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Juliana C.
C.
Dallagnol
Postdoctoral Fellow |
I
completed my PhD in Pharmaceutical Sciences in 2018 at
the Federal University of Parana (Brazil) being awarded
with the “Thesis of the Year” in my Postgraduate
Program. I have participated on the “Science Without
Borders” Program in 2016, when I had the opportunity to
integrate a recognized research team at the Monash
University (Australia). My primary background is on
organic synthesis and medicinal chemistry. My research
has been focused on the design, synthesis and
pharmacological evaluation of novel bioactive compounds,
developing target-specific drug candidates for the
treatment of Alzheimer’s disease (targeting the
allosteric site of the M1 AChR). I’ve joined Terry’s lab
in 2019 with the challenge of developing caged-ligands
targeting the AT1R. Our goal is to improve the
“drug-likeness” of such compounds and, ultimately, to be
able to evaluate the therapeutic implications of
selectively targeting GPCRs located intracellularly. My
project will be a collaboration between Terry, David
Chatenet (INRS-Institut Armand-Frappier) and Bruce Allen
(Université de Montreal and Montreal Heart Institute).