A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 


Dr. MariaNatashaRajah, PhD
Associate Professor


Cognitive neurosciences
Prefrontal cortex
Aging


Douglas Mental Health Institute, A0117.1 CPC
6875 LaSalle Blvd
Montreal
Quebec
H4H 1R3
514-761-6131 ext. 2836
514-762-3028

natasha.rajah@douglas.mcgill.ca



Dr. Rajah is an Associate Professor in the Department of Psychiatry at McGill University and is researcher for the Geronto-Psychiatry Division at the Douglas Mental Health University Institute. In 2007 Dr. Rajah was awarded a New Investigator Award from the Institute of Aging at the Canadian Institute of Health Research for conducting functional and structural neuroimaging research on healthy aging and dementia. She currently holds operating grants from CIHR, NSER, and FRSQ for conducting both basic and clinically-based neuroimaging research. Basic Cognitive Neuroscience Research The basic cognitive neuroscience research in her lab involves using cutting-edge multivariate statistical tools to analyze neuroimaging data (i.e., fMRI data) and develop functional neural network models of learning, memory, and executive function in healthy young and older adults. Dr. Rajah is interested in using fMRI and parametric designs to understand the region-specific contributions of the prefrontal cortex to higher cognitive function. In addition, Dr. Rajah uses fMRI and MRI methods to determine how aging impacts structure-function associations in the prefrontal cortex and hippocampus and how this in turn may influence cognition in older healthy adults. Clinical Research The clinical research projects in Dr. Rajah’s lab cover a broad range of topics. She leads clinical teams on projects regarding falls prevention in geriatric units, multi-sensory therapy for dementia, and cognitive remediation for mild cognitive impairment at the DMHUI. In addition, she is currently using a combination of genetics, MRI, and fMRI methods to help identify early risk factors for the development of cognitive impairment with age. The basic theme of Dr. Rajah’s clinical research is early identification of cognitive decline in older adults and prevention of dementia.


Graduate: MA, Psychology, University of Toronto
Graduate: PhD, Psychology, University of Toronto

Postdoctoral: University of California, Berkeley





Rajah MN, Languay R, Valiquette L. Age-related changes in prefrontal cortex activity are associated with behavioural deficits in both temporal and spatial context memory retrieval in older adults. Cortex. Accepted July 2, 2009. In press.

Rajah MN, Bastianetto S, Bromley-Brits K, Cools R, D'Esposito M, Grady CL, Poirier J, Quirion R, Raz N, Rogaeva E, Song W, Pruessner J. Biological changes associated with healthy versus pathological aging: a symposium review. Ageing Res Rev. 2009 Apr;8(2):140-6.

Rajah MN, McIntosh AR. Age-related differences in brain activity during recency memory. Brain Research. 2008;1199:111-125.

Rajah MN, Ames B, D'Esposito M. Prefrontal contributions to domain-general executive control processes during temporal context retrieval. Neuropsychologia. 2008 Mar 7;46(4):1088-103.

Rajah MN, McIntosh AR. Dissociating prefrontal contributions during a recency memory task. Neuropsychologia. 2006;44(3):350-64.

Rajah MN, D'Esposito M. Region-specific changes in prefrontal function with age: a review of PET and fMRI studies on working and episodic memory. Brain. 2005 Sep;128(Pt 9):1964-83.

Rajah MN, McIntosh AR. Overlap in the functional neural systems involved in semantic and episodic memory retrieval. Journal of Cognitive Neuroscience. 2005;17(3):470-483.

McIntosh AR, Rajah MN, Lobaugh NJ. Functional connectivity of medial temporal lobe relates to learning and awareness. Journal of Neuroscience. 2003;23(26):6520-6528.

Grady CL, McIntosh AR, Rajah MN, Beig S, Craik FIM. The effects of age on the neural correlates of episodic encoding. Cerebral Cortex. 1999;9:805-814.

McIntosh AR, Rajah MN, Lobaugh NJ. Interactions of prefrontal cortex in relation to awareness in sensory learning. Science. 1999;284:1531-1533.