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Contact
information:
Telephone: (514) 412-4400, ext.
22342
e-mail address: janusz.rak@mcgill.ca
website:
http://www.hopitalpourenfants.com/en/research/mch.aspx
Projects for Thesis
Supervision:
1. Age-specific regulation of tumour angiogenesis.
2. The role of tumour microvesicles in angiogenesis
and metastasis.
3. Anticancer effects of coagulation system
inhibitors. The role of coagulation system in formation of the cancer
stem cell niche.
Recent
Publications:
Al-Nedawi, K., Meehan, B., Allison, A.C. and
Rak, J. (2009)
Endothelial expression of autocrine VEGF upon the uptake of
tumor-derived microvesicles containing oncogenic EGFR. Proc. Natl. Acad.
Sci. 106: 3794-3799.
Milsom, C., Yu, J., Mackman, N., Micaleff, J.,
anderson, M., guha, A. and Rak, J.
(2008)
Epidermal growth factor receptor-dependent upregulation of tissue factor
is modified by epithelial to mesenchymal transitions -
Implications for tumor angiogenesis. Cancer Res. 68: 1168-1176.
Al-Nedawi, K., Meehan, B., Micallef, J., Lhotak, V., May, L., Guha,
A. and Rak J.
(2008)
Intercellular transfer of the oncogenic EGFRvIII via tumor cell derived
microvesicles. Nature Cell Biology 5: 619-624.
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