PUBLICATIONS (in chronological order):

1. Pelletier, J. and N. Sonenberg. (1985). Insertion Mutagenesis to Increase Secondary  Structure Within the 5' Noncoding Region of a Eukaryotic mRNA Reduces Translational Efficiency. Cell  40: 515-526.

2. Darveau, A., J. Pelletier, and N. Sonenberg. (1985). Differential Efficiences of In Vitro Translation of Mouse c-myc Transcripts Differing in the 5' Untranslated Region. Proc. Natl. Acad. Sci. USA  82: 2315-2319.

3. Sarkar, G., J. Pelletier, R. Bassel-Duby, A. Jayasuriya, B.N. Fields, and N. Sonenberg. (1985). Identification of a new Polypeptide Coded by Reovirus Gene S1. J. Virol. 54: 720-725.

4. Pelletier, J. and N. Sonenberg. (1985). Photochemical Crosslinking of Cap Binding  Proteins to Eukaryotic mRNAs: Effect of mRNA 5' Secondary Structure. Mol. Cell. Biol. 5: 3222-3230.

5. Pelletier, J., R. Nicholson, R. Bassel-Duby, B.N. Fields, and N. Sonenberg. (1987). Expression of Reovirus Type 3 (Dearing Strain) sigma 1 and sigma s Polypeptides in Escherichia coli. J. Gen. Virol. 68: 135-145.

6. Pelletier, J. G. Kaplan, V.R. Racaniello, and N. Sonenberg. (1988). Cap-Independent  Translation of Poliovirus mRNA is Conferred by Sequence Elements Within the 5' Noncoding Region. Mol. Cell. Biol. 8: 1103-1112.

7. Milburn, S.C., J. Pelletier, N. Sonenberg, and J.W.B. Hershey. (1988). Identification of the 80-kDa Protein that Crosslinks to the Cap Structure of Eukaryotic mRNAs as Initiation Factor eIF-4B. Arch. Biochem. 264: 348-350.

8. Pelletier, J., G. Kaplan, V.R. Racaniello, and N. Sonenberg. (1988). Translational Efficiency of Poliovirus mRNA:  Mapping Inhibitory cis-Acting Elements within the 5' Noncoding Region. J. Virol. 62: 2219-2227.

9. Trono, D., J. Pelletier, N. Sonenberg, and D. Baltimore. (1988). Translation in Mammalian Cells of a Gene Linked to the Poliovirus 5' Noncoding Region. Science 241: 445-448.

10. Pelletier, J. and N. Sonenberg. (1988). Internal Initiation of Translation of Eukaryotic mRNA Directed by a Sequence Derived from Poliovirus RNA. Nature  334: 320-325.

11. Pelletier, J. , M.E. Flynn, G. Kaplan, V.R. Racaniello, and N. Sonenberg. (1988) Mutational Analysis of the Upstream AUG Codons of Poliovirus RNA. J. Virol. 62: 4486-4492.

12. Pelletier, J. and N. Sonenberg. (1988).  Internal Binding of Eukaryotic Ribosomes on Poliovirus RNA: Translation in HeLa Extracts. J. Virol. 63: 441-444.

13. Boylan, M.O., J. Pelletier, S. Dhepagnon, S. Trudel, N. Sonenberg, and E.A. Meighen. (1989). Construction of a Fused Lux AB Gene by Site-directed Mutagenesis. J. Biolum. Chemilum. 4: 310-316..

14. Boylan, M.O., J. Pelletier, and E.A. Meighen. (1989). Fused Bacterial Luciferase  Subunits Catalyze Light  Emission in Eukaryotes and Prokaryotes. J. Biol. Chem. 264: 1915-1918.

15. Altmann, M., P.P. Muller, J. Pelletier, N. Sonenberg, and H. Trachsel. (1989). A Mammalian Translation Initiator Factor can Substitute for its Yeast Homologue In Vivo. J. Biol. Chem. 264: 12145-12147.

16. Meerovitch, K., J. Pelletier, and N. Sonenberg. (1989). A Cellular Protein that Binds to the 5' Noncoding Region of Poliovirus RNA:Implications for Translation Initiation. Genes & Devel. 3: 1026-1034.

17. Rozen, F., J. Pelletier, H. Trachsel, and N. Sonenberg. (1989). A Lysine Substitute  in the ATP Binding Site of Eukaryotic Initiation Factor-4A Abrogates Nucleotide Binding Activity. Mol. Cell. Biol. 9: 4061-4063.

18. Davies, M.V., J. Pelletier, K. Meerovitch, N. Sonenberg, and R.J. Kaufman. (1991). Expression of Poliovirus Proteinase 2Apro  Expression on Cellular Metabolism. J. Biol. Chem. 266: 14714-14720.

19. Altmann, M., Blum, S., Pelletier, J., Sonenberg, N., Wilson, T.M.A., and Trachsel, H. (1990). Translation initiation factor-dependent extracts from Saccharomyces cerevisiae. Biochem. Biophys. Acta  1050: 155-159.

20. Nicholson, R., Pelletier, J., Le, S.-Y., and Sonenberg, N. (1991). Structural and Functional Analysis of the Ribosome Landing Pad of Poliovirus  type 2: In Vivo  Studies. J. Virology.  65 : 5886-5894.

21. Jaramillo, M., Pelletier, J., Edery, I., Nielsen, P.J., and Soneneberg, N. (1991). Multiple mRNAs Encode the Murine Translation Initiation Factor eIF-4E. J. Biol. Chem. 266: 10446-10451.

22. Call, K.M., T. Glaser, C.Y. Ito, A.J. Buckler, J. Pelletier, D.A. Haber, E.A. Rose, A. Kral, H. Yager, W.H. Lewis, C.A. Jones, and D.E. Housman. (1990). Description and Characterization of a Zinc Finger Polypeptide Gene at the Human Chromosome 11 Wilms' Tumor Locus. Cell  60: 509-520.

