A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Dr. NancyFrasure-Smith, PhD
Social and behavioural science
Division of Social and Transcultural Psychiatry
1033 Pine Avenue West
Département de Psychiatrie, CHUM, Notre Dame
1560 Sherbrooke Street E.
Dr. Frasure-Smith received a PhD in Sociology from Johns Hopkins University and completed an NIMH postdoctoral fellowship in psychology at McGill University, where she is currently a Professor of psychiatry. She is also a Senior Research Associate at the Montreal Heart Institute, Adjunct Professor of nursing at McGill University, and a researcher at the Centre hospitalier de l’Université de Montréal (CHUM). She is a past President of the American Psychosomatic Society. Dr. Frasure-Smith and her colleague, Dr. François Lespérance, are known internationally for their work in bringing depression to the forefront of research in behavioural cardiology. They are examining the importance of depression and other psychological and social factors in the development and prognosis of cardiovascular disease, studying the physiological and behavioural links between depression and cardiovascular disease, and developing and evaluating interventions to change the impact of the depression and other psychological factors in cardiac patients. They recently carried out a multi-site, randomized trial of interpersonal psychotherapy and citalopram in patients with stable coronary artery disease that was funded by the Canadian Institutes of Health Research and have just finished conducting a trial of omega-3 fatty acid for depression. Dr . Frasure-Smith is also involved with researchers in the United States in the analysis of genetic and environmental data from two longitudinal cohort studies of patients with coronary heart disease and is a consultant on a South African study of genetic and environmental factors in hypertension and on a newly funded NHLBI (US) pilot study of depression treatment for cardiac patients. Recent publications have appeared in the Archives of General Psychiatry, JAMA, Circulation, and Brain, Behavior and Immunity.
Undergraduate: Social and Behavioural Sciences, The Johns Hopkins University
American Psychosomatic Society
Frasure-Smith N, Lespérance F. Depression and other psychological risks following myocardial infarction. Archives of General Psychiatry. 2003;60:627-636.
Frasure-Smith N, Lespérance F, Julien P. Major depression is associated with lower omega-3 fatty acid levels in patients with recent acute coronary syndromes. Biological Psychiatry. 2004;55: 891-896.
Lespérance F, Frasure-Smith N, Irwin M, Théroux P. The association between major depression, sICAM-1, interleukin-6 and CRP in patients with recent acute coronary syndromes. American Journal of Psychiatry. 2004;161:271-277.
Frasure-Smith N, Lespérance F. Recent evidence linking coronary heart disease and depression. Canadian Journal of Psychiatry. 2006;51:730-737.
Frasure-Smith N, Lespérance F, Irwin MR, Sauvé C, Lespérance J, Théroux P. Depression, C-reactive protein and two-year major adverse cardiac events in men after acute coronary syndromes. Biological Psychiatry. 2007;62:302-308.
Lespérance F, Frasure-Smith N, Koszycki D, Laliberté M-A, van Zyl LT, Baker B, Swenson JR, Ghatavi K, Abramson BL, Dorion P, Guertin M-C. Effects of citalopram and interpersonal psychotherapy on depression in coronary artery disease patients: the Canadian cardiac randomized evaluation of antidepressant and psychotherapy efficacy trial (CREATE). JAMA. 2007; 297(4):367-379.
Frasure-Smith N, Lespérance F. Depression and anxiety as predictors of two-year cardiac events in patients with stable coronary artery disease. Arch Gen Psychiatry. 2008;65(1):62-71.
McCaffery J, Duan QL, Frasure-Smith N, Barhdadi A, Lespérance F, Théroux P, Rouleau GA, Dubé MP. Genetic predictors of depressive symptoms in cardiac patients. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics). 2009;150B(3):381-8.
Frasure-Smith N, Lespérance F, Habra, M, Talajic M, Khairy P, Dorian P, Roy D for the Atrial Fibrillation and Congestive Heart Failure Investigators. Elevated depression symptoms predict long-term cardiovascular mortality in patients atrial fibrillation and heart failure. Circulation. 2009 Jul 14;120(2):134-140.
Frasure-Smith N, Lespérance F, Irwin MR, Talajic M, Pollock BG. The relationships among heart rate variability, inflammatory markers and depression in coronary heart disease patients. Brain, Behavior and Immunity. 2009;23:1140-1147.