CLAIRE INFANTE-RIVARD

Professor (James McGill Professor)

McGill University

Department of Epidemiology, Biostatistics and

Occupational Health

Faculty of Medicine

1130 Pine Avenue West

Montréal, Quebec, Canada

H3A 1A3

claire.infante-rivard@mcgill.ca



My research interests are in: environmental and genetic epidemiology. I conduct research projects on childhood cancer and asthma, and on adverse pregnancy outcomes. I also have projects in the area of occupational epidemiology (maternal exposures at work, exposure assessment for epidemiology, occuaptional asthma and silicosis).

 

Students with an interest in my areas of research should contact me for more information on ongoing funded projects and possibilities for financial support. 
 



Some recent publications (a partial list for 1999-2010)
:

 

Infante-Rivard C, Gautrin D, Malo JL, Suissa S. Maternal smoking and incidence of childhood asthma. Am J Epidemiol 1999;150:528-31.

 

Infante-Rivard C, Labuda D, Krajinovic M, Sinnett D. Risk of childhood leukemia associated with exposure to pesticides and with gene polymorphisms. Epidemiology 1999;10:481-7. (Accompanied by an editorial; translated in German and published in: Umwelt Medizin Gesellschaft-Environment-Medicine -Society 2000;13:151-9)

 

Amre DK, Infante-Rivard C, Dufresne A, Ernst P, Durgawalw P. A case-control study of lung cancer amongst sugar cane farmers in India. Occup Environ Med 1999;56:548-52.

 

Lemyre E, Infante-Rivard C, Dallaire. The prevalence of congenital anomalies at birth in women at genetic risk but with a normal second trimester ultrasound. Teratology 1999;60:240-4.

 

Gautrin D, Leroyer C, Infante-Rivard C, Ghezzo H, Dufour JG, Girard D, Malo JL. Longitudinal assessment of airway caliber and responsiveness in workers at risk of chlorine exposure. Am J Resp Crit Care Med 1999;160:1232-7.

 

Gautrin D, Lapierre JG, Malo JL, Infante-Rivard C. Airway hyperresponsiveness and symptoms of asthma in a 6-year follow-up study of childhood asthma. Chest 1999;116:1659-64.

 

Arrieta MJ, Infante-Rivard C. Mother's organic solvent exposure during pregnancy and congenital malformations. (letter) JAMA 1999;282:1033.

 

Infante-Rivard C, Sinnett D. Preconceptional paternal exposure to pesticides in the workplace and increased risk of childhood leukemia. (letter)  Lancet 1999;364:1819.

 

Infante-Rivard C, Mathonnet G, Sinnett D. Diagnostic irradiation and polymorphisms in DNA repair genes in childhood leukemia. Environ Health Perspect 2000;108:495-8. [Chosen for a summary article in Science Selections section of the journal]

 

Infante-Rivard C, Krajinovic M, Labuda D, Sinnett D. Parental smoking, CYP1A1 genetic polymorphims and  childhood leukemia. Cancer Causes & Control 2000:11:547-553.

 

Khairy P, Infante-Rivard C. Long-term outcome of fulminant myocarditis as compared with acute (nonfulminant) myocarditis (letter) New Engl J Med 2000;343:

 

Infante-Rivard C, Jacques L.  An empirical study of parental recall bias. Am J Epidemiol 2000;152:480-6.

 

Infante-Rivard C, Fortier I, Olson E. Markers of infection, breast-feeding and childhood acute lymphoblastic leukemia.  Br J Cancer 2000;83:1555-64.

 

Monsó E, Malo JL, Infante-Rivard C, Magnan M, L'Archevèque, Trudeau C, Gautrin D. Individual characteristics associated with quitting in apprentices exposed to high molecular weight agents Am J Resp Crit Care Med 2000;161:1508-12.

 

Gautrin D, Ghezzo H, Infante-Rivard C, Malo JL. Incidence and determinants of IgE-mediated sensitization in apprentices. A prospective study. Am J Resp Crit Care Med 2000;162:1222-8.