23. Haber, D.A., A.J. Buckler, T. Glaser, K.M. Call, J. Pelletier, R. L. Sohn, E.C. Douglass, and D.E. Housman. (1990). An Internal Deletion Within an 11p13 Zinc Finger Gene Contributes to the Development of Wilms' Tumor. Cell  61: 1257-1269.

24. Pritchard-Jones, K., S. Fleming, D. Davidson, W. Bickmore, D. Porteous, C. Gosden, J. Bard, A. Buckler, J. Pelletier, D. Housman, V. van Heyningen, and N. Hastie. (1990). The Candidate Wilms' Tumor gene is Involved in Genitourinary Development. Nature  346: 194-197.

25. Buckler, A.J., J. Pelletier, D.A. Haber, T. Glaser, and D.E. Housman. (1991). The Murine Homologue of the Wilms' Tumor Predisposition Gene and its Expression During Kidney Development. Mol. Cell. Biol.  11: 1707-1712.

26.  Pelletier, J., Brook, J.D., and Housman, D. (1991). Assignment of Two of the Translation Initiation Factor-4E (EIF-4E) Genes to Human Chromosomes 4 and 20. Genomics. 10: 1079-1082.

27. Pelletier, J., Schalling, M., Buckler, A.J.,  Haber, D.A., and Housman, D. (1991). The Wilms' Tumor Gene (WT1) is Involved in Genitourinary Development. Genes & Dev. 5: 1345-1357.

28. Haber, D.A., Sohn, R.L., Buckler, A.J., Pelletier, J., Call, K.M., and Housman, D. (1991). Alternative Splicing and Genomic Structure of the Wilms' tumor Gene WT1. Proc. Natl. Acad. USA. 88: 9618-9622.

29. Pelletier, J., Bruening, W., Li, F., Haber, D., Glaser, T., and Housman, D. (1991). WT1 Mutations Contribute to Abnormal Genital System Development and Hereditary Wilms' Tumour Nature  353: 431-434.

30.Pelletier, J., Bruening, W., Kashtan, C.E., Mauer, S.M., Manivel, J.C., Striegel, J.E., Houghton, D.C., Junien, C., Habib, R., Fouser, L., Fine, R.N., Silverman, B.L., and  Housman, D. (1991). Germline Mutations in the Wilms' Tumor Suppressor Gene Disrupt Urogenital Development in Humans. Cell. 67:437-447.

31. Bruening, W., Bardeesy, N.,Silverman, B.L., Cohn, R.A., Machin, G.A., Aronson, A.J.,  Housman, D., and  Pelletier, J. (1992) Germline intronic and exonic mutations in the Wilms’ tumour gene (WT1) affecting urogenital development. Nature Genetics. 1: 144-148.

32. Haber, D.A., Timmers, H.Th. Marc, Pelletier, J., Sharp, P.A., and Housman, D. (1992) A dominant mutation in the Wilms' tumor gene WT1 cooperates with the viral oncogene E1A in transformation of primary kidney cells. Proc. Natl. Acad. Sci. USA. 89: 6010-6014.

33. Bruening, W., Gros, P., Sato, T., Stanimir, J., Nakamura, Y., Housman, D., and Pelletier , J. (1993). Single-Strand Conformation Polymorphism (SSCP) Analysis of the Wilms' Tumor Suppressor Gene (WT1) in Ovarian Tumors. Cancer Investigations  11: 393-399.

34. Kreidberg, J.A., Sariola, H., Loring, J.M., Maeda, M., Pelletier, J., Housman, D., and Jaenisch, R. (1993) WT-1 is Required for Early Kidney Development. Cell  74: 679-691.

35. Coppes, M., Huff, V., and Pelletier, J. (1993)  Denys-Drash Syndrome: Relating a Clinical Disorder to Genetic Alterations in a Tumor Suppressor Gene. J. Pediatrics. 123: 673-678.

36. Vogan, K., Bernstein, M., Leclerc, J.-M., Brisson, L., Brossard, J., Brodeur, G.M., Pelletier, J., and Gros, P. (1993) Absence of p53 Gene Mutations in Primary Neuroblastomas. Cancer Res. 53: 5269-5273.

37. Mundlos, S., Pelletier, J., Darveau, A., Bachmann, M., Winterpacht, A., and Zabel, B. (1993) Nuclear localization of the protein encoded by the Wilms' tumor gene WT1 in embryonic and adult tissues. Development  119: 1329-1341.

38. Varanasi, R., Bardeesy, N. Ghahremani, M., Petruzzi, M.-J., Nowak, N., Adam, M.A., Grundy, P., Shows, T., and Pelletier, J. (1994) Fine Structure Analysis of the WT1 Gene in Sporadic Wilms' Tumors. Proc. Natl. Acad. Sci. USA. 91: 3554-3558

39. Bardeesy, N., Falkoff, D., Petruzzi, M.-J., Nowak, N., Zabel, B., Adam, M., Aguiar, M.C., Grundy, P., Shows, T., and Pelletier, J. (1994) Anaplastic Wilms' tumors - A subtype displaying poor prognosis harbors p53 gene mutations. Nature Genet. 7: 91-97.

40. Bardeesy, N., Zabel, B., Schmitt, K. and Pelletier, J. (1994) WT1 Mutations Associated With Incomplete Denys-Drash Syndrome Define a Domain Predicted to Behave in a Dominant-Negative Fashion. Genomics. 21: 663-665.

41. Bardeesy, N.,  Beckwith, J.B., and Pelletier, J. (1995) Clonal Expansion and Attenuated Apoptosis in Wilms' Tumors are Associated with p53 Gene Mutations. Cancer Res., 55: 215-219.

42. Nakagama, H., Heinrich, G., Pelletier, J. and Housman, J. (1995) DNA Binding Specificity of the Wilms' Tumor Gene Product, and its Modulation by Zinc Finger I and the Flanking DNA Subsites. Mol Cell Biol. 15: 1489-1498.

43. Goodyer, P., Dehbi, M.,Torban, E., Bruening, W., and Pelletier, J. (1995). Repression of the Retinoic Acid Receptor- Gene by the Wilms' Tumor Suppressor Gene Product, wt1. Oncogene  10: 1125-1129.

