The McGill Physiology Virtual Lab

Exercise Physiology Laboratory

Background Information
 

You have learned about the interaction between the cardiovascular and respiratory systems during the lectures, and you are familiar with the measurements of respiratory and cardiovascular variables that you have recorded in the previous laboratories. You are also familiar with the theory of exercise physiology, working muscles and production of energy and oxygen consumption.

As you know, the respiratory system is responsible for gas exchange: the delivery of O2 from the atmosphere to the lungs and the removal of CO2 produced by the body to the atmosphere. The cardiovascular system is responsible for the delivery of O2 to all tissues of our body and the removal of CO2 from the tissues, and bringing CO2 back to the lungs. Therefore, in the maintenance of homeostasis, one system depends on the other. You also remember that the amount of O2 used and CO2 produced depend on the body metabolic rate, and that metabolic rate increases during exercise.

Oxygen uptake (VO2) increases in proportion to the increase in the exercise level, workload. More energy per unit time (power) is required to perform a heavier workload. Therefore, at greater workloads VO2 increases proportionately. However, above a certain level of workload, VO2 remains constant: VO2 reached its maximum. As you already know, this level of VO2 is called VO2MAX.

There are some factors that have to be considered in determining VO2 MAX:

  1. Posture should be upright. Horizontal position may decrease VO2 MAX by 30%.

  2. Muscle mass used in the exercise. Large muscles must be used. About 50% of the total muscle mass must be engaged in exercise before VO2 MAX can be achieved.

  3. Exercise duration. Both exercise duration and intensity must be great enough to elicit near maximal response of the cardiovascular system. A minimum of 3-4 min is required for each level of exercise, and the level of workload is increased progressively.

Prediction of Maximum Oxygen Uptake

VO2 MAX is exercise specific.VO2 MAX measured using an ergometer will be specific for cycling, which yields a lower value than running or cross-country skiing.

Therefore,  this method will underestimate the VO2 MAX by about 5-10%, both because of the muscle pain factor and the relatively small amount of muscle tissue involved in bicycling (upper body muscles not used much).

In this laboratory you will not make a direct measurement of VO2 MAX, which involves breathing through a 2-way-valve system and use of gas analyzer, but rather the value will be predicted from the measurements of your heart rate at different levels of workload. This method is frequently used since it has been established that heart rate increases in proportion to workload.

To continue with the next section: Cardio/CNS contribution, click here