 

Infante-Rivard C, Olson E,  Jacques L, Ayotte P. Drinking water contaminants and childhood leukemia. Epidemiology 2001;12:13-9.

 

Infante-Rivard C, Amre D, Gautrin D, Malo JL. Family size, day care attendance and breast-feeding in relation with the incidence of childhood asthma Am J Epidemiol 2001;153:653-8.

 

Fouron JC, Gosselin J, Amiel-Tison C, Infante-Rivard C, Fouron C, Skoll A, Veilleux L. Correlation between prenatal velocity waveforms in the aortic isthmus and neurodevelopmental outcome between 2 and 4 years of age. Am J Obstet Gynecol 2001;184:630-6.

 

Infante-Rivard C. Commentary on “Prior induced abortion increased the risk of spontaneous abortion only when the interval to next pregnancy was short”. Evidence-based Obstet Gynecol 2001;3:24-25. Summary of: Zhou W, Olsen J, Nielsen GL, Sabroe S. Risk of spontaneous abortion following induced abortion is only increased with short interpregnancy interval. J Obstet Gynaecol 2000;20:49-54.

 

Gautrin D, Ghezzo H, Infante-Rivard C, Malo JL. Incidence and host determinants of probable occupational asthma in apprentices exposed to laboratory animals Am J Resp Crit Care Med 2001;163:899-904.

 

Stringer B. Infante-Rivard C, Hanley J. Quantifying and reducing the risk of bloodborne pathogen exposure Am Assoc Oper Room Nursing 2001;73:1135-46.   

 

Infante-Rivard C, Amre D. Congenital anomalies in the index child and in his family as a risk factors for childhood leukemia. Int J Epidemiol 2001;30:350-2.

 

Archambault S, Malo JL, Infante-Rivard C, Ghezzo G, Gautrin D. Incidence of sensitization, symptoms and diseases in apprentices starting exposure to latex J Clin Aller Immunol 2001;107:921-3.

 

Gautrin D, Ghezzo H, Infante-Rivard C, Malo JL. Natural history of sensitization, symptoms and diseases in apprentices exposed to laboratory animals Eur Respir J 2001;17:904-8.

 

Fouron JC, Proulx F, Gosselin, Infante-Rivard C. Investigation des arythmies foetales par enregistrement simultané des vélocités sanguines dans l’aorte ascendante et la veine cave supérieure. Arch Mal Coeur Vaisseaux 2001;94;1063-71.

 

Deadman J, Infante-Rivard C. Individual estimation of exposures to extremely low frequency magnetic fields in jobs commonly held by women.  Am J Epidemiol 2002;155:368-78.           

 

Gautrin G, Ghezzo H, Infante-Rivard C,  Malo JL. Host determinants for the development of llergy in apprentices exposed to laboratory animals.  Eur Resp J 2002;19:96-103.

 

Théorêt Y, Rivard GE, Infante-Rivard C, Yotov W. Assay of total plasma homocysteine in perinatology. Clin Chim Acta 2002;319:63-6.

 

Infante-Rivard C, Krajinovik M, Labuda D, Sinnett D. Childhood acute lymphoblastic leukemia associated with parental alcohol consumption and carcinogen-metabolizing genetic polymorphisms. Epidemiology 2002;13:277-81. [Appeared as an abstract in Alcohol Research, an international abstract journal].

 

Infante-Rivard C Sinnett D.  Amre D. GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water; effect on childhood leukemia Environ Health Perspect 2002;110:591-3.

 

Gosselin J, Amiel-Tisson C, Infante-Rivard C, Fouron C, Fouron JC. Minor neurological signs and developmental skills in high-risk children between 2 and 5 years of age. Dev Med Child Neurol 2002;44:323-8.

