Education & Training
Cancer Epidemiology and Prevention
Special Topics in Epidemiology and Biostatistics: for oncology residents and fellows and graduate students in the health sciences.
- To review key concepts concerning carcinogenic mechanisms and pathogenesis with a view on formulating epidemiologic studies of cancer etiology and prognosis.
- To review the knowledge concerning the occurrence and the causes of human cancers and the means for preventing them.
- To examine the role of epidemiology in the study of cancer causes and prognostic factors and in the evaluation of preventive strategies.
Prerequisite: EPIB-606 or equivalent or permission of the instructor.
Session: Given every May at the Gerald Bronfman Centre. Check the McGill calendar for details.
Credits: Academic 2, CME: 26
Course Format: Interactive lectures and discussion of pertinent articles; exam with multiple-choice and essay-type questions.
Topics to be Covered
- Molecular and cellular basis of carcinogenesis (Mutational theory of carcinogenesis; Oncogenes and tumor suppressor genes; Carcinogenicity as a multistep, multifactorial process of long latency)
- Descriptive epidemiology (Burden of cancer: worldwide and Canada; International variations; Time trends in North America)
- Epidemiology vs. other approaches for evaluating carcinogenicity (Experimental and epidemiologic approaches; Defining causality: the perspective of regulatory agencies)
- Epidemiologic methods (Common framework for identifying causes and prognostic factors)
- Causes of cancer: Paradigms and murky areas (Lifestyle: Tobacco smoking; Biological environment: microbial agents; Dietary influences; Occupational and environmental exposures)
- Cancer prevention (Primary: reducing the impact of risk factors; Secondary: the role of screening; Tertiary: studying cancer survival and prognostic factors)
Coordinator: Eduardo L. Franco