44. Edery, I., Chu, L.L., Sonenberg, N. and Pelletier J. (1995) An Efficient Strategy to Isolate Full-Length cDNAs Based on a mRNA Cap Retention Procedure (CAPture). Mol. Cell. Biol. 15: 3363-3371.

45. Gradi, A., Tang-Wai, R., McBride, H.M., Chu, L. L., Shore, G.C., and Pelletier, J. (1995) Molecular cloning and expression of the human Steroidogenic Acute Regulatory (StAR) protein. Biochem. Biophys. Acta. 1258: 228-233.

46. Schmitt, K., Zabel, B., Eitelberger, F., and Pelletier, J. (1995). Nephropathy with Wilms tumour or gonadal dysgenesis: incomplete Denys-Drash syndrome or separate diseases? Eur. J. Pediatr. 154: 577-581.

47. Moffett, P., Bruening, W., Nakagama, H., Bardeesy, N., Housman, D., Housman, D.E. and J. Pelletier. (1995) Antagonism of WT1 Activity by Self-Association. Proc. Natl. Acad. Sci. USA. 92: 11105-11109.

48. Li, F.P., Breslow, N., Morgan, J.M., Ghahremani, M., Miller, G.A., Grundy, P., Green, D., Diller, L.R., and Pelletier, J. (1996). Germline WT1 mutations in Wilms’ tumor patients: Preliminary Results. Medical and Pediatric Oncology 27: 404-407.

49. Bruening, W., and Pelletier, J. (1996). A non-AUG Translational Initiation Event Generates Novel WT1 Isoforms. J. Biol. Chem. 271: 8646-8654.

50. Mohammed, D., Ghahremani, M., Lechner, M., Dressler, G.,and Pelletier, J. (1996) The paired-box transcription factor, PAX2, positively modulates expression of the Wilms’ tumor suppressor gene (WT1). Oncogene 13: 447-453.

51. Fuqua, J.S., Sher, E.S., Perlman, E.J., Urban, M.D., Ghahremani, M., Pelletier, J., Migeon, C.J., Brown, T.R., and Berkovitz, G.D. (1996). Abnormal gonadal differentiation in two subjects with ambiguous genitalia, Mullerian structures, and normally developed testes: evidence for a defect in gonadal ridge development. Hum Genet. 97: 506-511.

52. Moffett, P., Dayo, M., Reece, M., McCormick, M.K., and Pelletier, J. (1996). Characterization of msim, a murine homologue of theDrosophila sim  transcription factor. Genomics 35: 144-155.

53. Rahman, N., Arbour, L., Tonin, P., Renshaw, J., Pelletier, J., Baruchel, S., Pritchard-Jones, K., Stratton, M.R., and Narod, S.A. (1996). Evidence for a familial Wilms’ tumour gene (FWT1) on chromosome 17q12-q21. Nature Genet. 13: 461-463.

54. Bruening, W., Moffet, P., Chia, S., Heinrich, G., and Pelletier, J. (1996). Identification of nuclear localization signals within the zinc fingers of the WT1 tumor suppressor gene product. FEBS Letters 393: 41-47.

55. Dehbi, M., and Pelletier, J. (1996). PAX8-Mediated Activation of the wt1 Tumor Suppressor Gene. EMBO J. 15:  4297-4306.

56. Ghahremani, M., Chan, C.-B., Bistritzer,T., Aladjem, M., Tieder, M., and J. Pelletier (1996) A Novel Mutation in the Wilms’ Tumor Suppressor Gene, WT1, Associated with Denys-Drash Syndrome. Hum. Heredity  46: 336-338.

57. Kaplinsky, C., Ghahremani, M., Frishberg, Y., Rechavi, G., and Pelletier, J. (1996). Familial Wilms’ tumor associated with a WT1 zinc finger mutation. Genomics 38: 451-453.

58. Moffett, P., Reece, M., and Pelletier, J. (1997). The murine Sim-2 gene product inhibits transcription by active repression and functional interference. Mol. Cell. Biol. 17: 4933-4947.

59. Vicanek, C., Ferretti, E., Goodyer, C., Torban, E., Moffett, P., Pelletier, J., and Goodyer, P. (1997). Regulation of renal EGF receptor expression is normal in Denys-Drash syndrome. Kid. Int. 52: 614-619.

60. Rodriguez, P., Munroe, D., Prwitt, D., Chu, L.L., Bric, E., Kim, J., Reid, L.H., Davies, C., Nakagama, H., Loebbert, R., Winterpacht, A., Petruzzi, M.-J., Higgins, M.J., Nowak, N., Evans, G., Shows, T., Weissman, B.E., Zabel, B., Housman, D., and Pelletier, J. (1997). Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suugests a role as a histone chaperone.Genomics 44: 253-265.

61. Discenza, M.T., Dehbi, M., and Pelletier, J. (1997) Overlapping DNA Recognition Motifs Between Sp1 and a Novel Trans-Acting Factor within the wt1 Tumor Suppressor Gene Promoter. Nucleic Acids Research 25: 4314-4322.

62. Das, M., Chu, L.L., Ghahremani, M., Abrams-Ogg, T., Roy, M.S.,  Housman, D.,  and Pelletier, J. (1997). Characterization of an Abundant Short Interspersed Nuclear Element (SINE) Present in Canis familiaris. Mammalian Genome 9: 64-69.

63. Kim, J., Lee, K., and Pelletier, J. (1998). The DNA Binding Domains of the WT1 Tumor Suppressor Gene Product and Chimeric EWS/WT1 Oncoprotein Are Functionally Distinct. Oncogene 16: 1021-1030.

64. Kim, J., Lee, K., and Pelletier, J. (1998). The desmoplastic small round cell tumor t(11;22) translocation produces EWS/WT1 isoforms with different oncogenic properties. Oncogene 16: 1973-1979.

