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BASIL PETROF


Professor – Department of Medicine, Division of Experimental Medicine

Contact information:

Telephone: (514) 934-1934, ext. 35946
e-mail address: basil.petrof@mcgill.ca
website: http://www.meakins.mcgill.ca/meakins/petrof/index.htm


Projects for Thesis Supervision:

1. Determining the role of chemokines and chemokine receptors in muscle regeneration and muscular dystrophy pathogenesis in the diaphragm using transgenic mice and tissue culture models.

2. Determining the role of the cystic fibrosis transmembrane conductance regulator (CFTR) in diaphragmatic and peripheral skeletal muscle function.

3. Determining the role of Toll-like receptors in diaphragmatic and peripheral skeletal muscle dysfunction in sepsis and muscular dystrophy.


Recent Publications:

Yahiaoui, L., Gvozdic, D., Danialou, G., Mack, M. and Petrof, B.J. (2008)
CC family chemokines directly regulate myoblast responses to skeletal muscle injury. J. Physiol. 586: 3991-4004.

Khairallah, M., Khairallah, R.J., Young, M.E., Allen, B.G., Gillis, M.A., Danialou, G., Deschepper, C.F., Petrof, B.J., and Des Rosiers, C. (2008)
Sildenafil and cardiomyocyte-specific cGMP signaling prevent cardiomyopathic changes associated with dystrophin deficiency. Proc. Natl. Acad. Sci. 105: 7028-7033.

Divangahi, M., Demoule, A., Danialou, G., Yahiaoui, L., Bao, W., Xing, Z. and Petrof, B.J. (2007)
Impact of IL-10 on diaphragmatic cytokine expression and contractility during Psuedomonas infection. Am. J. Respir. Cell Mol. Biol. 36: 504-512.