This international network was formed in 1976 to encourage research, development and clinical

applications in artificial cells, blood substitutes, nanomedicine, regenerative medicine, tissue engineering, cell/stem cell therapy, hemoperfusion, bioencapsulation, and related areas.


We have avoided a tight and restrictive organizational structure. Instead responsibilities are widely

distributed to committees and organizers of congresses and symposia. This allows this society to benefit

from fresh ideas and novel approaches and to move with the frontier of research. This, plus the enthusiastic participation and voluntary contribution of members of the society, has allowed us to continue this

international network for nearly 50 years without charging membership fees – this allows for world-wide participation with no restrictions related to nationality, age, experience, financial status. This also avoid

any one group or groups from controlling the network or preventing it from moving in the frontier of research.




Elected Honorary President and coordinator: T.M.S.Chang (McGill, Canada)


Elected Executive committee (Elected Past-Presidents of of ISABI congresses and/or symposia):

V.Bonamini(Italy)1978; L.Bulow (Sweden), 2015; C.U.Casciani(Italy)1990; T.M.S.Chang(Canada)1976,

1987, 1991,1996, 2017); ; K. Kobayashi(Japan) 2003; R.Langer (USA) 1994;  Qin Liu (China) 2007; A. Mozzarelli  (Italy); Nikolaev(USSR) 1986;  E.Piskin(Turkey)1982,2001;  A.Trevino Becerra(Mexico) 1985, 2000; ; C.M.Yang(China), 1997;  Yang/Sakai (2019).WM Zapol (USA), 2011: Zheng/Yang/Liu (China) 2013

[Late Prof D.  Falkenhagen (Austria); Late Prof AG.Greenburg (USA) 2005; Late Prof M.Odaka (Japan); Late Prof S.Sideman(Israel);  Late Prof E.Tsuchida (Japan); Late Prof R.Winslow (USA): Late Prof Y.T.Yu(China)]


Subcommittee of ISABB: International Committee on Blood Substitutes ISBS:


ISBS Executive board members (past elected ISBS presidents or their representatives):

1987: Chang (1987, 1991,1996, 2017)

1993: Keipert (for late Winslow 1993, 1999)

1997: Yang/Yu YT (1997)

1997: Sakai (for late Tsuchida 1997)

2003: Kobayashi (2003)

2005: Late Greenberg (2005)

2007: Liu/Xiu (2007)

2009: Mozzarelli (2009)

2011: Binglan Yu for Late Prof Zapol (2011)

2013: Zheng/Liu/Yang (2013)

2015: Leif Bülow (2015)

2017: Chang (2017)

2019:  Yang/Sakai (2019)


ISBS Scientific Advisory Board

Alayash A, Abuchowski A. Baumler,H, Bian Y, Biro B, Bucci E, Bülow L, Burhop K, Chang TMS, Chen C, Cooper C, D’Agnillo F, Estep T, Feola M, Gould S, , Han JQ, Hong Z, Intaglietta M, Jahr J, Keipert P, Kim HW, Kluger R, Kobayashi K, Krafft MP, Liu Q, Liu JX, Ma L, Meßmer K, Mozzarelli A, Palmer A, Privalle C, Pugach I, Rausch C,  Riess JG,  Sakai H, Simoni, Selivanov E, Su ZG,  Tsai AG,  Wei G, Wong B, Wong JT, Xiu RJ, Yang CM, Yu BL, Zafiris G , Zal . Zapol W, Zhang Y, Zhao L, Zhu YJW



The emphasis is to concentrate on 1 or 2 areas that need extensive effort towards routine clinical uses. Once

the area is in routine clinical use, the area is left to other groups to look after and we then concentrate on another

1 to 2 areas that needs major effort. Each congress or symposium president in consultation with his local organizing committee, makes the final decision and has the final responsibilities including financial responsibilities. After each congress or symposium, the president or appointed representative becomes a member of the executive committee of the ISABI.

