Peer-Reviewed Publications (1997 - )
*First author was student/trainee under my supervision†First author was student/trainee under my co-supervision
Original Research Contributions
1. Rao S, Pai M, Iyanar A, Joseph A. Sanitation for rural communities: first win the people's support. World Health Forum 1997, Vol 18:262-265.
2. Pai M, Zachariah A, Rose W, Satyajit S, Verghese S, Joseph A. Malaria and migrant labourers: socio-epidemiological inquiry. Economic and Political Weekly, Vol XXXII, No 16, 1997.
3. Pai M, Kang G, Ramakrishna BS, Venkataraman A, Muliyil JP. An epidemic of diarrhoea in south India caused by enteroaggregative Escherichia coli. Indian J Med Res 1997;106:7-12.
4. Abraham M, Pai M, Kang G, Asokan GV, Magesh SR, Bhattacharji S, Ramakrishna BS. An outbreak of food poisoning in Tamil Nadu associated with Yersinia enterocolitica. Indian J Med Res 1997;106:465-468.
5. Pai M, Sundaram P, Radhakrishnan KK, Thomas K, Muliyil JP. Hepatitis B immunization coverage and awareness in middle and upper class population in Chennai City. Indian Pediatrics 1998; 35:922-23.
6. Alaganantham TP, Pai M, Vaidehi T, Thomas J. Seroepidemiology of Helicobacter pylori infection in an urban, upper-class population in Chennai City. Indian J Gastroenterology 1999;18(2):66-68.
7. Pai M, Sundaram P, Radhakrishnan K K, Thomas K, Muliyil JP. A high rate of caesarean sections in an affluent section of Chennai City: Is it cause for concern? Natl Med J India 1999;12(4)156-158.
8. Rajaram R, Rajagopalan RE, Pai M, Mahendran S. Survival after cardiopulmonary resuscitation in an urban Indian hospital. Natl Med J India 1999;12(2):51-55.
9. Rajagopalan RE, Chandrasekaran S, Pai M, Rajaram R, Mahendran S. Pre-hospital delay in acute myocardial infarction in an urban Indian hospital: a prospective study. Natl Med J India 2001;14(1):8-12.
10. Santhanam I, Pai M, Kasturi K, Radhamani MP. Mortality after admission in the pediatric emergency department: a prospective study from a referral, children's hospital in south India. Ped Crit Care Med 2002;3:358-363.
11. Singh M, Pai M, Kalantri SP. Accuracy of perception and touch for detecting fever in adults: a hospital-based study from a rural, tertiary hospital in Central India. Trop Med & Int Health 2003;8:408-14. [Link]
12. †Indra R, Patil SS, Joshi R, Pai M, Kalantri SP. Accuracy of physical examination in the diagnosis of hypothyroidism: a cross-sectional, double-blind study. J Postgrad Med 2004;50(1):7-11. [Link]
13. †Joshi R, Singh A, Jajoo N, Pai M, Kalantri SP. Accuracy and reliability of palpation and percussion for detecting hepatomegaly: a rural hospital-based study. Indian J Gastroenterol 2004;23:171-74. [Link]
14. †Patil SS, Joshi R, Gupta G, Reddy MVR, Pai M, Kalantri SP. Risk factors for acute myocardial infarction in a rural population in central India: a hospital-based case-control study. Natl Med J India 2004;17:189-94. [Link]
15. Pai M, Gokhale K, Joshi RJ, Dogra S, Kalantri SP, Mendiratta DK, Narang P, Daley CL, Granich RM, Mazurek GH, Reingold AL, Riley LW, Colford, JM. Mycobacterium tuberculosis infection in health care workers in rural India: comparison of a whole-blood, interferon-g assay with tuberculin skin testing. JAMA 2005;293:2746-55. [Link]
16. †Geetadevi Y, Joshi R, Pai M, Kalantri SP. Simple clinical predictors of brain lesions in patients with impaired consciousness: a cross sectional study from a rural, tertiary hospital in central India. Clin Neurol Neurosurg 2005 Dec;108(1):25-31. [Link]
17. Pai M, Joshi R, Dogra S, Mendiratta DK, Narang P, Kalantri SP, Reingold AL, Colford, JM, Riley LW, Menzies D. Serial testing of health care workers for tuberculosis using interferon-g assay. Am J Respir Crit Care Med 2006; 174 349-355. [Link]
18. Pai M, Joshi R, Dogra S, Mendiratta DK, Narang P, Dheda K, Kalantri SP. Persistently elevated T cell interferon-g responses after treatment for latent tuberculosis infection among health care workers in India: a preliminary report. J Occup Med Toxicol 2006;1:7. [Link]