65. Bardeesy, N. and Pelletier, J. (1998). Overlapping RNA and DNA binding domains of the wt1 tumor suppressor gene product. Nucl. Acids Res. 26: 1784-1792.

66. Dehbi, M., Hiscott, J., and Pelletier, J. (1998). Activation of the wt1 Wilms’ tumor suppressor gene by NF-kB. Oncogene 16: 2033-2039.

67. Chu, L.L., Rutteman, G.R., Kong, J.M.C., Ghahremani, M., Schmeing, M., Misdorp, W., van Garderen, E., and Pelletier, J. (1998). Genomic organization of the canine p53 gene and its mutational status in canine mammary neoplasia. Breast Cancer Res. & Treatment  50: 11-25.

68. Cooper, P.R., Smilnich, N.J., Day, C.D., Nowak, N.J., Reid, L.H., Pearsall, R.S., Reece, M., Prawitt, D., Landers, J., Housman, D.E., Winterpacht, A., Zabel, B.U., Pelletier, J., Weissman, B.E., Shows, T.B., and Higgins, M.J. (1998). Divergently transcribed overlapping genes expressed in liver and kidney and located in the 11p15.5 imprinted domain. Genomics 49: 38-51.

69. Diller, L., Ghahremani, M., Morgan, J., Grundy, P., Reeves, C., Breslow, N., Green, D., Neubergm D., Pelletier, J., and Li, F.P. (1998). Constitutional WT1 mutations in Wilms’ tumor patients. J. Clin. Oncol. 16: 3634-3640. 71. Reece, M., Prawitt, D., Landers, J., Kast, C., Gros, P., Housman, D., Zabel, B.U., and Pelletier, J. (1998) Functional characterization of ORCTL2 – an organic cation transporter expressed in the renal proximal tubules. FEBS Lett. 433: 245-250.

70. Reece, M., Prawitt, D., Landers, J., Kast, C., Gros, P., Housman, D., Zabel, B.U., and Pelletier, J. (1998) Functional characterization of ORCTL2 – an organic cation transporter expressed in the renal proximal tubules. FEBS Lett. 433: 245-250.

71. Kim, J., Prawitt, D., Bardeesy, N., Torban, E., Vicaner, C., Goodyer, P., Zabel, B.,  and Pelletier, J. (1999). The Wilms’ Tumor Suppressor Gene (wt1) Product Regulates Dax-1 Gene Expression During Gonadal Differentiation. Mol. Cell. Biol. 19: 2289-2299.

72. Lee, T.H., Moffett, P., and Pelletier, J. (1999) The Wilms tumor suppressor gene (wt1) product represses different functional classes of transcriptionala activation domains. Nucl. Acids Res. 27: 2889-2897.

73. Kim, J., Lee, J.M., Branton, P.E., and Pelletier, J. (1999). Modification of EWS/WT1 functional properties by phosphorylation. Proc. Natl. Acad. Sci. 96: 14300-14305.

74. Prawitt, D., Enklaar, T., Klemm, G., Gaertner, B., Spangenberg, C., Winterpacht, A., Higgins, M., Pelletier, J., and Zabel, B. (1999) Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression. Hum. Mol. Genet. 9: 203-216.

75. Moffett, P., and Pelletier, J. (2000). Differential transcriptional properties of mSim-1 and mSim-2. FEBS Letters 466: 80-86.

76. Rodriguez, P., Pelletier, J., Price, G., and Zannis-Hadjopoulos, M. (2000). NAP-2: Histone chaperone function and phosphorylation state through the cell cycle. J. Mol. Biol. 298: 225-238.

77. Kim, J., Lee, J.M., Branton, P.E., and Pelletier, J. (2000). Modulation of EWS/WT1 activity by the v-Src protein tyrosine kinase. FEBS Lett. 474: 121-128.

78. Das, M., Sakul, H., Kong, J., Acland, G., and Pelletier, J., (2000). A Set of Canine Inter-repeat Sequence PCR Markers for High Throughput Genotyping. Physiol. Genomics 4: 13-24.

79. Das, M., Burge, C., Park, E., Colinas, J., and Pelletier, J. (2001). Assessment of the total number of human transcription units. Genomics. 77: 71-78.

80. Lee, T.H., and Pelletier, J. (2001). Functional characterization of WT1 binding sites within the human vitamin D receptor gene promoter. Physiol. Genomics. 7: 187-200.

17. Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donze O, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M Jr, Gehrke L, Goldman E, Groner Y, Harford JB, Hatzglou M, He B, Hellen CU, Hentze MW, Hershey J, Hershey P, Hohn T, Holcik M, Hunter CP, Igarashi K, Jackson R, Jagus R, Jefferson LS, Joshi B, Kaempfer R, Katze M, Kaufman RJ, Kiledjian M, Kimball SR, Kimchi A, Kirkegaard K, Koromilas AE, Krug RM, Kruys V, Lamphear BJ, Lemon S, Lloyd RE, Maquat LE, Martinez-Salas E, Mathews MB, Mauro VP, Miyamoto S, Mohr I, Morris DR, Moss EG, Nakashima N, Palmenberg A, Parkin NT, Pe'ery T, Pelletier J, Peltz S, Pestova TV, Pilipenko EV, Prats AC, Racaniello V, Read GS, Rhoads RE, Richter JD, Rivera-Pomar R, Rouault T, Sachs A, Sarnow P, Scheper GC, Schiff L, Schoenberg DR, Semler BL, Siddiqui A, Skern T, Sonenberg N, Tahara SM, Thomas AA, Toulme JJ, Wilusz J, Wimmer E, Witherell G, Wormington M. (2001) New ways of initiating translation in eukaryotes. Mol. Cell. Biol. 21, 8238-8246.

81. Harvey, I., Garneau, P., Pelletier, J. (2002). Forced engagement of a RNA/protein complex by a chemical inducer of dimerization to modulate gene expression . Proc. Natl. Acad. Sci. USA 99: 1882-1887.

