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CHRISTIAN ROCHELEAU


Assistant Professor – Department of Medicine, Division of Experimental Medicine

Contact information:

Telephone: (514) 398-3979
e-mail: christian.rocheleau@mcgill.ca


Projects for Thesis Supervision:

1. Understanding the role of the trafficking protein KIC-1 in both vesicular trafficking and in promoting Ras signaling.

2. Characterization of the role of scaffold protein CNK-1 in Raf kinase activation.

3. Analysis of chromatin remodeling proteins and small RNA regulators in gene expression and in promoting the Ras pathway.


Recent Publications:

Rocheleau, C.E., Cullison, K., Huang, K., Bernstein, Y., Spilker, A.C. and Sundaram, M.V.
The Caenorhabditis elegans ekl (Enhancer of ksr-1 lethality) genes include putative components of a germline small RNA pathway. Genetics. In Press, 2008.

Rocheleau, C.E., Ronnlund, A., Tuck, S., and Sundaram, M.V. (2005).
Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling Proc. Natl. Acad. Sci. USA, 120, 11757-11762.

Rocheleau, C.E.*, Howard, R.M.*, Goldman, A.P., Volk, M.L., Girard, L.J., and Sundaram, M.V. (2002).
A lin-45 raf enhancer screen identifies eor-1, eor-2, and unusual alleles of Ras pathway genes in Caenorhabditis elegans. Genetics, 161, 121-131.