19. Farhat M, Greenaway C, Pai M, Menzies D. False-positive tuberculin skin tests: what is the absolute effect of BCG and non-tuberculous mycobacteria? Int J Tuberc Lung Dis 2006;10(11):1192-1204. [Link]
20. †Dogra S, Narang P, Mendiratta DK, Chaturvedi P, Reingold AL, Colford, JM, Riley LW, Pai M. Comparison of a whole-blood, interferon-g assay with tuberculin skin testing for the detection of tuberculosis infection in hospitalized children in rural India. J Infect 2007;54:267-76. [Corresponding author]. [Link]
21. Kalantri SP, Joshi R, Lokhande T, Singh A, Morgan M, Colford JM, Pai M. Accuracy and reliability of physical signs in the diagnosis of pleural effusion. Resp Med 2007;101:431-38. [Corresponding author]. [Link]
22. Pai M, Joshi R, Banypdophadyay M, Narang P, Dogra S, Taksande B, Kalantri S. Sensitivity of a whole-blood interferon-gamma assay among patients with pulmonary tuberculosis and variations in T cell responses during anti-tuberculosis treatment. Infection 2007;35:98-103. [Link]
23. Pai NP, Joshi R, Dogra S, Taksande B, Kalantri SP, Pai M, Narang P, Tulsky JP, Reingold AL. Evaluation of Diagnostic Accuracy, Feasibility and Client Preference for Rapid Oral Fluid-Based Diagnosis of HIV Infection in Rural India. PLoS ONE 2007;2(4):e367. [Link]
24. Dheda K, Pooran A, Pai M, Miller RF, Lesley K, Booth H, Scott GE, Akbar A, Zumla A, Rook GA. Interpretation of M. tuberculosis antigen-specific IFN-g release assays (T-SPOT.TB) and factors that may modulate test results. J Infect 2007;55:169-73. [Link]
25. Birkner MD, Kalantri SP, Solao V, Badam P, Joshi R, Goel A, Pai M, Hubbard AE. Creating Diagnostic Scores using Data-Adaptive Regression: An application to prediction of 30-day Mortality among Stroke Victims in a Rural Hospital in India. Therapeutics and Clinical Risk Management 2007;3(3):475-84. [Link]
26. †Joshi R, Patil S, Kalantri SP, Schwartzman K, Menzies D, Pai M. Prevalence of abnormal radiological findings in health care workers with latent tuberculosis infection and correlations with T cell immune response. PLoS ONE 2007;2(8):e805. [Corresponding author]. [Link]
27. †Anandharaman V, Joshi R, Goswami K, Dogra S, Moodie EM, Reddy MVR, Kalantri SP, Schwartzman K, Behr M, Menzies D, Pai M. Short-term reproducibility of a whole-blood interferon-gamma release assay for tuberculosis infection: a pilot study from India. PLoS ONE 2008;3(3):e1850. [Corresponding author]. [Link]
28. Menzies D, Gardiner G, Farhat M, Greenaway C, Pai M. Thinking in three dimensions: A web-based algorithm to aid the interpretation of the tuberculin skin test results. Int J Tuberc Lung Dis 2008;12(5):498-505. [Link]
29. Pai NP, Barick R, Tulsky JP, Shivkumar PV, Cohan D, Kalantri S, Pai M, Klein MB, Chhabra S. Impact of round-the-clock, rapid oral fluid HIV testing of women in labor in rural India. PLoS Med 2008;5(5):e92. [Link]
30. **Pai M, **Dendukuri N, Wang L, Joshi R, Kalantri S, Rieder HL. Improving the estimation of TB infection prevalence using T-cell-based assay and mixture models. Int J Tuberc Lung Dis 2008;12(8):895-902. [**joint first authors][Link]
31. Pai M, Joshi R, Dogra S, Zwerling AA, Gajalakshmi D, Goswami K, Reddy MVR, Kalantri S, Hill PC, Menzies D, Hopewell PC. T-cell assay conversions and reversions among household contacts of TB patients in rural India. Int J Tuberc Lung Dis 2009;13(1):84-92. [Link]
32. Pai NP, Joshi R, Moodie EM, Taksande B, Kalantri S, Pai M, Tulsky JP, Reingold A. Profile of adults seeking voluntary HIV testing and counseling in rural Central India: results from a hospital-based study. AIDS Care 2009;21:294-300. [Link]
33. †van Zyl Smit R, Pai M, Peprah K, Meldau R, Kieck J, Juritz J, Badri M, Zumla A, Bateman E, Dheda K. Within-subject variability and boosting of T cell IFN-γ responses following tuberculin skin testing. Am J Resp Crit Care Med 2009;180:49-58. [Link]
34. Daley P, Michael JS, Kalaiselvan S, Latha A, Mathai D, John KR, Pai M. A Pilot Study of Short-duration Sputum Pretreatment Procedures for Optimizing Smear Microscopy for Tuberculosis. PLoS ONE 4(5): e5626. [Corresponding author]. [Link]
