Professor – Department of Medicine, Division of Experimental Medicine

Contact information:

Telephone: (514) 340-8260, ext. 5293
e-mail address: kostas.pantopoulos@mcgill.ca
website: http://www.ladydavis.ca/en/kostaspantopoulos

Projects for Thesis Supervision:

1. Mechanism for IRP2 regulation.

2. Animal models of iron metabolism.

3. Regulation of hepcidin and hemojuvelin.

Recent Publications:

Schumann, K., Berbach, N., Kerling, C., Seifert, M., Fillebeen, C., Prysch, I., Reich, J., Weiss, G. and Pantopoulos, K.  (2010)
Iron absorption and distribution in TNF^ΔARE/+ mice, a model of chronic inflammation. J. Trace Elem. Med. Biol. 24: 58-66.

Zimmer, M., Ebert, B.L., Neil, C., Brenner, K., Papaioannou, I., Melas, A., Tolliday, N., Lamb, J., Pantopoulos, K., Golub, T. and Iliopoulos, O. (2008)
Small molecule inhibitors of HIF-2a translation link its 5'-UTR iron-responsive element (IRE) to oxygen sensing. Mol. Cell, 32: 838-848.

Wang, J., Chen, G., Lee, J. and Pantopoulos, K. (2008)
Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity. BMC Mol. Biol. 9:15.