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Contact
information:
Telephone: (514) 987-5712
e-mail address:
marie.trudel@ircm.qc.ca
website: http://www.ircm.qc.ca/en/recherche/statique/unite7.html
Projects for Thesis
Supervision:
1. Characterization of signaling by
polycystin-1 in renal development using transgenic and knock-out mice.
2. Analysis of homeobox transcription factor in
hematopoiesis/erythropoiesis.
3. Regulation of spatial chromatin conformation
in the transcriptional activation of globin gene.
Recent
Publications:
Rust, M.B., Alper, S.L., Rudhard,
Y., Shmukler, B.E., Vicente, R., Brugnara, C.,
Trudel, M., Jentsch, T.J. and Hübner, C.A. (2007)
Disruption of erythroid K-Cl co-transporters alters erythrocyte volume
and partially rescues erythrocyte dehydration in SAD mice. J. Clin.
Invest. 117: 1708-1717.
Felfly, H. and
Trudel, M. (2007)
Long term correction of b-thalassemia with
minimal cellular requirement and transplantation modalities. Mol. Ther.
15: 1701-1709.
Thivierge, C., Kurbegovic, A., Couillard, M., Guillaume,
R., Cote, O. and Trudel, M. (2006)
Overexpression of PKD1 causes polycystic kidney disease. Mol Cell
Biol, 26: 1538-1548.
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