35. Daley P, Michael JS, Hmar P, Latha A, Chordia P, Mathai D, John KR, Pai M. Blinded Evaluation of Commercial Urinary Lipo-Arabinomannan for Active Tuberculosis: A pilot study. Int J Tuberc Lung Dis 2009;13(8):989-995. [Corresponding author]. [Link]
36. Oxlade O, Schwartzman K, Behr MA, Benedetti A, Pai M, Heymann J, Menzies D. Global tuberculosis trends - a reflection of changes in TB control or in population health? Int J Tuberc Lung Dis 2009 Oct;13(10):1238-46. [Link]
37. †Fontela PS, Pai NP, Schiller I, Dendukuri N, Ramsay A, Pai M. Quality and Reporting of Diagnostic Accuracy Studies in TB, HIV and Malaria: Evaluation Using QUADAS and STARD Standards. PLoS ONE 2009;4(11): e7753. [Corresponding author][Link]
38. Sarojini JM, Daley P, Kalaiselvan S, Latha A, Mathai D, John KR, Pai M. Diagnostic Accuracy of Microscopic Observation Drug Susceptibility assay (MODS): A Pilot Study from India. Int J Tuberc Lung Dis 2010;14(4):482-88. [Senior author] [Link]
39. Dheda K, Davids V, Lenders L, Roberts T, Meldau R, Ling D, Brunet L, van-zyl Smit R, Peter J, Green C, Badri M, Sechi L, Sharma S, Hoelscher M, Dawson R, Whitelaw A, Blackburn J, Pai M, Zumla A. Clinical Utility of a Commercial LAM-ELISA Assay for TB Diagnosis in HIV-Infected Patients Using Urine and Sputum Samples. PLoS One 2010;5(3): e9848. [Link]
40. Oxlade O, Schwartzman K, Pai M, Heymann J, Benedetti A, Royce S, Menzies D. Predicting outcomes and drug resistance with standardized treatment of active TB. Eur Resp Journal 2010;36: 870-877. [Link] [Link]
41. Christopher DJ, Daley P, Armstrong L, James P, Gupta R, Premkumar B, Michael JS, Radha V, Zwerling A, Schiller I, Dendukuri N, Pai M. Tuberculosis infection among young nursing trainees in South India. PLoS One 2010;5(4): e10408. PLoS One 2010;5(4): e10408. [Corresponding author] [Link]
42. Oxlade O, Schwartzman K, Benedetti A, Pai M, Heymann J, Menzies D. Developing a tuberculosis transmission model that accounts for changes in population health. Med Des Making June 2010; 31:53-68. [Link]
43. Fontela P, Platt RW, Rocher I, Frenette C, Moore D, Fortin E, Buckeridge D, Pai M, Quach C. Surveillance Provinciale des Infections Nosocomiales (SPIN) Program: Implementation of a mandatory surveillance program for central line-associated bloodstream infections. Am J Infect Control 2011 Jan 20. [Epub ahead of print].
44. O'Donnell MR, Jarand J, Loveday M, Padayatch N, Zelnick J, Werner L, Naidoo N, Master I, Osburn G, Kvasnovsky C, Shean K, Pai M, Van der Walt M, Horsburgh CR, Dheda K. High Incidence of Hospital Admissions for Multidrug Resistant and Extensively Drug Resistant Tuberculosis among South African Health Care Workers. Annals Int Med 2010;153:516-522.
45. Shenai S, Minion J, Vadwai V, Tipnis T, Shetty S, Salvi A, Udwadia Z, Pai M, Rodrigues C. Evaluation of LED based fluorescence microscopy for the detection of mycobacteria in a TB endemic region. Int J Tuberc Lung Dis 2011;15(4):483-8.
46. *Brunet L, Pai M, Davids V, Ling D, Paradis G, Lenders L, Meldau R, van-zyl Smit RV, Calligaro G, Allwood B, Dawson R, Zumla A, Dheda K. High prevalence of smoking among patients with suspected tuberculosis in South Africa. Eur Resp J 2010 (published ahead of print).
47. *Zwerling A, Behr M, Varma A, Brewer T, Menzies D, Pai M. The BCG World Atlas: A Database of Global BCG Vaccination Policies and Practices. PLoS Med 2011;8(3): e1001012.
48. *Ling D, Pai M, V. Davids, L. Brunet, L. Lenders, R. Meldau, G. Calligaro, B. Allwood, R. van Zyl-Smit, J. Peter, E. Bateman, R. Dawson, and K. Dheda. Are interferon-γ release assays useful for active tuberculosis in a high-burden setting? Eur. Respir. J. published 24 February 2011, 10.1183/09031936.00181610
49. Moyo S, Isaacs F, Gelderbloem S, Verver S, Hawkridge A, Hatherill M, Tameris M, Workman L, Pai M, Hussey G, Hanekom W, Mahomed H. Tuberculin skin test and QuantiFERON assay in young children investigated for tuberculosis in South Africa. Int J Tuberc Lung Dis (in press).