 

Marrett, LD, Frood J, Ugnat AM, and the Cancer in Young Adults in Canada (CYAC) Working Group. Cancer Incidence in Young Adults in Canada: Preliminary Results of a Cancer Surveillance Project. Chronic Diseases in Canada 2002;23:66-73.      

Infante-Rivard C, Rivard GE, Yotov W, Théorêt Y. Perinatal reference ranges for plasma homocysteine and factors influencing levels. Clin Chem 2002;48:1100-2.

 

Infante-Rivard C, Rivard GE, Yotov W. Génin E, Guiguet M, Weinberg C, Gauthier R, Feoli-Fonseca JC. An association study and a family-based study of thrombophilic polymorphisms in intrauterine growth retardation. New Engl J Med 2002;347:19-24. [With comments in an accompanying editorial]

 

Labuda D, Krajinovic M, Sabbagh A, Infante-Rivard C, Sinnett D. Parental genotypes in the risk of complex disease. Am J Hum Gen 2002;71:193-7.

 

Dufresne A, Infante-Rivard C. Mineralogy and morphology of fibres determined by Transmission Electron Microscopy (TEM) and Energy Dispersive Spectroscopy (EDS) in steam tunnels. Ann Occup Hyg 2002:46;(suppl 1):121-4.

 

Dufresne A, Anthes M, Santos B, Infante-Rivard C. Airborne asbestos fibres in steam tunnels. A qualitative analysis by PLM, and a quantitative analysis by PCOM and TEM/EDS. Ann Occup Hyg 2002:46;(suppl 1):125-7.

 

Wognin SB, Infante-Rivard C, Yekoue-Kouane BY, N’gbesso R, Ostiguy G, Bonny JS, Tuo N, Kouassi YM. Etude de la prévalence de la silicose chez les travailleurs d’une carrière de granit à Abidjan. Arch Mal Prof Méd Travail 2002;63:25-31.

 

Stringer B, Infante-Rivard C, Hanley J. The effectiveness of  the hands-free technique in reducing operating rooms injuries. Occup Environ Med 2002;59:703-7.

 

Amiel-Tisson C, Gosselin J, Infante-Rivard C. Head growth and cranial assessment as part of the neurological examination in infancy. Dev Med Child Neurol 2002;44:643-8.

 

Gautrin D, Ghezzo H, Infante-Rivard C, Malo JL. Incidence and determinants of work-related rhinoconjunctivitis in apprentices stating in pastry-making. Allergy 2002;57:913_8.

 

Dufresne A, Infante-Rivard C, Gautrin D, Malo JL. Exposure to formaldehyde in animal health care apprentices.  Am Ind Hyg Ass J 2002;63:647-50.

 

Amre D, Infante-Rivard C, Gautrin D, Malo JL. Socio-economic status and use of health services and medication in a cohort of asthmatic children.  J Asthma 2002;39:625-31.

 

Labuda D, Krajinovic M, Sabbagh A, Infante-Rivard C. Reply to letters on “Parental genotypes in the risk of complex disease”. (Letter) Am J Hum Gen 2002;71:1240-2.

 

Laverdière C, Gauvin F, Hébert PC, Infante-Rivard C, Hume H, Toledano BJ, Guertin MC, Lacroix J. Survey of transfusion practices in pediatric intensive care units. Ped Crit Care Med 2002;3:335-40.

 

Infante-Rivard, Rivard GE, Gauthier R. Thrombophilia polymorphisms and intrauterine growth restriction. (Letter) New Engl J Med 2002;347:1530-1.

 

Infante-Rivard C. Hospital or population controls for cases of severe childhood diseases?  Am J Epidemiol 2003;157:176-182.

 

Ruskamp JM, Fouron JC, Gosselin, J Raboisson MJ, Infante-Rivard C,, Proulx F. Reference values for an index of fetal aortic isthmus blood flow during the second half of pregnancy. Ultrasound Obstet Gynecol 2003:21:441-4.

 

Infante-Rivard C. Diagnostic x rays, DNA repair genes and childhood acute lymphoblastic leukemia.  Health Physics 2003;85:60-4.

