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Contact
information:
Telephone: (514) 340-8248
e-mail address:
lpanasci@hotmail.com
website:
http://www.medicine.mcgill.ca/oncology/displayoncology.asp?Oncology_ID=23
Projects for Thesis
Supervision:
1. DNA repair( Rad51 homologous
recombinational repair and nonhomologous endjoining) vis-a-vis
anticancer drug resistance.
Recent
Publications:
Xu ZY, Loignon M, Han FY,
Panasci L, Aloyz R.
Xrcc3 induces cisplatin resistance by stimulation of Rad51-related
recombinational repair, S-phase checkpoint activation, and reduced
apoptosis. J Pharmacol Exp Ther. 2005 Aug;314(2):495-505.
Aloyz R, Grzywacz K, Xu ZY,
Loignon M, Alaoui-Jamali MA, Panasci L.
Imatinib sensitizes CLL lymphocytes to chlorambucil. Leukemia.
2004 Mar;18(3):409-14.
Panasci
L, Stinson S F, Melnychuk D, Sandor V, Miller Jr, Batist G,
Patenaude F, Bangash N, Panarello L, Alaoui-Jamali M and Sausville E.
SarCNU, a nitrosourea analogue on a day 1, 5 and 9 oral schedule: A
phase I and pharmacokinetic study in patients with advanced solid
tumors. J Clin Oncol 21:232-240, 2003.
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