50. Joshi R, Narang U, Zwerling A, Jain D, Jain V, Kalantri SP, Pai M. Predictive value of latent TB tests in Indian health-care workers: a cohort study. Eur Respir J 2011;38(6):1475‐77.
51. *Minion J, Shenai S, Vadwai V, Tipnis T, Greenaway C, Menzies D, Ramsay A, Rodrigues C, Pai M. Re: Fading of auramine-stained mycobacterial smears and implications for external quality assurance. J Clin Micro 2011;49(5):2024-26.
52. Theron G, Peter J, Pai M, Dheda K. Evaluation of the Xpert® MTB/RIF assay for the diagnosis of pulmonary tuberculosis in a high HIV prevalence setting. Am J Resp Crit Care Med 2011; 184(1):132‐40.
53. Fontela P, Platt RW, et al. Epidemiology of Central Line-Associated Bloodstream Infections in Quebec Intensive Care Units: A 6-year Review. Am J Infect Control 2011 (in press).
54. Whitelaw A, Peter J, Sohn H, Viljoen D, Theron G, Badri M, Davids V, Pai M, Dheda K. Comparative cost and performance of LED-microscopy in HIV-TB co-infected patients. Eur Respir J 2011;38 1393‐1397.
55. Grenier J, Pinto L, Nair D, Steingart KR, Dowdy D, Ramsay A, Pai M. Widespread use of serological tests for tuberculosis: data from 22 high-burden countries. European Respir J 2012;39(2):502‐505.
56. Rangaka MX, Gideon H, Wilkinson K, Pai M, Mwansa‐Kambafilwe J, et al. Interferon release does not add discriminatory value to smear‐negative HIV–tuberculosis algorithms. Eur Respir J 2012; 39: 163–171.
57. Dowdy D, Cattamanchi A, Steingart KR, Pai M. Is Scale‐Up Worth It? Challenges in Economic Analysis of Diagnostic Tests for Tuberculosis. PLoS Med 2011; 8(7): e1001063.
58. Dowdy D, Steingart KR, Pai M. Serological Testing versus Other Strategies for Diagnosis of Active Tuberculosis in India: A Cost‐Effectiveness Analysis. PLoS Med 2011;8(8): e1001074. 59. *Minion J, Pai M, Menzies D, Ramsay A, Greenaway C. Comparison of LED and conventional fluorescence microscopy for detection of acid fast bacilli in a low‐incidence setting. PLoS One 2011; 6(7): e22495.
60. Christopher DJ, James P, Daley P, Armstrong L, Isaac BT, Balmugesh T, Premkumar B, Zwerling A, Pai M. High annual risk of tuberculosis infection among nursing students in South India: a cohort study. PLoS One 2011; 6(10): e26199.
61. Jaroslawski S, Pai M. Why are tuberculosis serological tests widely used in the Indian private healthcare sector? A root‐cause analysis. J Epi Global Health 2012 (in press).
Meta-Analyses and Systematic Reviews
1. Pai M, Flores LL, Pai N, Hubbard A, Riley LW, Colford JM. Diagnostic accuracy of nucleic acid amplification tests for tuberculous meningitis: a systematic review and meta-analysis. Lancet Infect Dis 2003;3:633-43. [Link]
2. Pai M, Flores LL, Hubbard A, Riley LW, Colford JM. Nucleic acid amplification tests in the diagnosis of tuberculous pleuritis: a systematic review and meta-analysis. BMC Infect Dis 2004;4:6. [Link]
3. Pai M, Riley LW, Colford JM. Interferon-g assays in the immunodiagnosis of tuberculosis: a systematic review. Lancet Infect Dis 2004;4:761-76. [Link]
4. Gorman JD, David-Vaudey E, Pai M, Lum RF, Criswell LA. Particular HLA-DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis. Arthritis Rheum 2004 Nov;50(11):3476-84.
5. Gorman JD, David-Vaudey E, Pai M, Lum RF, Criswell LA. Lack of association of the HLA-DRB1 shared epitope with rheumatoid nodules: an individual patient data meta-analysis of 3,272 Caucasian patients with rheumatoid arthritis. Arthritis Rheum 2004 Mar;50(3):753-62.
