vista & Windows 7 users)
  2. download and unzip the zipped file (above)
  3. double-click setup.exe
  4. follow the instructions in file doc\InstallInstructions.html
    (or in its online version)
BayesDiagnosticTests
Estimation of Disease Prevalence and the Parameters of One, Two or Three Diagnostic Tests
Version 3.8.4, October 2012
A package to calculate Bayesian posterior distributions via Gibbs sampling for the prevalence of a disease, and sensitivity, specificity, positive and negative predictive values for each test used for that disease, in the absence of a gold standard; requires that the free software packages Winbugs and Perl be installed.
Replaces tt1, tt2 and tt3.
Instructions
InstructionManual.pdf
Files
BayesDiagnosticTests.zip
Install instructions
  1. ensure that you have Microsoft .Net Framework 1.1 installed (especially Windows Vista & Windows 7 users)
  2. download and unzip the zipped file (above)
  3. double-click setup.exe
  4. follow the instructions in file doc\InstallInstructions.html
    (or in its online version)
BayesContinuousDiagnosticTest
Estimation of Disease Prevalence and the Parameters of a Continuous Diagnotic Test and One or Two Dichotomous Diagnostic Test(s)
Version 3.6, October 2012
A software package to calculate marginal Bayesian posterior distributions via Gibbs sampling when data are available from a continuous diagnostic test and one or two dichotomous diagnostic test(s) in the absence of a gold standard; requires that the free software packages R, Winbugs and Perl be installed.
Instructions
InstructionManual.pdf
Files
BayesContinuousDiagnosticTest.zip
Install instructions
  1. ensure that you have Microsoft .Net Framework 1.1 installed (especially Windows Vista & Windows 7 users)
  2. download and unzip the zipped file (above)
  3. double-click setup.exe
  4. follow the instructions in file doc\InstallInstructions.html
    (or in its online version)
BayesLatentClassModels
A program for estimating diagnostic test properties and disease prevalence in the presence of possibly correlated tests
Version 1.10, December 2014
A software package for estimating diagnostic test properties and disease prevalence in the presence of possibly correlated tests in the absence of a gold standard; requires that the free software packages R and Perl be installed.
Instructions
InstructionManual.pdf
Files
BayesLatentClassModels.zip
Install instructions
  1. ensure that you have Microsoft .Net Framework 1.1 installed (especially Windows Vista & Windows 7 users)
  2. download and unzip the zipped file (above)
  3. double-click setup.exe
  4. follow the instructions in file doc\InstallInstructions.html
    (or in its online version)
PredictiveValues
Computation of Predictive Values when using One, Two or Three Diagnostic Tests
Version 1.7.2, February 2011
A program designed to convert information on a disease prevalence and one, two or three diagnosic tests into information on predictive values (i.e., on the probability for a patient of being truly positive given a series of diagnostic tests results)
Instructions
InstructionManual.pdf
Files
PredictiveValues.zip
Install instructions
  1. ensure that you have Microsoft .Net Framework 1.1 installed (especially Windows Vista & Windows 7 users)
  2. download and unzip the zipped file (above)
  3. double-click setup.exe
  4. follow the instructions in file doc\InstructionManual.pdf
Sample size determination for inference on prevalence or diagnostic test sensitivity or specificity
A package to calculate sample sizes based on highest posterior density intervals in the context of diagnostic testing in presence of one or two imperfect tests; requires that the free software packages R, Winbugs and Perl be installed.