Research Centre

Below you will find information about Research Activities in the Cardiology Division. The information is in three sections:

Submit your study information here- include contacts, purpose and other info to help you recruit and publicize your work.

Research Submission Form

Due to unauthorised posting of links to pornographic and other malware sites, this form has been removed. I am sorry if the links offended anyone. They certainly did not represent McGill or myself.

R. Haichin, webmaster

There are active basic labs in lipid research (Drs. Genest, Marcil, Sniderman, Cianflone), genetics (Dr. Engert) as well as clinical research projects at the various sites. There is a Technology Assessment Unit at RVH headed by Dr. J. Brophy and Epidemiologic Research at all adult sites (Drs. Brophy, Eisenberg, S. Grover, L. Pilote [MGH Clinical Epidemiology]. Dr. Buithieu has active studies in brachial artery reactivity and other vascular biology. Dr. Giannetti has active research interests in Heart Failure, Transplantation and Ventricular Assist Devices.

Clinical Trials

Study Name:	BEAUTIFUL
Goals:	To show safety and utility of a new If channel blocker ivradabine in patients with CAD and decreased LV EF.
Principal Investigator:	RVH Site: Dr. Richard Haichin
Contact Person:	RVH Site: Violeta Toyota
Inclusion/Exclusion:	Stable CAD, EF <40%, heart rate >60/min at rest, LVEDD 56 mm on echo. Long term placebo controlled study.
Sponsorship:	Servier

Study Name:	HAT Study
Goals:	Post anterior MI with EF>30%- randomisation to teaching video resuscitation vs home AED
Principal Investigator:	Dr. M. Sami.
Contact Person:	Diane Leibling or Dr. M. Sami.
Inclusion/Exclusion:
Sponsorship:	NIH

Study Name:	Genetics of High Density Lipoproteins
Goals:	Positional cloning, candidate gene and gene chip strategy for novel genes
Principal Investigator:	J. Genest MD; M. Marcil, PhD
Contact Person:	as above
Inclusion/Exclusion:	HDL-c <5th percentile for age and gender
Sponsorship:	CIHR grants, Heart and Stroke Foundation

Study Name:	TIMI 36- MERLIN
Goals:	To assess effects of ranolazine on ischemic events in ACS
Principal Investigator:	R. Haichin (RVH), T. Huynh (MGH)
Contact Person:	V. Toyota (RVH), Research nurses Cardiology (MGH)
Inclusion/Exclusion:	ACS within 48 hours. Exclusion for intolerance to meds.
Sponsorship:	CVT Therapeutics

Study Name:	JUPITER
Goals:	To assess whether rosuvastatin 20 mg or placebo will prevent cardiovascular events in patients with low LDL and high hs-CRP
Principal Investigator:	RVH: J. Genest, Sub I: M. Smilovitch, J. Buithieu
Contact Person:	Colette Rondeau, Andrea Serpa
Inclusion/Exclusion:	15, 000 patients with LDL < 3.36 and hs CRP > 2.0. Age M>55, F>60 with established. TG < 5.65. Follow-up 3,5 years
Sponsorship:	Astra Zeneca

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Staff and Contacts

Violeta Toyota- Research Nurse, Clinical Cardiology, Tel. Local 34983 RVH E Mail violeta.toyota@muhc.mcgill.ca

Andrea Serpa- Research Nurse, Clinical Cardiology, Tel. Local 35661 RVH E Mail andrea.serpa@muhc.mcgill.ca

Diane Leibling, Research Nurse, Clinical Cardiology. Tel. Local-

Other links below will guide you to several related McGill sites and external sites.

McGill University Medicine Research Site

Canadian Institutes of Health Research

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