6. Pai M, Kalantri SP, Pascopella L, Riley LW, Reingold AL. Bacteriophage-based assays for the rapid detection of rifampicin resistance in Mycobacterium tuberculosis: a meta-analysis. J Infect 2005;51:175-187. [Link]
7. *Kalantri SP, Pai M, Pascopella L, Riley LW, Reingold AL. Bacteriophage-based tests for the detection of Mycobacterium tuberculosis in clinical specimens: a systematic review and meta-analysis. BMC Infect Dis 2005;5:59. [Link]
8. *Morgan M, Kalantri SP, Flores L, Pai M. A commercial line probe assay for the rapid detection of rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis. BMC Infect Dis 2005;5:62. [Corresponding author] [Link]
9. †Flores LL, Pai M, Colford JM, Riley LW. In-house nucleic acid amplification tests for the detection of Mycobacterium tuberculosis in sputum specimens: a meta-analysis. BMC Microbiology 2005;5:55. [Link]
10. Hwang J, Bitarakwate E, Pai M, Reingold A, Rosenthal PJ, Dorsey D. Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for uncomplicated malaria: a systematic review. Trop Med Int Health 2006; 11(6):789-799. [Link]
11. *Steingart KR, Henry M, Ng N, Hopewell PC, Ramsay A, Cunningham J, Urbanczik R, Perkins M, Aziz MA, Pai M. Fluorescence versus conventional sputum smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis 2006;6:568-79. [Corresponding author] [Link]
12. *Steingart KR, Ng N, Henry M, Hopewell PC, Ramsay A, Cunningham C, Urbanczik R, Perkins M, Aziz MA, Pai M. Sputum processing methods to improve the sensitivity of smear microscopy for tuberculosis: a systematic review. Lancet Infect Dis 2006;7:664-74. [Corresponding author]. [Link]
13. *Joshi R, Reingold A, Menzies D, Pai M. Tuberculosis among health care workers in low and middle income countries: a systematic review. PLoS Medicine 2006;3(12):e494. [Corresponding author]. [Link]
14. Menzies D, Pai M, Comstock G. New tests for diagnosis of latent tuberculosis infection: areas of uncertainty and recommendations for research. Ann Intern Med 2007;146:340-354. [Link]
15. Bates MN, Khalakdina A, Pai M, Chang L, Lessa F, Smith KR. The risk of tuberculosis from exposure to tobacco smoke: a systematic review and meta-analysis. Arch Intern Med 2007;167:335-342. [Link]
16. Mase S, Ramsay A, Ng N, Henry M, Hopewell PC, Cunningham C, Urbanczik R, Perkins M, Aziz MA, Pai M. Yield of serial sputum specimen examinations in the diagnosis of pulmonary tuberculosis: a systematic review. Int J Tuberc Lung Dis 2007;11(5):484-95. [Link]
17. Steingart KR, Henry M, Laal S, Hopewell PC, Ramsay A, Menzies D, Cunningham C, Weldingh K, Pai, M. Commercial serological antibody detection tests for the diagnosis of pulmonary tuberculosis: a systematic review. PLoS Medicine 2007;4(6):e202. [Corresponding author]. [Link]
18. Steingart KR, Henry M, Laal S, Hopewell PC, Ramsay A, Menzies D, Cunningham C, Weldingh K, Pai M. A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Thorax 2007; 62:911-918. [Corresponding author]. [Link]
19. Daley P, Thomas S, Pai M. Nucleic acid amplification tests for the diagnosis of tuberculous lymphadenitis: a meta-analysis. Int J Tuberc Lung Dis 2007;11(11): 1166-1176. [Link]
20. *Ling D, Flores L, Riley L, Pai M. Commercial Nucleic-Acid Amplification Tests for Diagnosis of Pulmonary Tuberculosis in Respiratory Specimens: Meta-Analysis and Meta-Regression. PLoS ONE 2008;3(2):e1536. [Corresponding author]. [Link]
21. †Morrison J, Pai M, Hopewell PC. Tuberculosis and latent tuberculosis infection in close contacts of people with pulmonary tuberculosis in low-income and middle-income countries: a systematic review and meta-analysis. Lancet Infect Dis 2008;8(6):359-68. [Link]
22. Pai M, Zwerling A, Menzies D. Systematic Review: T-cell Based Assays for the Diagnosis of Latent Tuberculosis Infection-An Update. Ann Intern Med 2008;149:177-184. [Link]
23. Lew W, Pai M, Oxlade O, Martin D, Menzies D. Initial drug resistance and tuberculosis treatment outcomes: systematic review and meta-analysis. Ann Intern Med 2008;149:123-134. [Link]
24. *Ling D, Zwerling A, Pai M. GenoType MTBDR assays for diagnosis of multidrug-resistant tuberculosis: a meta-analysis. Eur Resp Journal 2008;32:1165-74. [Corresponding author]. [Link]
25. Steingart KR, Dendukuri N, Henry M, Schiller I, Nahid P, Hopewell PC, Ramsay A, Pai M, Laal S. Performance of Purified Antigens for Serodiagnosis of Pulmonary Tuberculosis: a Meta-analysis. Clin Vacc Immunol 2009;16(2):260-76. [Link]
26. Menzies D, Benedetti A, Paydar A, Royce S, Pai M, Burman W, Vernon A, Liendardt C. Standardized treatment of active tuberculosis in patients with previous treatment and/or with mono-resistance to isoniazid: a systematic review and meta-analysis. PLoS Med 2009;6(9):e1000150.
