calcified bladder Y Keita June 8 2007.jpg (48900 bytes) Image: This 32 year old male emigrated from Cote d'Ivoire in 2006 and, in   2007 in Montreal, described intermittant hematuria of 8 years duration. He had been advised in Cote d'Ivoire, that this was due to his high intensity sports. He was otherwise well. A CT of the abdomen revealed a calcified bladder wall and a thickened  bladder wall at 12 - 2 o'clock.  The urologist noted three ulcers of the bladder mucosa wall and resected them. What was the diagnosis?
schisto bladder9.jpg (51567 bytes) schisto bladde6r.jpg (41628 bytes)

Quick Time video of  cystoscopy (requires latest, free, Quick Time 7 version)

 

 

 

 

 

 

 

 

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Image: The resected material was packed with degenerate schistosome eggs; no neoplasm was found. The urine had small numbers of calcified eggs. The schistosoma serology (ELISA-mixed S. hematobium and S. mansoni- National Parasit. Ref. Centre, Canada) was positive. Hemoglobin, WBC and periferal eosinophil levels were normal. He admitted to the treatment of a "bladder worms" at age 8, and to swimming in fresh water as a child. He was treated with Praziquantil and will be re-scoped in 4 months to once again look for squamous cell carcinoma which is ~15 times more frequent in individuals with S. hematobium infections. (IARC monographs Volume 61 1994)*. Bladder wall ulcers are a frequent finding in chronic S. hematobium infections.

HISTO-SCHIST 50X for web.jpg (468812 bytes)  

 

* International Agency for Research on Cancer, World Health Organization. Volume 61. Schistosomes, Liver Flukes and Helicobacter pylori. 1994

 

 

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