82. Cai, J., Daoud, R., Alqawi, O., Georges, E., Pelletier, J., and Gros, P. (2002). Nucleotide binding and nucleotide hydrolysis properties of the ABC transporter MRP6(ABCC6). Biochemistry 41: 8058-8067.

83. Harvey, I., Garneau, P., Pelletier, J. (2002). Inhibition of translation by RNA-small molecule interactions. RNA. 8: 452-463.

84. Carriere, M., Applefield, D., Harvey, I., Garneau, P., Lorsch, J., Lapidot, A., and Pelletier, J. (2002) Inhibition of protein synthesis by aminoglycoside-arginine conjugates. RNA 8: 1267-1279.

85. Lee, T., Lwu, S., Kim, J.,  and Pelletier, J. (2002). Interference of the Wilms’ Tumour 1 (WT1) Transactivation Potential by Bone Marrow Zinc Finger 2, a Novel Transcriptional Repressor.  J. Biol. Chem. 277: 44826-44837.

86. Lee, J., Park, E.H., and Pelletier, J. (2002) An Upstream Open Reading Frame Impedes Translation of the Huntingtin Gene. Nucl. Acids Res. 30: 5110-5119.

87. Discenza, M.T., He, S., Lee, T. H., Chu, L.L., Bolon, B., Goodyer, P., Eccles, M. and Pelletier, J. (2003). WT1 is a Modifer of the Pax2 Mutant Phenotype: Cooperation and Interaction Between WT1 and Pax2. Oncogene 22: 8145-8155.

88. Liu, J., Dehbi, M., Moeck, G., Arhin, F., Bauda, P., Bergeron, D., Callejo, M., Ferretti, V., Ha, N., Kwan, T., McCarty, J., Srikumar, R., Williams, D., Wu, J., Gros, P., Pelletier, J., and DuBow, M. (2004) Antimicrobial drug discovery from bacteriophage genomics.  Nat. Biotech. 22: 185-191.

89. Wang. B., Pelletier, J., Massaad, M.J., Herscovics, A., and Shore, G.C. (2004). The yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like B. Mol. Cell. Biol. 24: 2767-2778.

90. Discenza, M.T., Vaz, D., Hassell, J., and Pelletier, J. (2004). Activation of the WT1 tumor suppressor gene promoter by Pea3. FEBS Letters 560, 183-191.

91. Chan, J., Khan, S.N., Harvey,  I., Merrick, W., and Pelletier, J. (2004) Novel Eukaryotic Protein Synthesis Inhibitors Identified by  Comparison of Cytotoxicity Profiles. RNA 10, 528-543.

92. Novac, O., Guenier, A.-S., and Pelletier, J. (2004). Inhibitors of protein synthesis identified by a high throughput multiplexed translation screen. Nucl. Acids Res. 32: 902-915.

93. Itoh, A., Tanahashi, T., Nagakura, N., Takenaka, Y., Chen, C.-C., and Pelletier, J. (2004) Flavonoid glycosides from Adina racemosa and their inhibitory activities on eukaryotic protein synthesis. J. Nat. Prod. 67: 427-431.

94.  Lee, H.J., Kim, S., Pelletier, J., and Kim, J. (2004). Stimulation of hTAFII68 (NTD)-mediated transactivation by v-src. FEBS Letters 564: 188-198.

95. Wendel, H.-G., de Stanchina, E., Fridman, J., Malina, A., Ray, S., Kogan, S., Cordon-Cardo, C., Pelletier, J., and Lowe, S. (2004). Survival signaling by Akt and eIF4E in oncogenesis and cancer therapy. Nature 428: 332-337.

96. Muhammad, I., Bedir, E., Khan, S.I., Tekwani, B.L. Khan, I.A., Takamatsu, S., Pelletier, J., and Walker, L.A. (2004). A new antimalaria quassinoid from Simaba orinocensis. J. Nat. Prod. 67: 772-777.

97. Kumar, R., Garneau, P., Nguyen, N., Lown, J.W., and Pelletier, J. (2004). Methionine substituted polyamides are RNAse mimics that inhibit translation. J. Drug. Target. 12: 125-134.

98. Fukamiya, N., Lee, K.-H., Muhammad, I., Murakami, C., Okano, M., Harvey, I., and Pelletier, J. (2005). Structure-activity relationships of quassinoids for eukaryotic protein synthesis. Canc. Lett. 220: 37-48.

99. Malina, A., Khan, S., Carlson, C.B., Svitkin, Y., Harvey, I., Sonenberg, N., Beal, P., and Pelletier, J. (2005). Inhibitory properties of nucleic acid-binding ligands on protein synthesis. FEBS Lett. 579: 79-89.

100. Prawitt, D., Enklaar, T., Gartner-Rupprecht, B., Spangenberg, C., Fees, S., Lucito, R., Reutzel, D., Brozek, I., Limon, J., Pelletier, J., and Zabel, B. (2005). Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor. Proc. Natl. Acad. Sci USA 102: 4085-4090.

101.  Kwan, T., Liu, J., Dubow, M., Gros, P., Pelletier, J. (2005) The complete genomes and proteomes of 27 Staphylococcus aureus bacteriophages. Proc. Natl. Acad. Sci USA 102: 5174-5179.

102. Hamdan, F.F., Audet, M., Garneau, P., Pelletier, J., and Bouvier, M. (2005). High-throughput screening of G protein-coupled receptors antagonists using a BRET1-based -arrestin2 recruitment assay. J. Biomolecular Screening. 10: 463-475.

103. Park, E., Lee, J.M., Blais, J.D., Bell, J.C., and Pelletier, J. (2005). Internal translation initiation mediated by the angiogenic factor Tie2. J. Biol. Chem. 280:  20945-20953.

104. Bordeleau, M.-E., Matthews, J., Wojnar, J.M., Lindqvist, L., Novac, O., Jankowsky, E., Sonenberg, N., Northcote, P., Teesdale-Spittle, P., and Pelletier, J. (2005) Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation. Proc. Natl. Acad. Sci. USA 102: 10460-10465.

