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Contact
information:
Telephone: (514) 340-8222, ext.
5915
e-mail address:
stephanie.lehoux@mcgill.ca
website:
Projects for Thesis
Supervision:
1. Identify the signalling pathways associated
with vascular remodelling in vivo and ex vivo.
2. Understand the molecular mechanisms
underlying the athero-protective effects of shear stress.
3. Investigate atherosclerotic plaque formation
and regression in relation to endothelial function and inflammatory
response.
Recent
Publications:
Castier, Y., Ramkhelawn, B.,
Rious, S., Tedgui, A. and Lehoux, S.
(2009)
Role of NFkappaB in flow-induced vascular remodeling. Antioxid. Redox
Signal 11: 1641-1649.
Ramkhelawon, B., Vilar, J.,
Rivas, D., Mees, B., De Crom, R., Tedgui, A. and
Lehoux, S. (2009)
Shear stress regulates angiotensin type one receptor expression in
endothelial cells. Circ. Res. 105: 869-875.
Lemarie, C.A., Tharaux, P.I. and
Lehoux, S. (2010)
Extracellular matrix alterations in hpertensive vascular remodeling. J.
Mol. Cell. Cardiol. 48: 433-439.
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