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Vassilios Papadopoulos >






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Professor Department of Department of Medicine, Division of Experimental Medicine

Contact information:

Telephone: (514) 934-1934, ext. 44580
e-mail address: vassilios.papadopoulos@mcgill.ca

Projects for Thesis Supervision:

1. Understand the cellular and molecular mechanisms responsible for the initiation and maintenance of steroid biosynthesis in the gonads.

2. Examine the regulation of intracellular compartmentalization and homeostasis of the precursor cholesterol and steroid products by hormones and environmental factors.

3. Investigate the mechanisms underlying neurosteroid synthesis in brain, in health and disease.

4. Examine the role of intracellular compartmentalization and homeostasis of cholesterol in the progression of cancer.

Recent Publications:

Giatzakis C, Batarseh A, Dettin L, Papadopoulos V.
The role of Ets transcription factors in the basal transcription of the translocator protein (18kDa). Biochemistry  In Press, 2007.

Li W, Hardwick M, Rosenthal DR, Culty M, Papadopoulos V.
Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation. Biochemical Pharmacology 73: 491-503, 2007.

Liu J, Rone MB, Papadopoulos V.
Protein-protein interactions mediate cholesterol transport into mitochondria and steroid biosynthesis. J. Biol. Chem. 281: 38879-38893, 2006.