27. Menzies D, Benedetti A, Paydar A, Martin I, Royce S, Pai M, Vernon A, Liendardt C, Burman W. Effect of duration and intermittency of rifampin on tuberculosis treatment outcomes: a systematic review and meta-analysis. PLoS Med 2009 Sep;6(9):e1000146. [Link]
28. †van Zyl Smit R, Zwerling A, Dheda K, Pai M. Within-subject variability of interferon-g assay results for tuberculosis and boosting effect of tuberculin skin testing: a systematic review. PLoS One 2009;4(12):e8517. [Link]
29. †Khan F, Minion J, Pai M, Royce S, Burman W, Harries AD, Menzies D. Treatment of active tuberculosis in HIV co-infected patients: a systematic review and meta-analysis. Clin Infect Dis 2010;50(9):1288-99. [Link]
30. Cattamanchi A, Davis JL, Pai M, Huang L, Hopewell PC, Steingart KR. Does Bleach Processing Increase the Accuracy of Sputum Smear Microscopy for Diagnosing Pulmonary Turberculosis? J of Clin Microbiology July 2010: 2433-2439. [Link]
31. Minion J, Pai M. Bacteriophage assays for rifampin resistance detection in Mycobacterium tuberculosis: updated meta-analysis. Int J Tuberc Lung Dis 2010: 14(8): 941-951. [Corresponding author][Link]
32. *Minion J, Leung E, Menzies D, Pai M. Microscopic-Observation Drug Susceptibility and Thin Layer Agar assays for the detection of drug resistant tuberculosis: a Systematic Review and Meta-Analysis. Lancet Infect Dis 2010;10(10):688-98 [Published online September 1, 2010 DOI:10.1016/S1473-3099(10)70165-1]. [Corresponding author]
33. Rylance J, Pai M, Lienhardt C, Garner P. Priorities for tuberculosis research: a systematic review. Lancet Infect Dis 2010;10:886-92.
34. *Zwerling A, van den Hoff S, Scholten J, Cobelens F, Menzies D, Pai M. Interferon-gamma release assays for tuberculosis screening of healthcare workers: a systematic review. Thorax (published ahead of print). [Corresponding author]
35. Cattamanchi A, Smith R, Steingart KR, Metcalfe JZ, Huang L, Hopewell, PC, Pai M. Interferon-gamma release assays for the diagnosis of latent tuberculosis infection in HIV-infected individuals - A systematic review and meta-analysis. JAIDS 2011 56(3):230-238. [Corresponding author]
36. Metcalfe JZ, Everett C, Steingart KR, Cattamanchi A, Huang L, Hopewell, PC, Pai M. Interferon-Gamma Release Assays for Active Pulmonary TB Diagnosis in Low- and Middle-Income Countries: Systematic Review and Meta-Analysis. J Infect Dis 2011 204: S1120‐S1129. [Corresponding author]
37. Minion J, Leung E, Talbot E, Dheda K, Pai M, Menzies D. Diagnosing tuberculosis with urine lipoarabinomannan: systematic review and meta-analysis. Eur Respir J 2011; 38:1398‐1405.
38. Steingart KR, Flores L, Dendukuri N, Schiller I, Laal S, Ramsay A, Hopewell PC, Pai M. Commercial serological tests for the diagnosis of active pulmonary and extrapulmonary tuberculosis: An updated systematic review and meta-analysis. PLoS Med 2011; 8(8): e1001062.
39. Leung E, Minion J, Benedetti A, Pai M, Menzies D. Microscopic Observation Drug-Susceptibility and Thin Layer Agar for Tuberculosis Diagnosis: A Systematic Review. Int J Tuberc Lung Dis (published ahead of print: http://dx.doi.org/10.5588/ijtld.10.0065).
40. Rangaka MX, Wilkinson KA, Glynn JR, Ling D, Menzies D, Mwansa‐Kambafwile J, Fielding K, Wilkinson RJ, Pai M. Predictive value of interferon‐gamma release assays for incident active tuberculosis: A systematic review and meta‐analysis. Lancet Infect Dis 2011 (published aheadof print (doi:10.1016/S1473‐3099(11)70210‐9) [Corresponding author]
41. Flores L, Steingart KR, Dendukuri N, Schiller I, Minion J, Pai M, Ramsay A, Henry M, Laal S. Antigen detection tests for the diagnosis of tuberculosis: A systematic review and metaanalysis. Clin Vaccine Immunol 2011;18:1616‐1627.
