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Contact
information:
Telephone: (514) 340-8260, ext.
5273
e-mail address:
michael.laughrea@staff.mcgill.ca
website:
Projects for Thesis
Supervision:
1. Role of RNA, viral and cellular proteins in
the dimerizaztion, encapsidation and reverse transcription of HIV-1
genomic RNA.
Recent
Publications:
Jalalirad, M. and
Laughrea, M. (2010)
Formation of immature and mature genomic RNA dimers in wild-type and
protease-inactive HIV-1: Differential roles of the Gag polyprotein,
nucleocapsid proteins NCp15, NCp9, NCp7, and the dimerization initiation
site. Virology 407: 225-236.
Kafaie, J., Song, R., Abrahamyan,
L., Mouland, A.J. and Laughrea, M.
(2008)
Mapping of nucleocapsid residues important for HIV-1 genomic RNA
dimerization and packaging. Virology, 375:592-610.
Song, R., Kafaie, J. and
Laughrea, M.
(2008)
Role of the 5'TAR stem-loop and the U5-AUG duplex in
dimerization of HIV-1 genomic RNA. biochemistry, 47: 3283-3293.
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