Philip  Branton


Oncology; Biochemistry

Gilman Cheney Professor of Biochemistry

Department of Biochemistry
McIntyre Medical Building
Room 701
3655 Promenade Sir William Osler
Montreal, QC H3G 1Y6

Telephone: (514) 398-8350

Education: Ph.D., M.Sc., B.Sc., University of Toronto

Research Focus: Adenoviruses; Apoptosis; Cell Death; Signal Transduction; Cell Cycle Regulation.

Recent Presentations:

CIHR Originals Meeting (Banff, AB) Feb 28-Mar 2 “Hot Topics in Cancer Research” (invited plenary talk)

IARC Meeting on Emerging Oncogenic Viruses, Madurna Italy, Jun 4-8 “A new role for the human Ad5 E4orf6/E1B55K E3 ubiquitin ligase complex and implications for human cancer“ (invited plenary talk)

DNA Tumor Virus Meeting, Madison WI Jul 21-26 “The human adenovirus type 5 E4orf4 protein targets two phosphatase regulators of the Hippo signaling pathway in inducing tumor cell-specific death” (plenary talk)

Recent Publications:

Sriskandarajah N, Blanchette P, Kucharski TJ, Teodoro JG, Branton PE. Analysis by Live Imaging of Effects of the Adenovirus E4orf4 Protein on Passage through Mitosis of H1299 Tumor Cells. J Virol. 2015 Apr 15;89(8):4685-9. doi: 10.1128/JVI.03437-14. Epub 2015 Feb 4.

Wimmer P, Berscheminski J, Blanchette P, Groitl P, Branton PE, Hay RT, Dobner T, Schreiner S.PML isoforms IV and V contribute to adenovirus-mediated oncogenic transformation by functionally inhibiting the tumor-suppressor p53. Oncogene. 2015 Mar 16. doi: 10.1038/onc.2015.63. [Epub ahead of print]

Gilson, T., C.Y Cheng, W.S. Hur, P. Blanchette and P.E. Branton. 2014. Analysis of the Cullin Binding Sites of the E4orf6 Proteins of Human Adenovirus E3 Ubiquitin Ligases. J. Virol. 88, 3885-3897.

Lu Y, Kucharski TJ, Gamache I, Blanchette P, Branton PE, Teodoro JG. 2014. Interaction of adenovirus type 5 E4orf4 with the nuclear pore subunit Nup205 is required for proper viral gene expression. J. Virol. 88, 13249-13259.