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ANDRÉ VEILLETTE


Professor – University of Montreal

Associate Member – Department of Medicine, Division of Experimental Medicine

Contact information:

Telephone: (514) 987-5561
e-mail: andre.veillette@ircm.qc.ca
website: http://www.ircm.qc.ca/en/recherche/statique/unite10.html


Projects for Thesis Supervision:

1. Evaluation of the role of the adaptor molecule EAT-2 in macrophages and dendritic cells, using an EAT-2-deficient mouse generated in our laboratory.

2. Examination of the mechanism by which SAP, a small adaptor molecule mutated in X-linked lymphoproliferative disease in humans, regulates immune responses.

3. Characterization of the role and mechanism of action of SLAM family receptors in immune cells.


Recent Publications:

Veillette, A., Zhang, S., Shi, X., Dong, Z., Davidson, D. and Zhong, M.-C.
SAP expression in T cells, not in B cells, is required for humoral immunity. Proc. Natl. Acad. Sci. In Press, 2008.

Veillette, A., Dong, Z. and Latour, S. (2007)
Consequence of the SLAM-SAP signaling pathway in innate-like and conventional lymphocytes. Immunity 27: 698-710.

Davidson, D., Schraven, B. and Veillette, A. (2007)
PAG-associated FynT regulates calcium signaling and promotes anergy in T lymphocytes. Mol. Cell. Biol. 27: 1960-1973.