Dr. Cuello's Research Laboratory


Department of Pharmacology and Therapeutics, McGill University


Lab Group

Simon Allard


  • L’Assomption, Quebec


  • B.Sc. McGill University, major in Anatomy and Cell Biology

  • Ph.D. candidate, McGill university, department of Pharmacology and Therapeutics, under the supervision of Dr. Ribeiro-da-Silva. I deposited my Ph.D. thesis in august 2010 and should be defending soon.

  • I am currently doing post doctoral work with Dr. Cuello.


Research Interests:

  • I have an interest in the biology of the cortical cholinergic system and how it is affected in aging and Alzheimer’s disease. I also have an interest in the changes in excitatory and inhibitory circuits of the cerebral cortex in normal aging and Alzheimer’s disease.

Current projects:

  • I am currently characterizing the relationship between intracellular and extracellular amyloid deposition, inflammation and the cortical cholinergic system in aged human brains with mild cognitive impairments and Alzheimer’s disease.

  • I will soon characterize the changes in cortical somatostanin positive inhibitory neurons in a transgenic rat model of the amyloid pathology.

  • Another new project will be to investigate the changes in excitatory and inhibitory currents in transgenic animals that display an early amyloid pathology in an attempt to understand the first physiological changes that lead to cognitive impairments.

Extracurricular Interests and Activities:

  • I enjoy Jogging and Yoga. I also like tennis and volleyball; I wish I played more often.

  • I must admit having a thing for Karaoke singing.

  • I easily get addicted to television series or to the discovery channel.


Contact information: simon.allard1@mail.mcgill.ca