105. Yan, Y., Svitkin, Y., Lee, J.M., Bisaillon, M., and Pelletier, J. (2005). Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap. RNA 11; 1238-1244.

106. Kwan, T., Liu, J., DuBow, M., Gros, P. and Pelletier, J. (2006). Comparative Genomic Analysis of 18 Pseudomonas aeruginosa Bacteriophages. J. Bact. 188: 1184-1187

107. Park, E.-H., Lee, J.M., and Pelletier, J. (2006). The Tie2  5’ Untranslated Region is Inhibitory to  5’ end-Mediated Translation Initiation. FEBS Letters. 580: 1309-1319.

108. Petersen, C.P., Bordeleau, M.-E., Pelletier, J., and Sharp, P. (2006). Short RNAs repress translation after initiation in mammalian cells. Mol. Cell. 21: 533-542.

109. Bordeleau, M.-E., Mori, A., Oberer, M., Lindqvist, L., Higa, T., Belsham, G., Wagner, G., Tanaka, J., and Pelletier, J. (2006). Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A. Nat. Chem. Biol. 2: 213-220.

110. Chard, L.S., Bordeleau, M.E., Pelletier, J., Tanaka, J., and Belsham, G.J. (2006) Hepatitis C virus-related internal ribosome entry sites are found in multiple genera of the family Picornaviridae. J. Gen. Virol. 87: 927-936.

111. Robert, F., Gao, H.Q., Donia, M., Merrick, W.C., Hamann, M.T., and Pelletier, J. (2006). Chlorolissoclimides: New inhibitors of eukaryotic protein synthesis. RNA 12: 717-724.

112. Malo, N., Hanley, J.A., Cerquozzi, S., Pelletier, J., and Nadon, R. (2006). Statistical practice in high-throughput screening data analysis. Nat. Biotech. 24: 167-175.

113. McKay, G.A., Reddy, R., Arhin, F., Belley, A., Lehoux, D., Moeck, G., Sarmiento, I., Parr, T.R., Gros, P., Pelletier, J., and Far, A.R. (2006) Triaminotriazine DNA helicase inhibitors with antibacterial activity. Bioorg. & Med. Chem. Lett. 16: 1286-1290.

114. Arhin, F., Belanger, O., Ciblat, S., Dehbi, M., Delorme, D., Dietrich, E., Dixit, D., Lafontaine, Y., Lehoux, D., Liu, J., McKay, G.A., Moeck, G., Reddy, R., Rose, Y., Srikumar, R., Tanaka, K.S.E., Williams, D.M., Gros, P., Pelletier, J., Parr, T.R., and Far, A.R. (2006) A new class of small molecule RNA polymerase inhibitors with activity against Rifampicin-resistant Staphylococcus aureus. Bioorg. & Med. Chem. Lett. 14: 5812-5832.

115. Chaudhry, Y., Nayak, A., Bordeleau, M.E., Tanaka, J., Pelletier, J., Belsham, G.J., Roberts, L.O., and Goodfellow, I.G. (2006). Caliciviruses differ in their functional requirements for eIF4F components. J.Biol. Chem. 281, 25315-25325

116. Mazroui, R., Sukarieh, R., Bordeleau, M.E., Kaufman, R.J., Northcote, P., Tanaka, J., Gallouzi, and Pelletier, J. (2006). Inhibition of ribosome recruitment induces stress granule formation independent of eIF2a phosphorylation.  Mol. Biol. Cell. 17: 4212-4219.

117. Wendel, H.-G., Malina, A., Zhao, Z., Zender, L., Kogan, S.C., Cordon-Cardo, C., Pelletier, J., and Lowe, S.W. (2006). Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations  in vivo. Cancer Res. 66: 7639-7646.

118. Robert, F., Kapp, L.D., Khan, S.N., Acker, M.G., Kolitz, S., Kazemi, S., Kaufman, R.J., Merrick, W.C., Koromilas, A.E., Lorsch, J.R., and Pelletier, J. (2006). Initiation of protein synthesis by Hepatitis C virus is refractory to reduced eIF2•GTP•Met-tRNAiMet ternary complex availability. Mol. Biol. Cell. 17: 4632-4644.

119. Belley, A., Callejo, M., Arhin, F., Dehbi, M., Fadhil, I., Liu, J., McKay, G., Srikumar, R., Bauda, P., Bergeron, D., Ha, N., DuBow, M., Gros, P., Pelletier, J., and Moeck, G. (2006) Competition of bacteriophage polypeptides with native replicase proteins for binding to the DNA sliding clamp reveals a novel mechanism for DNA replication arrest in Staphylococcus aureus. Mol. Microbiol. 62: 1132-1143.

120. Spevak CC, Park EH, Geballe AP, Pelletier J, Sachs MS. (2006). her-2 upstream open reading frame effects on the use of downstream initiation codons. Biochem Biophys Res Commun. 350: 834-841.

121. Bordeleau ME, Cencic R, Lindqvist L, Oberer M, Northcote P, Wagner G, Pelletier J. (2006) RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation. Chem Biol. 13: 1287-1295.

122. Watts JK, Choubdar N, Sadalapure K, Robert F, Wahba AS, Pelletier J, Mario Pinto B, Damha MJ. (2007) 2'-Fluoro-4'-thioarabino-modified oligonucleotides: conformational switches linked to siRNA activity. Nucleic Acids Res.  35: 1441-1451

123. Akimitsu, N., Tanaka, J., and Pelletier, J. (2007). Translation of nonSTOP mRNA is repressed post-initiation in mammalian cells. EMBO J. 26: 2327-2338

124. Cencic. R., Yan, Y., and Pelletier, J. (2007). Homogenous time resolved fluorescence assay to identify modulators of cap-dependent translation initiation. Combinatorial Chemistry & High Throughput Screening. 10: 181-188.

125. Costa-Mattioli, M., Gobert, D., Stern, E., Gamache, K., Colina, R., Cuello, C., Sossin, W., Kaufman, R., Pelletier, J., Rosenblum, K., Krnjevic, K., Lacaille, J.-C. Nader, K., and Sonenberg, N. (2007) eIF2a phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell 129: 195-206.

