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Contact
information:
Telephone: (514) 398-2762
e-mail address:
serge.lemay@mcgill.ca
website:
http://www.mcgill.ca/hcru/faculty/lemay/
Projects for Thesis
Supervision:
1. Role of Eph/ephrin signaling in
ischemia-reperfusion injury.
2. Mechanism of EphA2 action and
transcriptional regulstion.
3. Role of the adapter protein Dok-4 in
epithelial cell signaling.
Recent
Publications:
Baldwin, C., Bedirian, A., Li,
H., Takano, T. and Lemay, S. (2007)
Identification of Dok-4b, a Dok-4 splice variant with enhanced
inhibitory properties. Biochem. Biophys. Res. Comm. 354: 783-788.
Baldwin, C., Chen, Z.W., Bedirian, A., Yokota,
N., Nasr, S.H., Rabb, H. and Lemay, S.
(2006)
Upregulation of EphA2 during in vivo and in vitro renal
ischemia-reperfusion injury: role of Src kinases. Am. J. Physiol. 291:
F960-F971.
Bederian, A., Balwin, C., Abe, J., Takano, T.
and Lemay, S. (2004)
PH and PTH domain-dependent membrane association and tyrosine
phosphorylation of Dok-4, an inhibitory adapter molecule expressed in
epithelial cells. J. Biol. Chem. 279: 19335.
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