I     1976 ISABI (I HPS Hemoperfusion HP) President: TMS Chang (McGill, Canada)

II    1978 ISABI (II HPS) President: V Bonamini (Bologna U, Italy)  co-chair TMS Chang (McGill Canada) 

III   1980 ISABI (III HPS) President: S. Sideman (Technion, Israel) co-chair TMS Chang (McGill Canada)

IV   1982 ISABI (IV HPS)   President:  E. Piskin (Ankara U, Turkey)  Honorary President: TMS Chang(Canada)

V    1983 ISABI (V HPS)   President: C Z Huang (President, Chinese Academy of Medical Sciences),

      co-chair TMS Chang (McGill Canada)

VI   1985 ISABI (VI HPS) President: A. Trevino Becerra (Mexico).  Honorary President: TMS Chang (Canada)

VII  1986 ISABI  (VII HPS)   President: V.Nikolaev(USSR Academy of Sci), Honorary President: TMS Chang

VIII 1987 ISABI (III ISBS) President: TMS Chang (McGill, Canada), Cochair: R.Geyer (Harvard) 1987

IX   1988 ISABI (VIII HPS) President: D.Falkenhagen & Klinkmann(Germany) Honorary President:TMS Chang

X    1989  ISABI (VIV HPS)  President: M.Odaka(Chiba U, Japan), Honorary President: TMS Chang

XI   1990 ISABI (X HPS): President: C.U.Casciani(Rome U, Italy), Cochiar: G Splendiani (Rome U, Italy)

         Honorary President TMS Chang (McGill, Canada)

XII  1991 ISABI  (IV ISBS)  President: T.M.S.Chang(McGill, Canada) Cochair R.Geyer (Harvard, USA)

       XIII 1993 ISABI (V ISBS) President: R.Winslow(Letterman, USA) Cochairs: TMS Chang (McGill, Canada)          R.Riess (France), 1993

XII  1994 ISABI Congress   President: R. Langer (MIT, U.S.A.), Honorary president: TMS Chag (McGill)

       XIII 1996 ISABI (VI ISBS)  President: TMS Chang (McGill, Canada) Cochairs: A.G.Greenberg (Brown U, U.S.A) & E.Tsuchica (Waseda U, Japan)

       XIV 1997 ISABI Congress President: Denian Ba (President,Academy of Med Sci, China) & C.M. Yang (CAMS, China), Honorary President TMS Chang (McGill, Canada) 

XV 1997 ISABI (VII ISBS)  PresidentE.Tsuchida (Waseda U, Japan) Cochairs: S.Sekiguchi (Red Cross,

       Japan) & TMS Chang (McGill, Canada)

      XVI 1999 ISABI (VIII ISBS)  PresidentR.Winslow (UC at San Diego, U.S.A.)  Cochairs: TMS Chang     (McGill, Canada), M.Intaglietta(UC at San Diego, U.S.A.) & E.Tsuchida (Waseda U, Japan)

XV 2001 ISABI Congress President: E. Piskin (Ankara U, Turkey)  Honorary President: TMSChang (McGill)

       XVI 2003 ISABI (IX ISBS) President: K. Kobayashi (Keio U, Japan), Cochair: E.Tsuchida (Waseda U, Japan),  Honorary President: TMS Chang (McGill, Canada) 

XVII 2005 ISABI (X ISBS) President: G. Greenberg (Brown U, U.S.A.)  HonoraryPresident: TMS Chang

       XVIII  2007 ISABI (XI ISBS) President: Q. Liu (Vice-president, Chineswe Academyof Medical Sci., China) Executive President: R Xiu (Academy of Medical Sci, China), Honorary President: TMS Chang (McGill) 

       XIX  2009 ISABI (XII ISBS)  President: A. Mozzarelli (University of Parma, Italy), Vice Presidents Professor Enrico Bucci (University of Maryland) and Professor Clara Fronticelli ( Johns Hopkins University, U.S.A.)

       Honorary President: Professor TMS Chang (McGill University, Canada)

XX  2011 ISABI (XIII ISBS) President: Professor W Zapol (Harvard Medical School, U.S.A.)