126. Kazemi, S., Mounir, Z., Baltzis, D., Raven, J.F., Wang, S., Krishnamoorthy, J.L.,  Pluquet, O., Pelletier, J., and Koromilas, A.E. (2007). A novel function of eIF2a kinases as inducers of the phosphoinositide-3-kinase signaling pathway. Mol. Biol. Cell. 18: 3635-3644.

127. Gerard, B., Cencic, R., Pelletier, J., and Porco, J.A., Jr. (2007). Enantioselective synthesis of the complex rocaglate (-)-silvestrol. Angew. Chem. Int. Ed. Engl. 46: 7831-7834.

128. Wendel, H.G., Silva, R.L., Malina, A., Mills, J.R., Zhu, H., Ueda, T., Watanabe-Kukunaga, R., Fukunaga, R., Teruya-Feldstein, J., Pelletier, J., and Lowe, S. (2007) Dissecting eIF4E action in tumorigenesis. Genes Dev. 21: 3232-3237.

129. Lindqvist, L., Imataka, H., and Pelletier, J. (2008). Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking. RNA 14: 960-969.

130. Lindqvist, L., Oberer, M., Reibarkh, M., Cencic, R., Bordeleau, M.-E., Vogt, E., Marintchev, A., Tanaka, J., Fagotto, F., Altmann, M., Wagner, G., and Pelletier, J. (2008). Selective Pharmacological Targeting of a DEAD box RNA helicase. PLOS ONE. 3: e1583.

131. Rong, L., Livingstone, M., Sukarieh, R., Petroulakis, E., Gingras, A.-C. G., Crosby, K., Smith, B., Polakiewicz, R.D., Pelletier, J., Ferraiuolo, M.A., and Sonenberg, N. (2008). Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs. RNA 14: 1318-1327.

132. Mills, J.R., Hippo, Y., Robert, F., Chen, S.M.H., Malina, A., Lin, C.-J., Trojahn, U., Wendel, H.-G., Charest, A., Bronson, R.T., Kogan, S.C., Nadon, R., Housman, D., Lowe, S.W., and  Pelletier, J. (2008). mTORC1 promotes survival through translational control of Mcl-1. PNAS 15: 10853-10858.

133. Lin, C.-J., Cencic, R., Mills, J., Robert, F., and Pelletier, J. (2008). c-Myc and eIF4E are components of a Feedforward Loop that Link Transcription and Translation. Cancer Res., 68: 5326-5334

134. Bordeleau, M.E., Robert, F., Gerard, B., Lindqvist, l., Wendel, H.-G., Brem, B., Greger, H., Lowe, S.W., Porco Jr, J.A., and Pelletier, J. (2008) Therapeutic suppression of translation initiation reverses chemoresistance. J. Clin. Inv., 118: 2651-2660.

135. Mavrakis, K.J., Zhu, H., Silva, R.L., Mills, J.R., Teruya-Feldstein, J., Lowe, S., Tam, W., Pelletier, J., and Wendel, H.G. (2008). Tumorigenic activity and therapeutic inhibition of Rheb GTPase. Genes & Dev. 22: 2178-2188.

136. Gravel, M., Robert, F., Kottis, V., Gallouzi, I.-E., Pelletier, J., and Braun, P. (2009) 2’3’-cyclic nucleotide 3’-phosphodiesterase – A novel RNA-binding protein that inhibits protein synthesis. J. Neurosci. Res. 87:1069-1079.

137. Vázquez, G.C., Lindqvist, L., Harvey, I., and Pelletier, J. (2009). High-throughput assays probing Protein:RNA interactions of eukaryotic translation  initiation factors. Anal. Bioch. 384:180-188.

138. Ran, I., Laplante, I., Bourgeois, C., Pépin, J., Lacaille, P., Costa-Mattioli, M., Pelletier, J., Sonenberg, N., and Lacaille, J.-C., (2009) Persistent transcription- and translation-dependent long-term potentiation induced by mGluR1 in hippocampal interneurons.  J. Neurosci. 29: 5605-5615.

139. Beutler, J.A., Kang, M.-I., Robert, F., Clement, J.A., Pelletier, J., Colburn, N.H., McKee, T.C., Goncharova, E., McMahon, J.B., and Henrich, C.J. (2009). Quassinoid inhibition of AP-1 function does not correlate with cytotoxicity or protein synthesis inhibition.  J. Natl. Prod. 72: 503-506.

140. Sukarieh, R., Sonenberg, N., and Pelletier, J. (2009) The eIF4E binding proteins (4E-BPs) are modifiers of cytoplasmic eIF4E relocalization during the heat shock response. Am. J. Physiol Cell Physiol. 296: C1207-1217.

141. Lin, C.-J., Sukarieh, R., and Pelletier, J. (2009) Silibinin inhibits translation initiation: Implications for anticancer therapy. Mol. Cancer Ther. 8: 1606-1612.

142. Cencic, R., Carrier, M., Galicia Vazquez, G., Bordeleau, M.-E., Sukarieh, R., Bourdeau, A., Brem, B., Teodoro, J.G., Greger, H., Tremblay, M., Porco, J., and Pelletier, J. (2009) Antitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol. PloS One, 4:e5223.

143. Robert, F., Williams, C., Yan, Y., Donohue, E.,  Cencic, R., Burley, S.K., and Pelletier, J. (2009) Blocking UV-induced eIF2a phosphorylation with small molecule inhibitors of GCN2. Chem Biol. Drug Des. 74: 57-67.

144. Robert, F., Carrier, M., Rawe, S., Chen, S., Lowe, S., and Pelletier, J. (2009) Altering chemosensitivity by modulating translation elongation. PloS One, 4: e5428.

145. Mokas, S., Mills, J.R., Garreau, C., Fournier, B., Robert, F., Arya, P., Kaufman, R.J., Pelletier, J., and Mazroui, R. (2009) Uncoupling Stress Granule assembly and translation 146. initiation inhibition. Mol. Biol. Cell. 20: 2673-2683.

