Dr. Pejmun Haghighi Lab, Department of Physiology, McGill University

















Selected Publications:

Tsurudome K., Tsang K., Liao E. H., Yang J-S., Elazzouzi F., He T., Chishti A., Lnenicka G., Lai E. C. and Haghighi A. P. The Drosophila miR-310 cluster negatively regulates synaptic strength at the neuromuscular junction. (2010) Neuron, 68: 879-893.

Ball R. W., Warren-Paquin M., Tsurudome K., Liao E., Elazzouzi F., Cavanagh C., An B-S., Wang T-T., White J. H., and Haghighi A. P.. (2010) Retrograde BMP signaling controls synaptic growth at the NMJ by regulating Trio expression in motor neurons. Neuron, 66:536-49.

Merino-Hernandez C., Penney J., Aguire-Gonzalez M., Mujahedine M., Verheyen E., O’Connor M. and Haghighi A. P. (2009) Nemo kinase interacts with Mad to coordinate synaptic growth at the Drosophila NMJ. J Cell Biology, 185:713-725.

McCabe B. D., Hom S., Aberle H., Fetter R. D., Marques G., Haerry T. E., Wan H., O’Connor M. B., Goodman C. S. and Haghighi A. P. (2004). Highwire regulates presynaptic BMP signaling essential for synaptic growth. Neuron, 41:891-905.

Haghighi A. P., McCabe B. D., Fetter R. D., Palmer E.J., Hom S. and Goodman C. S. (2003). Retrograde control of synaptic transmission by postsynaptic CaMKII at the Drosophila neuromuscular junction. Neuron, 39:255-267.

Aberle H., Haghighi A. P., Fetter R. D., McCabe B. D, Magalh„es T.R., and Goodman C. S. (2002) wishful thinking Encodes a BMP Type II Receptor That Regulates Synaptic Growth in Drosophila. Neuron, 33:1-20.

DiAntonio, A. , Haghighi A. P. , Portman S. L. , Lee J. D., Amaranto A. M. & Goodman Corey S. (2001) Ubiquitination-dependent mechanisms regulate synaptic growth and function. Nature, 412:449-452.

Haghighi, A. P. and Cooper, E. (2000) A molecular link between inward rectification and calcium permeability of neuronal nicotinic acetylcholine alpha3beta4 and alpha4beta2 receptors. J Neurosci. 15:529-41.

Haghighi, A. P. and Cooper, E. (1998) Neuronal nicotinic acetylcholine receptors are blocked by intracellular spermine in a voltage-dependent manner. J. Neurosci., 18:4050-4062.