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Contact
information:
Telephone: (514) 843-1632
e-mail address:
geoffrey.hendy@mcgill.ca
website:
http://www.casrdb.mcgill.ca
http://www.hcru.mcgill.ca/HG.htm
Projects for Thesis
Supervision:
1. Molecular genetics of the calcium-sensing
receptor.
2. Multiple endocrine neoplasia type 1 gene
product (menin).
3. Granins and role in neuroendocrine secretion.
Recent
Publications:
Zajickova, K., Vrbikova, J.,
Canaff, L., Pawelek, P.D., Goltzman, D. and
Hendy,
G.N. (2007)
Identification and functional characterization of a novel mutation in
the calcium-sensing receptor gene in familial hypocalciuric
hypercalcemia: modulation of clinical severity by vitamin D status. J.
Clin. Endocrinol. 92: 2616-2623
Yun, F.H.J., Wong, B.-Y., Chase, M. Shuen, A.Y.,
Canaff, L., Thongthai, K., Siminovitch, K.,
Hendy, G.N. and Cole, D.E.C.
(2007)
Genetic variation at the calcium-sensing receptor (CASR) locus:
Implications for clinical molecular diagnostics. Clin. Biochem. 40:
551-561, 2007.
Pidasheva, S., Grant, M., Canaff, L., Ercan,
O., Kumar, U. and Hendy, G.N.
(2006)
The calcium-sensing receptor (CASR) dimerizes in the endoplasmic
reticulum: biochemical and biophysical characterization of novel CASR
mutations causing familial hypocalciuric hypercalcemia. Hum. Molec.
Genet. 15: 2200-2209.
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