 

Infante-Rivard C, Deadman JE. Maternal occupational exposure to extremely low frequency magnetic fields during pregnancy and childhood leukemia.  Epidemiology 2003;14:437-41.

 

Infante-Rivard C, Lévy E, Rivard GE, Guiguet M, Feoli-Fonseca JC. Small babies receive the cardiovascular protective apolipoprotein ,2 allele less frequently than expected. J Med Gen 2003;40:626-9.

 

Infante-Rivard C, Rivard GE, Gauthier R, Théorêt Y. An unexpected relation between maternal and newborn plasma homocysteine and intrauterine growth restriction? Clin Chem 2003;49:1476-82. (Accompanied by an editorial; Cattaneo M, 49:1432-3).

 

El-Zein M, Malo JL, Infante-Rivard C, Gautrin D. Prevalence and association of welding-related systemic and respiratory symptoms in welders. Occup Environ Med 2003;60:655-61.

 

El-Zein M, Malo JL, Infante-Rivard C, Gautrin D. Incidence of probable occupational asthma and changes in airway caliber and responsiveness in apprentice welders. Eur Resp J 2003;22:513-8.

 

Salino D, Infante-Rivard C. Le niveau de connaissance des travailleurs chargés de l'application de pesticides en Nouvelle Calédonie : le regard du médecin du travail. Arch Mal Prof  Méd Travail 2003;64;253-265.

 

Bard H,  Côté A, Praud JP, Infante-Rivard C, Gagnon C. HbF synthesis determined by g-mRNA/g-mRNA+ b-mRNA quantitation in infants being monitored at home following an apparent life-threatening event.  Pediatrics 2003;112:e285-e288.

 

 Infante-Rivard C. Guiguet M. Family history of hematopoietic and other cancers in children with acute lymphoblastic leukemia. Cancer Detection Prev 2004;28:83-7.

 

Infante-Rivard C, Rivard GE. Unexpected relationship between  plasma homocysteine and intrauterine growth restriction: response. Clin Chem 2004;50:784-5.

 

Infante-Rivard C. Drinking water contaminants, genetic polymorphisms and fetal growth.  Environ Health Perspect 2004;112:1213-6.

 

 SEQ CHAPTER \h \r 1Shaw AK  Infante-Rivard C, Morrison HI. Use of medication during pregnancy and risk of childhood acute lymphocytic leukemia Cancer Causes & Control; 2004;15:931-7.

 

Attia J, Dudding T, Infante-Rivard C. Addendum to: The association between adverse pregnancy outcomes and maternal factor V Leiden genotype. A meta-analysis. (Letter) Throm Haem 2004;92:434.

 

Infante-Rivard C, Rivard GE, Guiguet, Gauthier R. Thrombophilic polymorphisms and intrauterine growth restriction. Epidemiology 2005;16:281-7.

 

 Infante-Rivard C.  Severity of silicosis at compensation between medically screened and unscreened workers. J Occup Environ Med 2005;47:265-71.

 

Infante-Rivard C, Siemiatycki J, Lakhani R, Nadon L. Maternal exposure to occupational solvents and childhood leukemia. Environ Health Perspect 2005;113:787-92.

 

El-Zein M, Infante-Rivard C, Dufresne A, Malo JL, Gautrin D. Is metal fume fever a determinant of welding-related respiratory symptoms and/or bronchial hyperresponsiveness? A longitudinal study  Occup Environ Med 2005;62:688-94.

 

Infante-Rivard C, Weinberg CR. Parent-of-origin transmission of thrombophilic alleles to intrauterine growth restricted newborns and transmission-ratio distortion in unaffected newborns. Am J Epidemiol 2005;162:891-7.

 

Infante-Rivard C, Weinberg CR, Guiguet M. Xenobiotic-metabolizing genes and small-for-gestational births. Interaction with maternal smoking. Epidemiology 2006;17:38-46.

