Higher-Order Rhythms in an Ischemic 1-D Cable  

Rhythms of high-grade block in an ionic model of 
a strand of regionally
ischemic ventricular muscle

The full article
(J Theor Biol 249:29-45, 2007)
in Adobe Acrobat (PDF) format:
Download Article (1.6 MB)

                              Download Supplementary  Material I - "Ionic Model Equations" (94 KB)

                              Download Supplementary  Material II - "Additional Discussion" (123 KB)

 

Click on the links below to obtain QuickTime movies (.mov) of propagation down the one-dimensional cable at the indicated potassium concentration. 

Propagation is from left to right, and the time between individual frames is 10 ms.
Each movie loops, repeatedly showing the same one cycle of each periodic rhythm.

The figure numbers refer to the figures in the text of the paper.

(The QuickTime movie player can be downloaded from: www.apple.com/quicktime)

Length of Ischemic Segment = 1 cm

Figure         Rhythm        ([K+])

Fig. 1(A-C)     1:1     ( 5.400   mM)

Fig. 1(D-F)     1:1     (13.000  mM)

Fig. 2(A-C)     2:2     (13.173  mM)

Fig. 2(D-F)     2:1     (13.250  mM)

Fig. 3(A-C)     4:2     (13.437  mM)

Fig. 3(D-F)     4:1     (13.442  mM)

Fig. 4(A-C)     6:2     (13.472  mM)

Fig. 4(D-F)     6:1     (13.476  mM)

Fig. 5(A-C)     8:2     (13.4855 mM)

Fig. 5(D-F)     8:1     (13.487  mM)

Fig. 6(A-C)     2:0     (13.494  mM)

Fig. 6(D-F)     1:0     (13.745  mM)

Length of Ischemic Segment = 0.5 cm

Figure         Rhythm        ([K+])

Fig. 9(A-C)     2:1     (13.571  mM)

Fig. 9(D-F)     3:1     (13.574  mM)

Length of Ischemic Segment = 2.0 cm

Figure         Rhythm        ([K+])

none               4:1     (13.45 mM)

none               8:2     (13.46 mM)

none               4:1     (13.47 mM)