Narrative Reviews
1. Pai M. Unnecessary Medical Interventions: Caesarean sections as a case study. Economic & Political Weekly, July 29, 2000:2755-2761.
2. Miller I, Alagappan K, Pai M, van der Vlugt T, Doraisamy D, Rajagopalan A. Recognising emergency medicine in India. Natl Med J India 2001;14(5):325-328.
3. Pai M, Colford JM. Clinical trials in India sponsored by the pharmaceutical industry. Natl Med J India 2002;15(2):93-95.
4. Pai M, McCulloch M, Enanoria W, Colford JM. Systematic reviews of diagnostic test evaluations: what’s behind the scenes? ACP Journal Club 2004;141:A-11 – A-13. [Link]
5. Pai M, McCulloch M, Gorman JD, Pai N, Enanoria W, Kennedy G, Tharyan P, Colford, JM. Systematic reviews and meta-analyses: An illustrated, step-by-step guide. Natl Med J India 2004;17(2):86-95. [Link]
6. Pai M. Alternatives to the tuberculin skin test: Interferon-g assays in the diagnosis of Mycobacterium tuberculosis infection. Indian J Med Microbiol 2005;23(3)151-58. [Link]
7. **Nahid P, **Pai M, Hopewell PC. Advances in the diagnosis and treatment of tuberculosis. Proc Am Thorac Soc 2006;3:103-110. [**joint first author]. [Link]
8. Pai M, Kalantri SP, Dheda K. New tools and emerging technologies for the diagnosis of tuberculosis: Part I. Latent tuberculosis. Exp Rev Mol Diag 2006;6(3):413-422. [Link]
9. Pai M, Kalantri SP, Dheda K. New tools and emerging technologies for the diagnosis of tuberculosis: Part II. Active tuberculosis and drug resistance. Exp Rev Mol Diag 2006;6(3):423-32. [Link]
10. Pai M, Kalantri SP, Aggarwal AN, Menzies D, Blumberg HM. Nosocomial tuberculosis in India. Emerg Infect Dis 2006;12(9):1311-18. [Link]
11. Marais BJ, Pai M. Recent advances in the diagnosis of childhood tuberculosis. Arch Dis Child 2007; 92:446-452. [Link]
12. Pai M, Dheda K, Cunningham J, Scano F, O’Brien R. T Cell Assays for the Diagnosis of Latent Tuberculosis Infection: Moving the Research Agenda Forward. Lancet Infect Dis 2007;7:428-38. [Link]
13. Andersen P, Doherty TM, Pai M, Weldingh K. The prognosis of latent tuberculosis infection – can disease be predicted? Trends Mol Med 2007;13(5):175-182. [Link]
14. Marais BJ, Pai M. New approaches and emerging technologies in the diagnosis of childhood tuberculosis. Paed Resp Rev 2007;8:124-133. [Link]
15. Menzies D, Joshi R, Pai M. Risk of tuberculosis infection and disease associated with work in health care settings. Int J Tuberc Lung Dis 2007;11(6):593-605. [Link]
16. Pai M, Mohan A, Dheda K, Leung CC, Yew WW, Christopher DJ, Sharma SK. Lethal interaction: the colliding epidemics of tobacco and tuberculosis. Exp Rev Anti Infect Ther 2007;5(3):385-391. [Link]
17. Fair E, Hopewell PC, Pai M. The International Standards for Tuberculosis Care: Revisiting the cornerstones of tuberculosis care. Exp Rev Anti Infect Ther 2007;5(1):61-65. [Link]
18. Trajman A, Pai M, Dheda K, van Zyl Smit, Zwerling AA, Joshi R, Kalantri S, Daley P, Menzies D. Novel tests for diagnosing tuberculous pleural effusion: what works and what does not? Eur Resp Journal 2008;31(5):1098-1106. [Corresponding author]. [Link]
19. Migliori GB, Matteelli A, Cirillo D, Pai M. Diagnosis of multidrug resistant tuberculosis and extensively drug-resistant tuberculosis: current standards and challenges. Can J Infect Dis Med Micro 2008;19(2):169-172. [Corresponding author]. [Link]
20. Pai M, Ramsay A, O’Brien R. Evidence-based tuberculosis diagnosis. PLoS Med 2008;5(7): e156. [Link]
21. Pai M, O’Brien R. New Diagnostics for Latent and Active Tuberculosis: State of the Art and Future Prospects. Sem Resp Crit Care Med 2008;29(5):560-68. [Link]