 

Kistner EO, Infante-Rivard C, Weinberg CR.A method for using incomplete triads to test maternally-mediated genetic effects and parent-of-origin effects in relation to a quantitative trait. Am J Epidemiol 2006;163:255-61.

 

Infante-Rivard C, El-Zein M. Parental alcohol consumption and childhood cancers: a review. Journal of Toxicol Environ Health: Part B 2006;10:101-129.

 

Infante-Rivard C, Weichenthal S. Pesticide exposures and childhood cancers: An Update of Zahm and Ward’s 1998 Review. Journal of Toxicol Environ Health: Part B 2006;10:81-99

 

Shaw AK, Li P, Infante-Rivard C. Early infection and risk of childhood brain tumours. Cancer Causes & Control 2006;17:1267-74.

 

Weichenthal S, Dufresne A, Infante-Rivard C.  Indoor Ultrafine Particles and Childhood Asthma: a review of the evidence. Indoor Air 2007;17:81-91.

 

Assouline S, Meyer R, Infante-Rivard C, Connors JM, Belch A, Crump M, Kouroukis T, Eisenhauer E.  Development of adapted RECIST Criteria to assess response in lymphoma and their comparison to the International Workshop Criteria. Leukemia and Lymphoma 2007;48:513-20.

 

Weichenthal S, Dufresne A, Infante-Rivard C, Joseph L. Indoor Ultrafine Particles and Home Heating Systems: A Cross-Sectional Survey of Canadian Homes During the Winter Months  J Exp Sci Environ Epid 2007; 17:288-97.

 

Infante-Rivard C, Vermunt JK, Weinberg CR. Excess transmission of the NQO1 C609T polymorphism in families of children developing acute lymphoblastic leukemia. Am J Epidemiol 2007;165:1248-54.

 

Infante-Rivard C. Caffeine intake and intrauterine growth restriction: modifying effects of xenobiotic-metabolizing genes and smoking Paed. Perinatol Epidemiol 2007;21:300-9.

 

Infante-Rivard C. Studying genetic predisposition among small-for-gestational-age newborns. (Invited paper). Sem Perinatol 2007;31:213-8.

 

Weksberg R, Shuman C, Wilkins-Haug L, Mann M, Croughan M, Stewart D,  Rakowsky C,  Leader A,  Hall J,  Friedman JM,  Leigh Simpson J, Holmes L, Infante-Rivard C. Workshop report: evaluation of genetic and epigenetic risks associated with assisted reproductive technologies and infertility. Fertil Steril 2007;88:27-31.

 

Weichenthal S, Dufresne A, Infante-Rivard C. Indoor nitrogen dioxide and VOC exposures: Summary of evidence for an association with childhood asthma and a case for the inclusion of indoor ultrafine particle measures in future studies. Indoor and Built Environment 2007;16:387-99.

 

Weichenthal S, Dufresne A, Infante-Rivard C, Joseph L. Characterizing and predicting  ultrafine particle counts in Canadian classrooms during the winter months: model development and evaluation. Environ Research 2008;106:349-60.

 

Gautrin D. Ghezzo H. Infante-Rivard C. Magnan M. L'archeveque J. Suarthana E. Malo JL. Long-term outcomes in a prospective cohort of apprentices exposed to high-molecular-weight agents.  Am J Resp Crit Care Med 2008;177:871-9.

 

Weichenthal S, Dufresne A, Infante-Rivard C. Joseph L. Determinants of ultrafine particle

exposures in transportation environments: Findings of an 8-month survey conducted in Montréal, Canada. J Exp Sci Environ Epid 2008;18:551-63.

 

O’Brien SF, Fan W, Xi G, Yi Q-L, Goldman M, Fearon MA, Infante-Rivard C, Chiavetta JO, Willems B, Pi D, Fast M, Delage G. Declining hepatitis C rates in first time blood donors: insight from surveillance and case-control risk factor studies. Transfusion 2008;48:902-9.

