Chloe Koens
Master's Student
Chloe was born and raised in Edmonton, Alberta, where she completed her BSc in Pharmacology at the University of Alberta in 2023. She was first introduced to the world of electrophysiology in Dr. Harley Kurata’s lab, where she investigated the biophysical and biochemical effects of a disease-linked mutant in Kv6.1 potassium channels. Over the course of multiple concurrent research projects aimed at elucidating a physiological role for Kv6.1, she became familiar with whole-cell patch clamp recording, site-directed mutagenesis, and biochemical analysis of ion channels. This work led Chloe to the Bowie lab, where she is investigating external pharmacological block in AMPA receptors. In her spare time, Chloe enjoys reading, running, and spending time with her cat.
Scholarships and Awards
2024-2025 |
Integrated Program in Neuroscience Internal Award ($15,000) |
Publications
Singh A., Zhorov B.S.*, Yanez-Guerra L.A.*, Aleotti A.*, Koens C.C.*, Yanartas C.D., Song Y., Miguez-Cabello F.J., Bowie D., and Senatore A. Evolution of iGluR ligand specificity, polyamine regulation, and ion selectivity inferred from a placozoan epsilon receptor. Commun Biol (2025). https://doi.org/10.1038/s42003-025-08402-3
Yasmine Bay, Federico Javier Miguez Cabello, Chloe C. Koens, Stine M. Fransten, Daryl S. Pickering, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Anders S. Kristensen, Derek Bowie, Jette Sandholm Kastrup. Crystal structure of the GluK1 ligand-binding domain with kainate and the full-spannnig positive allosteric modulator BPAM538. Journal of Struct Bio (2024). https://doi.org/10.1016/j.jsb.2024.108113