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Contact
information:
Telephone: (514) 340-8222, ext.
4930
e-mail address: mark.basik@mcgill.ca
website:
http://www.mcgill.ca/translational-research-cancer/researcher-biographies/basik/
http://markbasiklab.mcgill.ca/people.html
Projects for Thesis
Supervision:
1. Genomics and breast and colon cancer:
Mapping genomic amplifications and deletions to identify novel oncogenes
and tumor suppressors, as targets for therapy and diagnostic markers.
2. Mechanisms of resistance to anti-growth
factor therapy (Herceptin and Erbitux).
3. Tumor-stromal cell interaction - identifying
molecular interactions between tumor cells and carcinoma-associated
fibroblasts.
Recent
Publications:
Hassan, S., Baccarelli, A., Salvucci, O. and
Basik, M. (2008)
Plasma stromal cell-derived factor (SDF-1): Host-derived marker
predictive of distant metastasis in breast cancer. Clin. Cancer Res., In
Press.
Hassan, S., Ferrario, C., Mamo, A. and
Basik, M. (2007)
Tissue microarrays: emerging standard for clinical biomarker validation.
Invited review for Curr. Opinion in Biotech., In Press.
Khambata-Ford, S., Garrett, C.R., Meropol,
N.J., Basik, M., Harbison,
C.T., Wu, S., Wong, T.W., Huang, X., Takimoto, C.H., Godwin, A.K., Tan,
B.R., Krishnamurthi, S.S., Burris, H.A., Poplin, E.A., Hidalgo, M.,
Baselga, J., Clark, E.A. and Maura, D.J. (2007)
Expression of epiregulin and amphiregulin and K-RAS mutation
status are associated with disease control in metastatic colorectal
cancer patients treated with cetuximab. J. Clin. Oncol. 25: 3230-3237.
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