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Contact
information:
Telephone: (514) 934-1934, ext.
35046
e-mail address:
bernard.turcotte@mcgill.ca
website:http://www.medicine.mcgill.ca/endomuhc/Turcotte/turcotte.html
Projects for Thesis
Supervision:
1. Study of transcriptional regulators in yeast.
2. Drug resistance in the human pathogen
Candida albicans.
3. Mechanism of action of the anti-cancer drug
tirapazamine.
Recent
Publications:
Akache, B., S. MacPherson, M.-A.
Sylvain and B. Turcotte (2004)
Complex interplay among regulators of drug resistance in S. cerevisiae
J. Biol. Chem. 279: 27855-27860.
MacPherson, S., B. Akache, S.
Weber, X. De Deken, M. Raymond and B. Turcotte
(2005).
The Candida albicans zinc cluster protein Upc2p confers resistance to
antifungal drugs and is an activator of ergosterol biosynthetic genes
Antimicrob. Agents Chemother. 49: 1745-52.
Hellauer, K., G. Lesage, A.-M.
Sdicu and B. Turcotte (2005).
Large-scale analysis of genes that alter sensitivity to the anti-cancer
drug tirapazamine in Saccharomyces cerevisiae. Mol. Pharm. 68:
1365-1375.
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