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Contact
information:
Telephone: (514) 398-1521
e-mail address: arnim.pause@mcgill.ca
website:
http://www.mcgill.ca/biochemistry
http://www.med.mcgill.ca/cancer
Projects for Thesis
Supervision:
1. Functional characterization of the BHD
tumour suppressor.
2. Functional characterization of the VHL
tumour suppressor in ECM disposition.
3. Characterization of a novel tyrosine
phosphatase.
Recent
Publications:
Franovic A, Robert I, Smith K,
Kurban G, Pause A, Gunaratnam L, Lee
S.
Multiple acquired renal carcinoma tumor capabilities abolished upon
silencing of ADAM17. Cancer Res. 66: 8083-8090, 2006.
Kurban G, Hudon V, Duplan E, Ohm M,
Pause A.
Characterization of a von Hippel Lindau Pathway involved in
extracellular matrix remodeling, cell invasion, and angiogenesis. Cancer
Res. 66: 1313-1319, 2006.
Welbourn S, Green R, Gamache I, Dandache S,
Lohmann V, Bartenschlager R, Meerovitch K,
Pause A.
Hepatitis C virus NS2/3 processing is required for NS3 stability and
viral RNA replication. J. Biol. Chem. 280: 29604-29611, 2005.
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