       Honorary President: Professor TMS Chang (McGill University, Canada)

     XXI 2013 ISABI (XIV ISBS) President: Professor Zheng (BTI China), Vice presidents Professor Liu (BTI China) &  Professor Yang (BIT China), Honorary President, Professor Chang (McGill, Canada)

XXII 2015  ISABI (XV ISBS) President: Professor L Bulow (Lund, Sweden), Honorary President, Prof TMS Chang

XXIII 2017 ISABI Congress (XVI ISBS, V ISNS) Professor TMS Chang, 60th anniversary Conference on Artificial Cells in conjunction with XVI ISBS and V ISNS (McGill, Canada)

XXIV 2019 (XVII ISBS) China/Japan. Co-Presidents: Professor CM Yang (BTI CAMS, China) Professor Sakai (Mara, Japan); Honorary President: Professor TMS Chang (McGill, Canada)

XXV 2022 (XVIII ISBS) Cancelled because of pandemic

XXV 2004 (XIX ISBS) Co-presidents J Jahr & A Doctor (Maryland, USA). Honorary President: Professor TMS Chang (McGill, Canada)




ARTIFICIAL CELLS, NANOMEDICINE AND   BIOTECHNOLOGY, an international journal ( ) Publisher: Frances & Taylor, U.K.: 

This is a peer review journal that is the oldest journal in the field having started in

1972 "Biomaterial, Medical Devices & Artificial Organs, an international journal".

1979: Chang became the editor in chief and allows the name of the journal to change with time to reflect the frontier of research in the area. Before 2003 this journal was "Artificial Cells, Blood Substitutes and Immobilization Biotechnology").

2003: Starting in 2003 it was "Artificial Cells Blood Substitutes and Biotechnology. 

2012 it became Artificial Cells, Nanomedicine and Biotechnology.  Its demand is such that in 2016 the publisher has increased the issues from 6/year to 8/year with corresponding increase in the total pages that increased to 2,400 submission/year IN 2020.  This has become more than a full-time job. Furthermore, the publisher has changed this journal to an Open Access format that no longer allow publications from researchers of a number of countries. After 40 years as editor in chief this journal is now well established, he therefore resigned but was invited to stay on as Emeritus editor

Editor in chief:  1985-2020 TMS Chang (McGill, Canada) (emeritus editor 2020- );   Coeditors in chief: 2021- D Misra (USA) W Chrzanowski (Australia) P Roach (U.K.)

Please see home page: for more details



Editor in chief: TMS Chang (McGill,Canada)

In 2023, World Science Publisher (Official publisher of all the Nobel Prize Lectures since the beginning) started this new journal with hybrid Open Access so authors can decide whether they want to pay a fee for their papers to be open access. They invited me to be editor in chief of this new journal (I accepted this because it is important not to restrict those who do not want to pay the high open access fee). I am already the editor in chief for their book series on REGENERATIVE MEDICINE, ARTIFICIAL CELLS AND NANOMEDICINE since 2006




(World Science Publisher/Imperial College Press)

Editor in chief: TMS Chang (McGill,Canada)

            Volume 1:  Monograph by TMS Chang “ARTIFICIAL CELLS: Biotechnology, Nanomedicine, Regenerative Medicine, Blood Substitutes, Bioencapsulation and Cell-Stem Cell Therapy” Chang 2007 454 pages with full text. Now available free on  

            Volume 2: Present and future Therapies for End-Stage Renal Failure. Editors: Eli Friedman & MC Mallappallil (2010)

            Volume 3: Selected Topics in Nanomedicine. Editor: TMS Chang (2013)

            Volume 4: Hemoperfusion and plasma-perfusion: general, selective, immune and leucocyte adsorbents.

              Editors: TMS Chang, Y Endo, VG Nikolaev, T Tani, YT Yu and WH Zheng (2017)

              Chapter 1 available on  

            Volume 5: Nanobiotherapeutic blood substitute and oxygen-based therapeutics

               Editor in chief: TMS Chang, Coeditors: L Bulow, J Jahr, H Sakai & CM Yang) (2021). available free on  

           Volume 6:  Monograph By TMS Chang (2nd edition): “ARTIFICIAL CELLS: Biotechnology, Nanomedicine, Regenerative Medicine, Blood Substitutes, Immunotheraputics, Bioencapsulation and Cell-Stem Cell Therapy” (in preparation)





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