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Contact
information:
Telephone: (514)
340-8222, ext. 4847
e-mail address:
andrew.mouland@mcgill.ca
website:
www.mcgill.ca/microimm/department/associates/mouland/
Projects for Thesis
Supervision:
Students will use molecular,
cellular, biophysical and biochemical methods in combination with
advanced microscopy techniques to understand:
1. Countermeasures elicited by
HIV-1 to evade host cell RNA quality control and surveillance
machineries (currently a focus on UPF and SMG host cell proteins);
2. Countermeasures elicited by
HIV-1 to evade host stress responses (currently a focus on the role of
HIV-1 dependent staufen1 ribonucleoproteins, stress granules, processing
bodies (P Bodies) and other types of ribonucloprotein complexes).
Recent
Publications:
Mouland, A.J. and Milev, M. (2011)
Role of dynein in viral pathogenesis. In: " Dyneins", edited by S.M.
King, Academic Press, London, Waltham, San Diego, pp. 560-583.
Monette, A., Pante, N. and Mouland, A.J. (2011)
Dramatic changes to the nuclear envelope proteome induced in HIV-1
infected T-cells. J. Cell. Biol. 193: 619-631.
Lund, N., Milev, M.P., Wong, R., Sanmuganantham,
T., Woolaway, K., Chabot, B., Abou Elela, S., Mouland, A.J. and
Cochrane, A. (2012)
A role for hnRNP D in regulating HIV-1 gene expression. Nucl. Acids
Res., doi: 10,1093/nar/gkr1238.
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