Ischaemic Arrhythmia Modelling

Spiral wave in a homogeneous sheet (external potassium concentration = 5.4 mM) induced by a two-pulse crossed-gradient protocol. This simulation is very similar to that shown in Fig. 3 of the article. The only difference is that the second stimulus is delivered at t=75 ms rather than at t=180 ms (the first stimulus is delivered at t=0 ms in both cases). Time between successive frames is 5 ms. First frame is at t=0 ms, last frame is at t=2495 ms.	Homog.mpg File size: 1,802 KB Number of frames: 500
Type I spiral wave induced by incremental pacing protocol in an inhomogeneous sheet (simulated ischaemic area with external potassium concentration = 20 mM). This is the first half of the simulation from which the frames shown in Figs. 5 and 6 of the article are taken (the second half is found in the file K20Type1b.mpg). Thirty-one stimuli are delivered, the first at t=0 ms, with the stimulation sequence being [BCL in ms (# of cycles at that BCL)]: 180(1), 150(1), 120(1), 100(1), 90(1), 80(5), 74(20). Time between successive frames is 5 ms. First frame is at t=0 ms, last frame is at t=2545 ms (since frames 151 and 212 are repeated - i.e. frame 152 = frame 151 and frame 213 = frame 212).	K20Type1a.mpg File size: 1,508 KB Number of frames: 512 (but 2 frames duplicated: see description at left)
Type I spiral wave induced by incremental pacing protocol in an inhomogeneous sheet (simulated ischaemic area with external potassium concentration = 20 mM) --- continued. This is the second half of the simulation from which the frames shown in Figs. 5 and 6 of the article are taken (the first half is found in the file K20Type1a.mpg). The first frame here follows on directly from the last frame of K20Type1a.mpg. Eleven stimuli are delivered at a BCL of 71 ms. Time between successive frames is 5 ms. First frame is at t=2550 ms, last frame is at t=4045 ms.	K20Type1b.mpg File size: 1043 KB Number of frames: 300
Type II spiral wave induced by incremental pacing protocol in an inhomogeneous sheet (simulated ischaemic area with external potassium concentration = 10.5 mM). This is the simulation from which the frames in Fig. 7 of the article are taken. Thirty stimuli are delivered, the first at t=0 ms, with the stimulation sequence being [BCL in ms (# of cycles at that BCL)]: 180(1), 150(1), 120(1), 100(1), 90(1), 80(5), 74(8), 71(11). Time between successive frames is 5 ms. First frame is at t=0 ms, last frame is at t=2690 ms.	K10p5Type2.mpg File size: 1,554 KB Number of frames: 539
Type I spiral wave induced by incremental pacing protocol in an inhomogeneous sheet (simulated ischaemic area with external potassium concentration = 10.5 mM). This is the simulation from which the frames in Fig. 8 of the article are taken. Thirty-two stimuli are delivered, the first at t=0 ms, with the stimulation sequence being [BCL in ms (# of cycles at that BCL)]: 180(1), 150(1), 120(1), 100(1), 90(1), 80(5), 74(8), 71(13). Time between successive frames is 5 ms. First frame is at t=0 ms, last frame is at t=2865 ms.	K10p5Type1.mpg File size: 1,688 KB Number of frames: 574
Type II spiral wave induced by incremental pacing protocol in an inhomogeneous sheet (simulated ischaemic area with external potassium concentration = 10.5 mM). This movie shows the end of a simulation in which the spiral wave makes nine rotations. This is the simulation from which the frames in Fig. 9 of the article are taken. Time between successive frames is 5 ms. Duration of part of simulation shown here is 845 ms.	K10p5multi.mpg File size: 504 KB Number of frames: 170
Irregular spiral-wave activity induced by incremental pacing protocol in an inhomogeneous sheet (simulated ischaemic area with external potassium concentration = 10.5 mM). This is the simulation from which the frames in Fig. 10 of the article are taken. Time between successive frames is 5 ms. Duration of part of simulation shown here is 995 ms.	K10p5irreg.mpg File size: 779 KB Number of frames: 200