Camille Lehuede


RESEARCH PROJECT

Studying the metabolic crosstalk between hepatocytes and breast tumor cells during liver metastasis.

BACKGROUND

I recently joined Dr Siegel’s lab in 2015 as a postdoctoral fellow after completing my PhD and I was looking at the role of adipocytes in breast cancer progression and chemoresistance under the supervision of Pr. Catherine Muller (IPBS, Toulouse, France). Before my arrival, the lab has recently shown that metastatic breast cancer cells displayed both elevated glycolysis and OX-PHOS compared to non-metastatic tumor cells. Moreover, liver-metastatic cells prioritize glycolysis and a reduced mitochondrial metabolism compared to bone or lung metastatic breast cancer cells. I am currently deciphering the role of the metabolic cooperation between hepatocytes and liver-metastatic breast tumor cells in promoting the growth of metastatic cells.

Publications

CONTACT INFO

Rosalind and Morris Goodman Cancer Research Centre - McGill University
1160 Pine Ave. West (Room 508)
Montreal, Quebec (Canada)
H3A 1A3
T. 514.398.8889
F. 514.398.6769
Email