 

 Infante-Rivard C. Chemical  risk factors and childhood leukemia: a review of recent studies. Rad Protection Dosimetry 2008;132:220-7.

Little J, Higgins J, Ioannidis JPA, Moher D, Gagnon F, von Elm E, Khoury MJ, Cohen B,  Davey-Smith G,  Grimshaw J, Scheet P, Gwinn M, Williamson RE, Zou GY, Hutchings K, Johnson CY, Tait V, Wiens M,  Golding J, van Duijn C, McLaughlin J, Paterson A, Vogan KJ, Wells G,  Fortier I, Freedman M, Zecevic M, King R, Infante-Rivard C, Stewart A, Birkett N. STROBE Extension to Genetic Association studies: STREGA (STrengthening the REporting of Genetic Association studies). Annals of Intern Med  2009;150:206-15.) and also published in Eur J Clin Invest 2009;39(4) 247-66.  Eur J Epidemiol 2009;24:37-55; Hum Genet 2009;125:131-51, Plos Med 2009;6(2):e22, Feb 3; J Clin Epidemiol, 2009; 62(6):597-608; Genet Epidemiol 2009;33(7):581-98.

 

Attia J, Ioannidis J, Thakkinstian A, McEvoy M, Scott R, Minelli C, Thompson J, Infante-Rivard C, Guyatt G. Users’ guides to the medical literature. XXVI.  How to use an article about genetic association. A. Background concepts. JAMA 2009;301:74-81.

 

Attia J, Ioannidis J, Thakkinstian A, McEvoy M, Scott R, Minelli C, Thompson J, Infante-Rivard C, Guyatt G Users’ guides to the medical literature. XXVI. How to use an article about genetic association. B.  Are the results of the study valid? JAMA 2009;301:191-7.

 

Attia J, Ioannidis J, Thakkinstian A, McEvoy M, Scott R, Minelli C, Thompson J, Infante-Rivard C, Guyatt G. Users’ guides to the medical literature. XXVI. How to use an article about genetic association. C. What are the results and will they help me in caring for my patients? JAMA  2009;301:304-8.

 

Paterson AD, Waggott D, Schillert A, Infante-Rivard C, Bull SB, Yoo YJ, Pinnaduwage D. Transmission ratio distortion in the Framingham Heart Study. BMC Proceedings  Genetic Analysis Workshop 16. 2009;3(Suppl 7):S51.

 

Li P, McLaughlin J, Infante-Rivard C. M. Maternal occupational exposure to extremely low frequency magnetic fields and risk of brain tumors in offspring. Cancer Causes & Control 2009;20(6):945-55.

 

Infante-Rivard C. From rags to genes: Mixing research paradigms (Invited Editorial) Chron Dis Canada. 2009:29:48.

 

Infante-Rivard C, Mirea L, Bull SB. Combining case-control and case-trio data from the same population in genetic association analyses: overview of approaches and illustration with a candidate gene study. Am J Epidemiol 2009;170:657-64.

 

Rudant J, Clavel J, Infante-Rivard C. Selection bias in studies of household exposure to pesticides and childhood acute leukemia. (advance online publication, December 16, 2009; J Exp Sci Environ Epidemiol doi:10.1038/jes.2009.61)

 

Des Roches A, Infante-Rivard C, Paradis L, Paradis J, Haddad E. Peanut Allergy:  is Maternal Transmission of Antigens during pregnancy and breastfeeding a Risk Factor? (In press in J Investig Allergol Clin Immunol 2010;20 (4):July-August)

 

Luu TM, Lefebvre F, Riley P, Tessier R, Infante-Rivard C. Continuing utilization of community health services in extremely premature infants. (In press in Arch Dis Child). 

 

Infante-Rivard CGenetic association between paraoxonase 1 gene (PON1) single nucleotide polymorphisms and small-for-gestational age outcome in related and unrelated subjects. (Advance publication April 7, 2010 Am J Epidemiol 2010; doi: 10.1093/aje/kwq031)