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Contact
information:
Telephone: (514) 340-8222, ext.
5288
e-mail address: raquel.aloyz@mcgill.ca
or raloyz@yahoo.com
website: http://www.mcetc.ca
http://www.mcgill.ca/cancergenetics
Projects for Thesis
Supervision:
1. Mechanisms of Dasatinib toxicity and
sensitization of standard therapy in chronic lymphocytic leukemia.
2. MRI-based tumor targeting enhancement with
magnetotactic bacterial carriers.
3. Evaluation of DNA-PK inhibitors in malignant
human cells.
4. Toward the biological treatment of
BRCA1-related breast cancer: EGF, EGFR and tyrosine kinase inhibitors.
Recent
Publications:
Amrein, L., Hernandez, T.A.,
Ferrario, C., Johnston, J., Gibson, S.B., Panasci, L. and
Aloyz, R. (2008)
Dasatinib sensitizes primary chronic lymphocytic leukaemia lymphocytes
to chlorambucil and fludarabine in vitro. Br. J. Haematol. 143:
698-706.
Yasmeen, A., Liu, W., Dekhil, H., Kassab, A.,
Aloyz, R., Foulkes, W.D.
and Al Moustafa, A.E. (2008)
BRCA1 mutations contribute to cell motility and invasion by affecting
its main regulators. Cell Cycle 7:23.
Tischkowitz, M.D., Yilmaz, A., Chen, L.Q.,
Karyadi, D.M., Novak, D., Kirchhoff, T., Hamel, N., Tavtigian, S.V.,
Kolb, S., Bismar, T.A., Aloyz, R.,
Nelson, P.S., Hood, L., Narod, S.A., White, K.A., Ostrander, E.A.,
Isaacs, W.B., Offit, K., Cooney, K.A., Stanford, J.L., Foulkes, W.D.
(2008)
Identification and characterization of novel SNPs in CHEK2 in Ashkenazi
Jewish men with prostate cancer. Cancer Lett. 270: 173-180.
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