|
Contact
information:
Telephone: (514) 987-5739
e-mail address:
jacques.archambault@ircm.qc.ca
website:
http://www.ircm.qc.ca/microsites/molecularvirology/en/
Projects for Thesis
Supervision:
1. Mechanism of transcriptional transactivation
by the papillomavirus E2 regulatory protein and characterization of
small molecule inhibitors thereof.
2. Molecular and functional characterization of
HPV variants with increased oncogenecity.
3. Identification of host factors interacting
with the papillomavirus E1 helicase and their roles in viral DNA
replication.
Recent
Publications:
D'Abramo, C.M. and
Archambault,
J. (2010)
Small molecule inhibitors of human papillomavirus protein-protein
interactions. Infectious Disorders - Drug Targets, In Press.
Fradet-Turcotte, A., Morin, G., Lehoux, M.,
Bullock, P.A. and Archambault, J.
(2010)
Development of quantitative and high-throughput assays of polyomavirus
and papillomavirus DNA replication. Virology (Epub ahead of print).
Fradet-Turcotte, A., Brault, K., Titolo, S., Howley,
P.M. and Archambault, J. (2009)
Characterization of papillomavirus E1 helicase mutants defective for
interaction with the SUMO-cogatingnju enzyme Ubc9. Virology 395(2):
190-201.
|
