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Contact
information:
Telephone: (514) 987-5561
e-mail: andre.veillette@ircm.qc.ca
website:
http://www.ircm.qc.ca/en/recherche/statique/unite10.html
Projects for Thesis
Supervision:
1. Evaluation of the role of the adaptor
molecule EAT-2 in macrophages and dendritic cells, using an
EAT-2-deficient mouse generated in our laboratory.
2. Examination of the mechanism by which SAP, a
small adaptor molecule mutated in X-linked lymphoproliferative disease
in humans, regulates immune responses.
3. Characterization of the role and mechanism
of action of SLAM family receptors in immune cells.
Recent
Publications:
Veillette, A.,
Zhang, S., Shi, X., Dong, Z., Davidson, D. and Zhong, M.-C.
SAP expression in T cells, not in B cells, is required for humoral
immunity. Proc. Natl. Acad. Sci. In Press, 2008.
Veillette, A.,
Dong, Z. and Latour, S. (2007)
Consequence of the SLAM-SAP signaling pathway in innate-like and
conventional lymphocytes. Immunity 27: 698-710.
Davidson, D., Schraven, B. and
Veillette, A. (2007)
PAG-associated FynT regulates calcium signaling and promotes anergy in T
lymphocytes. Mol. Cell. Biol. 27: 1960-1973.
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