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Contact
information:
Telephone: (514) 340-8222, ext.
5268
e-mail address:
miltiadis.paliouras@mcgill.ca
website:
http://www.medicine.mcgill.ca/oncology/fac/facandstaff_show.asp?Oncology_ID=304
Projects for Thesis
Supervision:
1. Developing a conditional
mlh1-loxp knock-out mouse to study hereditary non-polyposis colorectal
cancer (HNPCC) to use as a platform for novel therapeutics.
2. Utilizing genetic, molecular
biology, mass spectrometry, and systems biology approaches to identify
Androgen Receptor (AR) protein interactors to elucidate novel functional
pathways involved in prostate cancer development.
3. Correlating thyroglobulin
gene variants in patients with recurrent papillary thyroid cancer.
Recent
Publications:
Gottlieb B, Beitel LK, Nadaraja
A, Paliouras M, Trifiro M, Hunt M
(2012)
The androgen receptor gene mutations database: 2011 update. 2012 Feb.
14. doi: 0.1002/humu.22046 (Epub ahead of print).
Paliouras M,
Zaman N, Lumbroso R., Kapogeorgakis L, Beitel LK, Wang E, Trifiro M
(2011)
Dynamic rewriting of the androgen receptor protein interaction network
correlates with prostate cancer clinical outcomes. Integr. Biol. 3(10):
1020-1032.
Paliouras M,
Diamandis EP (2008)
The influence of intracellular signaling pthways on the
hormone-dependent human tissue kallikrein gene expression in breast
cancer cells. Tumour Biol. 29: 63-75.
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