Session 2: Outline Review of KKMN Sections 5-4 to 5-8 ================================== 5.4 Assumptions - see my notes 5.5 Estimates of slope/intercept 5.6 Residual variation - MSE = average squared "error" - Root Mean Squared Error = MSE = square root of average squared error = "average" error (roughly!) = "average" residual 5.7 Inferences re slope/intercept - 2 ingredients - standard error of parameter estimate - t-deviate (with n-2 degrees of freedom) - why n-2 df? See my notes on 5.6 "why do we divide by n-2?" - Factors affecting the standard errors - see "Factors affecting reliability of slope/intercept estimates" in "Inferences re S. L. R." in my notes on M&M ch 2/9 5.8.1 Inferences re: slope - cf diagrams on page 56 of KKMN New: KKMN Sections 5.9 & 5.10 ============================= 5.9 The REGRESSION LINE as object - Meaning of "true" line - a line of mu(Y|X)'s!! - estimate of line - "centered" version - Estimate of mu(Y|value X0 of X) - X0 not necessarily in dataset - Ingredients - SE of mu_hat (Y|X0) formula 5.12 p. 57 - t deviate - note: SE larger the further X0 is from Xbar. - Why? - (Not mentioned in KKMN) CI's are for mu(Y) at a specific X0 value not for entire line (see Neter). 5.9 "Prediction" of a new Y value at X=X0 - best (point) estimate is estimate of mu(Y|X0) - BUT... Y is an INDIVIDUAL value! it is not influenced by n used to estimate mu(Y|X0) Y will vary around true mu(Y|X0) according to the SD of INDIVIDUAL Y's at X=X0 - SO... Uncertainty concerning Y is amalgam of - SD of INDIVIDUALS - uncertainty in estimate of mu(Y|X0) and is (llmost) independent of n used to estimate mu(Y|X0) ==> "Prediction Bands" NB Difference between 5.8 and 5.9 --------------------------------- CI's for AVERAGE value Prediction bands for INDIVIDUAL value. Examples: Alcohol and Eye Movement Noninvasive prediction (see Appropriate use of prediction bands letter to NEJM ... on web page under chapter 5) * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * Chapter 6 of KKMN ================= Highlights only - r <==> b (slope) - r is range-dependent - Method Comparisons DONT use r (see article on Method Agreement by Bland and Altman * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * - Further Steps in computing - Getting existing data into SAS