22. Davies PDO, Pai M. The diagnosis and misdiagnosis of tuberculosis. Int J Tuberc Lung Dis 2008;12(11):1226-34.
23. Dheda K, van Zyl Smit R, Badri M, Pai M. T-cell interferon-g release assays for the rapid immunodiagnosis of tuberculosis: clinical utility in high-burden vs. low-burden settings. Curr Opinion Pulm Med 2009;15:188-200. [Link]
24. *Minion J, Zwerling A, Pai M. Diagnostics for tuberculosis: what new knowledge did we gain through The International Journal of Tuberculosis and Lung Disease in 2008? Int J Tuberc Lung Dis 2009;13(6):691-97. [Corresponding author][Link]
25. *Sohn H, Minion J, Albert H, Dheda K, Pai M. Tuberculosis diagnostic tests: how do we figure out their costs? Exp Rev Anti-Infect Ther 2009;7(6):723-733. [Corresponding author][Link]
26. Parkash O, Singh BP, Pai M. Regions of Differences Encoded Antigens as Targets for Immunodiagnosis of Tuberculosis in Humans. Scand J Immunol 2009; 70, 345–357.
27. Pai M, Minion J, Sohn H, Zwerling A, Perkins MD. Novel and Improved Technologies for Tuberculosis Diagnosis: Progress and Challenges. Clinics Chest Med 2009;30:701-16. [Link]
28. †van Zyl Smit R, Pai M, Yew WW, Leung CC, Zumla A, Bateman ED, Dheda K. Global Lung Health: The Colliding Epidemics of Tuberculosis, Tobacco Smoking, HIV and COPD. Eur Resp Journal 2010;35:27-33. [Link]
29. Pai M, Minion J, Steingart K, Ramsay A. New and Improved Tuberculosis Diagnostics: Evidence, Policy, Practice and Impact. Curr Op Pulm Med 2010;16:271-84. [Link]
30. **Wallis R, **Pai M, Menzies D, Doherty T, Walzl G, Perkins MD, Zumla A. Biomarkers and diagnostics for tuberculosis: progress, needs, and translation into practice. Lancet 2010: 375: 1920-37. [**joint first authors] [Link]
31. Van-zyl Smit R, Brunet L, Pai M, Yew WW. The convergence of the global smoking, COPD, Tuberculosis, HIV, and respiratory infection epidemics. Infect Dis Clinics North America 2010;24(3) 693-703.
32. *Ling DI, Zwerling A, Steingart KR, Pai M. Immune-based diagnostics for TB in children: what is the evidence? Paediatr Respir Rev 2011;12(1):9-15. [Corresponding author]
33. Smith R, Cattamanchi A, Steingart KR, Dheda K, Denkinger C, Winthrop K, Pai M. 'Interferon-gamma release assays for diagnosis of latent tuberculosis infection: evidence in immune-mediated inflammatory disorders. Curr Op Rheum 2011 2011 Jul;23(4):377‐384.
34. Denkinger C, Dheda K, Pai M. Guidelines on IGRAs for tuberculosis infection: concordance, discordance or confusion? Clin Microbiol Infect 2011;17:806‐814.
35. *Pinto L, Grenier J, Schumacher S, Denkinger C, Steingart KR, Pai M. Immunodiagnosis of tuberculosis: state-of-the-art. Med Prin Pract 2012;21:4‐13.
36. *Bhargava A, Pinto LM, Pai M. Mismanagement of tuberculosis in India: causes, consequences, and the way forward. Hypothesis 2011;9(1):e7.
37. Ramsay A, Steingart K, Cunningham J, Pai M. Translating tuberculosis research into global policies: the example of an international collaboration on diagnostics. Int J Tuberc Lung Dis 2011; 15(10):1283–1293.
38. Lienhardt C, Espinal M, Pai M, Maher D, Raviglione M. What research is needed to stop TB? Introducing the TB Research Movement. PLoS Med 2011;8(11): e1001135.
Others
Menzies D, Benedetti A, Paydar A, Royce S, Pai M, Burman W, Vernon A, Liendardt C. Standardized Treatment of active tuberculosis in previously treated patients, and/or with mono-resistance to isoniazid: a systematic review and meta-analysis. PLoS Med 2009;6(9) : e1000150. [Link]
Parkash O, Singh BP, Pai M. Regions of differences (RDs) encoded antigens as targets for immunodiagnosis of tuberculosis in humans. Scand J Immunology 2009 Oct;70(4):345-57. [Link]
Rylance J, Pai M, Lienhardt C, Garner P. Tuberculosis research priorities: a systematic review. Lancet Infect Dis (in press).
*Steingart KR, Henry M, Laal S, Hopewell PC, Ramsay A, Menzies D, Cunningham C, Weldingh K, Pai M. A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Postgrad Med J 2007 Nov;83(985):705-12. [Corresponding author]. [Link]
*Ling DI, Zwerling A, Pai M. Rapid diagnosis of drug-resistant tuberculosis using line probe assays: from evidence to policy. Exp Rev Resp Med 2008;2(5):583-588. [Corresponding author]. [Link]

