/* Dear Dr. Hanley, Thank you for your very nice note. I have attached a spreadsheet with the numerators and denominators from the JAMA article on folic acid fortification. I am very pleased that you plan to use this as an example for your course in the fall. Please let me know if there is anything in the spreadsheet that requires further explanation or clarification. Sincerely, Margaret Honein National Center on Birth Defects and Developmental Disabilities, CDC */ /* Data below were extracted by JH from this spreadsheet */ DATA sasuser.fa_bd; INPUT latecare /* 1 if 3rd trimester only or no prenatal care */ /* 0 if 1st or 2nd trimester care */ /* . if information not available */ birth_q birth_yr /* quarter and year of birth */ sb_no /* number of cases of spina bifida */ ane_no /* number of cases of anencephaly */ n_births /* number of live births */ /* Data from US birth certificates, */ /* National Center for Vital Statistics, CDC */ /* EXCLUDES RESIDENTS OF CT, MD, NM, NY, AND OK */ ; birth_tq = (birth_yr - 1900) + birth_q/4 - 0.125 ; /* quarter */ sb_rate = round( 100000 * (sb_no / n_births), 0.01); /* S.B. rate per 100 000 */ ane_rate = round( 100000 * (ane_no / n_births), 0.01); /* Anenc. rate per 100 000 */ LINES; 0 1 1990 214 125 809240 0 2 1990 205 144 845066 0 3 1990 210 146 898490 0 4 1990 194 122 834075 0 1 1991 191 149 804491 0 2 1991 196 161 834652 0 3 1991 198 124 890893 0 4 1991 203 120 829252 0 1 1992 154 90 808228 0 2 1992 167 85 835465 0 3 1992 179 106 871513 0 4 1992 201 94 827985 0 1 1993 188 101 797896 0 2 1993 199 104 823959 0 3 1993 209 121 871643 0 4 1993 195 78 812994 0 1 1994 207 66 794678 0 2 1994 206 92 810193 0 3 1994 201 81 862399 0 4 1994 193 87 811083 0 1 1995 201 85 778848 0 2 1995 224 95 808426 0 3 1995 237 86 858145 0 4 1995 214 80 795491 0 1 1996 181 101 779254 0 2 1996 228 81 796192 0 3 1996 210 92 859359 0 4 1996 210 94 807993 0 1 1997 218 95 774582 0 2 1997 198 88 807490 0 3 1997 208 83 855239 0 4 1997 173 105 807249 0 1 1998 186 56 788877 0 2 1998 184 92 815322 0 3 1998 191 82 848694 0 4 1998 154 68 818966 0 1 1999 175 81 790898 0 2 1999 169 79 815801 0 3 1999 146 78 880576 0 4 1999 169 86 819735 1 1 1990 14 21 54613 1 2 1990 17 16 52394 1 3 1990 22 16 53786 1 4 1990 11 10 52389 1 1 1991 11 23 51523 1 2 1991 11 12 49668 1 3 1991 17 14 50741 1 4 1991 19 12 49532 1 1 1992 16 13 47676 1 2 1992 16 12 43990 1 3 1992 14 7 43751 1 4 1992 23 9 42954 1 1 1993 17 8 42218 1 2 1993 16 11 40494 1 3 1993 15 12 41789 1 4 1993 11 12 38921 1 1 1994 16 11 38255 1 2 1994 8 5 35687 1 3 1994 17 8 36323 1 4 1994 11 2 35888 1 1 1995 11 5 35860 1 2 1995 13 15 34051 1 3 1995 13 11 36222 1 4 1995 10 5 35324 1 1 1996 11 5 34193 1 2 1996 8 11 31817 1 3 1996 16 10 32795 1 4 1996 11 2 32589 1 1 1997 11 14 32969 1 2 1997 9 7 32140 1 3 1997 9 8 32363 1 4 1997 14 9 32773 1 1 1998 15 4 33863 1 2 1998 9 7 31749 1 3 1998 12 7 33034 1 4 1998 7 7 32081 1 1 1999 6 13 32656 1 2 1999 8 2 30571 1 3 1999 8 7 32078 1 4 1999 9 7 31936 . 1 1990 5 7 13091 . 2 1990 4 5 13341 . 3 1990 4 4 15116 . 4 1990 7 4 13616 . 1 1991 3 1 12632 . 2 1991 3 5 13402 . 3 1991 7 4 14322 . 4 1991 10 6 13821 . 1 1992 5 12 13355 . 2 1992 5 7 13872 . 3 1992 5 5 14119 . 4 1992 4 3 13352 . 1 1993 5 6 12508 . 2 1993 4 4 12881 . 3 1993 8 2 13457 . 4 1993 6 1 13305 . 1 1994 5 3 13522 . 2 1994 3 7 13171 . 3 1994 5 5 14740 . 4 1994 6 4 15516 . 1 1995 9 3 13483 . 2 1995 5 3 14159 . 3 1995 11 4 15140 . 4 1995 6 4 13749 . 1 1996 3 3 15177 . 2 1996 4 5 15469 . 3 1996 6 2 16869 . 4 1996 5 2 16401 . 1 1997 4 3 14931 . 2 1997 3 6 14617 . 3 1997 1 4 15256 . 4 1997 3 2 15583 . 1 1998 4 1 16205 . 2 1998 9 4 16194 . 3 1998 5 3 37263 . 4 1998 4 6 18527 . 1 1999 9 3 18675 . 2 1999 7 2 19105 . 3 1999 5 7 20421 . 4 1999 8 7 19875 ; run;