Michael  Pollak


Oncology; Medicine

FRSQ Chercheur National
Alexander Goldfarb Chair in Medical Oncology

Jewish General Hospital
Room E763
3755 Côte Ste. Catherine Road
Montreal, QC H3T 1E2

Telephone: 514-340-8222 X 5530
E-mail: michael.pollak@mcgill.ca

Education: M.D., McGill University

Research Focus: Cancer Risk; Cancer Prevention; Hormones; Carcinogenesis; Animal Models; Insulin Resistance; Insulin-Like Growth Factors; Population Studies.

Recent Presentations:

10th Annual Stare-Hegsted lecture. Harvard University, School of Public Health and Department of Nutrition, Boston, May 2013, Visiting Professor and lecturer.

Are we winning the war on cancer? 1 Question * 100 Experts * 1 Answer. Lugano, Switzerland, October 2012: Invited Speaker, World Oncology Forum.

Keystone Symposium on Cancer Metabolism. Banff, February 2012.

Recent Publications:

Moiseeva O, Deschenes-Simard X, St-Germian E, Igelmann S, Huot G, Cadar AE, Bourdeau V, Pollak MN, Ferbeyre G.
Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation. Aging Cell 3: 489-98, 2013.

Pollak M,.
Targeting oxidative phosphorylation: why, when, and how. Cancer Cell 23: 263-4, 2013.

Leprivier G, Remke M, Rotblat B, Dubuc A, Mateo AR, Kool M, Agnihotri S, El-Naggar A, Yu B, Prakash Somasekharan S, Faubert B, Bridon G, Tognon CE, Mathers J, Thomas R, Li A, Barokas A, Kwok B, Bowden M, Smith S, Wu X, Korshunov A, Hielscher T, Northcott PA, Galpin JD, Ahern CA, Wang Y, McCabe MG, Collins VP, Jones RG, Pollak M, Delattre O, Gleave ME, Jan E, Pfister SM, Proud CG, Derry WB, Taylor MD, Sorensen PH.
The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation. Cell 5: 1064-79, 2013.

Pollak M.
The insulin receptor/insulin-like growth factor receptor family as a therapeutic target in oncology. Clini Cancer Res 18: 40-50, 2012.

Larsson O, Morita M, Topisirovic I, Alain T, Blouin MJ, Pollak M, Sonenberg N.
Distinct perturbation of the translatome by the antidiabetic drug metformin. Proc Natl Acad Sci USA. 2012 May 18. Epub ahead of print.

Pollak M.
Investigating metformin for cancer prevention and treatment: the end of the beginning. Cancer Discov 2: 778-90, 2012.