146. Dehbi M, Moeck G, Arhin FF, Bauda P, Bergeron D, Kwan T, Liu J, McCarty J, Dubow M, Pelletier J. (2009) Inhibition of transcription in Staphylococcus aureus by a primary sigma factor-binding prolypeptide from phage G1. J. Bacteriol. 191: 1761-1771.

147. Cencic, R., Carrier, M., Trnkus, A., Porco Jr, J.A., Minden, M., and Pelletier, J. (2009) Synergistic effect of inhibiting translation initiation in combination with cytotoxic agents in acute myelogenous leukemia cells. Leukemia Res. Epub ahead of print.

B) Book Chapters and Reviews

1. Sonenberg, N., I. Edery, G. Sarkar, and J. Pelletier. (1986). Eukaryotic mRNA Cap Binding Protein Complex and 5' mRNA Secondary Structure: Studies in Uninfected and Poliovirus-Infected Cells. In "Current Communications. Molecular Biology - Translational Control." (Mathews, M.B., ed.) Cold Spring Harbor Laboratory, New York pp. 30-34.

2. Pelletier, J. and N. Sonenberg. (1987). The Involvement of mRNA Secondary Structure in Protein Synthesis. Biochem. Cell. Biol. 65: 576-581.

3. Edery, I., J. Pelletier, and N. Sonenberg. (1987). Role of Eukaryotic RNA Cap-Binding Protein in Regulation of Translation. In "Translational Regulation of Gene Expression." (Ilan, J., ed.) Plenum Press, New York, pp. 335-366.

4. Sonenberg, N. and J. Pelletier. (1989). Poliovirus Translation: A Paradigm for a Novel Initiation Mechanism. Bioessays  11:  128-132.

5. Meerovitch, K., J. Pelletier, and N. Sonenberg. (1990). The Translation of Picornaviruses. In "Translation in Eukaryotes" (Trachsel, H., ed.)

6. Pelletier, J., Haber, D., and Housman, D. (1991). Genetics of Wilms' Tumor. In "Origins of Human Cancer". (J. Brugge, T. Curran, E. Harlow, F. McCormick, eds.) Cold Spring Harbor Laboratory Press, N.Y.

7. Pelletier, J., Munroe, D., and Housman, D.(1991). Molecular Genetics of Wilms' Tumor. In 'Genome Analysis Vol 3: Genes & Phenotypes'. Cold Spring Harbor Laboratory Press, N.Y. pp 135-169.

8. Lowe, S.W., Bodis, S., Bardeesy, N., McClapchey, A., Remington, L., Ruley, H.E., Fischer, D.E., Jacks, T., Pelletier, J., and Housman, D. (1994) Apoptosis and the prognostic significance of p53 Mutations. In Cold Spring Harbor Symposia on Quantitative Biology. (Cold Spring Harbor Laboratories). Vol 59. pp. 419-426.

9. Pelletier, J. (1994)  Molecular Genetics of Wilms' Tumor - Insights into Normal and Abnormal Renal Development. Can. J. Oncol.  4(2), 262-272.

10. Bruening, W. and Pelletier, J. (1994) Denys-Drash syndrome: A role for the WT1 tumor suppressor gene in urogenital development. Seminars in Developmental Biology  5: 333-343.

11. Bruening, W., Winnett, E., and Pelletier, J. (1995) Wilms' tumor: A paradigm for insights into development and cancer. Cancer Investigations. 13(4): 431-443.

12. Bardeesy, N. and Pelletier, J. (1995) Mutational Detection by Single Strand Conformational Polymorphism.  In  “PCR in Neuroscience.” (G. Sarkar, ed.) [Academic Press, New York] p.163-183.

13. Pelletier, J., Nakagama, H., and Housman, D. (1996). Cancer Genes: Functional Aspects. (ed. H. Mihich and D. Housman). Pezcoller Foundation Symposia. Vol. 7, pp. 103-122.

14. Pelletier, J. (1996). Affinity Selection of Eukaryotic mRNAs and Full-length cDNAs by a Cap Retention Procedure (CAPture). In “Gene Cloning and Analysis”. (B.C. Schaefer, ed.) [Horizon Scientific Press] p. 81 - 98.

15. Kim, J. and Pelletier, J. (1999). Molecular genetics of chromosome translocations involving EWS and related family members. Physiol. Genomics 1, 127-138.

16. Das, M., Harvey, I., Chu, L.L., Sinha, M., and Pelletier, J. (2001). Full-length cDNAs: more than just reaching the ends. Physiol. Genomics 6: 57-80.

17. Discenza, M., and Pelletier, J. (2004). Insights into the physiological role of WT1 from studies of genetically modified mice. Physiol. Genomics 16: 287-300.

18. Pelletier, J. and Peltz, S.W. (2006). Therapeutic Opportunities in Translation. In “Translational Control in Biology and Medicine” (Matthews, M., Sonenberg, N., and Hershey,  J.W.B.).

19. Cencic, R., Robert, F., and Pelletier, J. (2007). Identifying small molecule inhibitors of eukaryotic translation initiation. Methods in Enzymology. 431: 269-302.

20. Pelletier, J., Mazroui, R., Sukariah, R., Harvey, I., and Gallouzi, I. (2008). “Stress Granules in Cell Survival.” In RNA Binding Proteins in Development and Disease. “ [ed. Robert B. Denman] p.13-33.

21. Robert, F., and Pelletier, J. (2009). Translation Initiation: A critical signalling node in cancer. Expert Opin. Ther. Targets.13: 1279-1293.

22. Lin, C.-J., Malina, A., and Pelletier, J. (2009). C-Myc and eIF4E constitute a feedforward loop that regulates cell growth: Implications for anti-cancer therapy. Cancer Res. 69: 7491-7494.

23. Lindqvist, L., and Pelletier, J. (2009). Translating protein synthesis inhibitors into Cancer Therapeutics. Future Medicinal Chemisty. In Press.