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Contact
information:
Telephone: (514) 934-1934, ext.
34401
e-mail address:
john.dibattista@mcgill.ca
website:
Projects for Thesis
Supervision:
1. Identification of signaling scaffolds
proteins integrated in the prostaglandin EP4 receptor system in
inflammatory cells.
2. Identification of novel RNA binding proteins
using genomic and proteomic approaches; elucidation of novel
post-transcriptional and translational mechanisms controlling oncogene
and early response gene expression.
3. Identification of auto-antigens in
rheumatoid arthritis patients using novel genomic and proteomic
approaches.
Recent
Publications:
Cybulsky, A.V., Takano, T., Papillon, J., Hao, W.,
Mancini, A., Di Battista, J.A.
and Cybulsky, M. (2007)
The 3'-untranslated region of the Ste20-like kinase SLK regulates SLK
expression. Am. J. Physiol. Renal Physiol. 292: F845-F852.
Mancini, A., Jovanovic, D, He, Q.W. and
Di Battista, J.A. (2007)
Site-specific proteolysis of cyclooxygenase-2: A putative step in
inflammatory prostaglandin E(2) biosynthesis. J. Cell. Biol. 101:
425-441.
Faour, W.H., He, Q.W., Mancini, A., Jovanovic, D.,
Antoniou, J. and Di Battista, J.A.
(2006)
Prostaglandin E2 stimulates p53 transactivational activity through
specific serine 15 (Ser15) phosphorylation in human synovial fibroblasts
(HSF): Role in suppression of c/EBP/NF-kB mediated Erk kinase kinase
(MEKK)1-induced MMP-1 expression. J. Biol. Chem. 281: 19849-19860.
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